A selection of scholarship from faculty members of the Department of Biomedical Sciences (BMS) at Arthur A. Dugoni School of Dentistry, University of the Pacific.

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Submissions from 2025

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The impact of oral health disparities on smoking prevalence, Pedro H. Carneiro, Alice Zhang, William Zhao, David M. Ojcius, Ladan Daly, and Cássio Luiz C. Almeida-da-Silva

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Hirsutella sinensis polysaccharides and Parabacteroides goldsteinii reduce lupus severity in imiquimod-treated mice, Shih-Hsin Chang, Yun-Fei Ko, Jian-Ching Liau, Cheng-Yeu Wu, Tsong-Long Hwang, David M. Ojcius, John D. Young, and Jan Martel

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Advancing cancer diagnosis and treatment: Integrating molecular biomarkers and emerging technologies, Yu-Sun Chang and David M. Ojcius

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Bridging oral and systemic health: exploring pathogenesis, biomarkers, and diagnostic innovations in periodontal disease, Max Foroughi, Mahmoud Torabinejad, Nikola Angelov, David M. Ojcius, Keykavous Parang, Marcus Ravnan, and Jerika Lam

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Circadian rhythmicity and human health, Jan Martel, David M. Ojcius, and John D. Young

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Effects of light, electromagnetic fields and water on biological rhythms, Jan Martel, Nicolas Rouleau, Nirosha J. Murugan, Wei-Chun Chin, David M. Ojcius, and John D. Young

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Role of the P2X7 receptor in intestinal inflammation due to infection with the oral pathogen Porphyromonas gingivalis, Lorraine Oliveira-Cruz, Nayara Carvalho-Barbosa, Fabiana Cristina-Rodrigues, Thaís N. Côrtes, Kamila Guimarães-Pinto, André L. Amorim da Costa, Isadora S. de Lima, Talita G. B. Lourenço, Archimedes B. Castro-Junior, Alessandra D. Almeida Filardy, Ana Paula V. Colombo, Heitor S. P. de Souza, Christina M. Takiya, David M. Ojcius, Luiz Eduardo B. Savio, and Robson Coutinho-Silva

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Aerosol Dispersion and Efficacy of Protective Strategies During Dental Procedures, Mustafa Radif, Andrew Young, Eric Salmon, David M. Ojcius, and Shika Gupta

Submissions from 2024

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Traditional approaches and recent tools for studying inflammasome activity, Cássio Luiz C. Almeida-da-Silva, Aline C. de Abreu Moreira-Souza, and David M. Ojcius

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Mineralo-organic particles inhibit influenza A virus infection by targeting viral hemagglutinin activity, Huan-Jung Chiang, Hsin-Hsin Peng, Kuo-Feng Wang, Kuei-Ching Hsiung, Chieh-Yu Liang, Shun-Li Kuo, David M. Ojcius, John D. Young, and Shin-Ru Shih

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Multiple energy X-ray imaging of metal oxide particles inside gingival tissues, Jarrod Cortez, Ignacio Romero, Jason Ngo, Md S. T. Azam, Chuang Niu, Cássio Luiz C. Almeida-da-Silva, Leticia F. Cabido, David M. Ojcius, Wei-Chun Chin, Ge Wang, and Changqing Li

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miRNAs mediate the impact of smoking on dental pulp stem cells via the p53 pathway, Leyla T. Hardin, Nabil Abid, David Vang, Xiaoyuan Han, Der Thor, David M. Ojcius, and Nan Xiao

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Unveiling the mycobiota: The fungal frontier of human health, Parvati Iyer and David M. Ojcius

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Biological functions of extracellular vesicles from mammalian cells, Jean M. Kanellopoulos, Frédéric Rieux-Laucat, and David M. Ojcius

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Lifestyle interventions to delay senescence, Jan Martel, David M. Ojcius, and John D. Young

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Senescence: No country for old cells, Jan Martel, David M. Ojcius, and John D. Young

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Dentistry: Our Sustainable Future, Nader A. Nadershahi and David M. Ojcius

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Frankincense (Boswellia serrata) Extract Effects on Growth and Biofilm Formation of Porphyromonas gingivalis, and Its Intracellular Infection in Human Gingival Epithelial Cells, David Vang, Aline C. de Abreu Moreira-Souza, Nicholas Zusman, German Moncada, Harmony M. Dakafay, Homer Asadi, David M. Ojcius, and Cássio Luiz C. Almeida-da-Silva

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Magnesium-enriched deep-sea water inhibits NLRP3 inflammasome activation and dampens inflammation, Hsueh-Hsiao Wang, Chi-Ruei Huang, Hsin-Chung Lin, Hsin-An Lin, Yu-Jen Chen, Kuen-Jou Tsai, Chieh-Tien Shih, Kuo-Yang Huang, David M. Ojcius, Ming-Hang Tsai, Kuang-Wen Tseng, and Lih-Chyang Chen

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Caenorhabditis elegans as a Convenient Animal Model for Microbiome Studies, Cheng-Yeu Wu, Scott Davis, Neekita Saudagar, Shrey Shah, William Zhao, Arnold Stern, Jan Martel, David M. Ojcius, and Hung-Chi Yang

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Development of T cell antigen-based human coronavirus vaccines against nAb-escaping SARS-CoV-2 variants, Hao Zhou, Ping Leng, Yang Wang, Kaiwen Yamg, Chen Li, David M. Ojcius, Pengfei Wang, and Shibo Jiang

Submissions from 2023

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Interactions between silica and titanium nanoparticles and oral and gastrointestinal epithelia: consequences for inflammatory diseases and cancer., Cássio Luiz C. Almeida-da-Silva, Leticia F. Cabido, Wei-Chun Chin, Ge Wang, David M. Ojcius, and Changqing Li

A combination of self-study assignments and small-group discussions in Applied Anatomy teaching for dental students, Cassio Luiz Coutinho Almeida-Da-Silva, Homer Asadi, Xiaoyuan Han, Nan Tori Xiao, Der Thor, and Annie Han

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Interactions between silica and titanium nanoparticles and oral and gastrointestinal epithelia: Consequences for inflammatory diseases and cancer, Cassio Luiz Coutinho Almeida-Da-Silva, Leticia Ferreira Cabido, Wei Chun Chin, Ge Wang, David M. Ojcius, and Changqing Li

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The role of NOD-like receptors in innate immunity, Cassio Luiz Coutinho Almeida-Da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, and David M. Ojcius

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The role of NOD-like receptors in innate immunity, Cássio Luiz C. Almeida-da-Silva, Luiz Eduardo B. Savio, Robson Coutinho-Silva, and David M. Ojcius

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Inactivation of mitochondrial pyruvate carrier promotes NLRP3 inflammasome activation and gout development via metabolic reprogramming, Lih-Chyang Chen, Yu-Jen Chen, Hsin-An Lin, Wu-Chien Chien, Kuen-Jou Tsai, Chi-Hsiang Chung, Jui-Yang Wang, Chien-Chou Chen, Nan-Shih Liao, Chieh-Tien Shih, Yi-Ying Lin, Chi-Ning Huang, David M. Ojcius, Kuo-Yang Huang, and Hsin-Chung Lin

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Multiple energy X-ray imaging of metal oxide particles inside gingival tissues, Jarrod Cortez, Ignacio Romero, Jason Ngo, Md Sayed Tanveere Azam, Chuang Niu, Cassio Luiz Coutinho Almeida-Da-Silva, Leticia Ferreirad Cabido, David M. Ojcius, Wei-Chunb Chin, Gee Wang, and Changqinga Li

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Towards multiomic analysis of oral mucosal pathologies, Jakob Einhaus, Xiaoyuan Han, Dorien Feyaerts, John Sunwoo, Brice Gaudilliere, Somayeh H. Ahmad, Nima Aghaeepour, Karl Bruckman, David M. Ojcius, Christian M. Schürch, and Dyani K. Gaudilliere

Whiteboard animated videos facilitated learning in biomedical science: a retrospective study among first-year dental students, Xiaoyuan Han, Meixun Sinky Zheng, Der Thor, Nan Tori Xiao, Cassio Luiz Coutinho Almeida-Da-Silva, and Homer Asadi

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Cigarette smoking exposure disrupts the regenerative potential of dental pulp stem cells, Leyla T. Hardin, David Vang, Der Thor, Xiaoyuan Han, Fatima Mashkoor, Tamer Alpagot, David M. Ojcius, and Nan Xiao

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Influence of electromagnetic fields on the circadian rhythm: Implications for human health and disease, Jan Martel, Shih-Hsin Chang, Gaétan Chevalier, David M. Ojcius, and John D. Young

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Is a return to nature a piece of the health puzzle?, Jan Martel and David M. Ojcius

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Association between Periodontal Disease and Cognitive Impairment in Adults, Najwane Said-Sadier, Batoul Sayegh, Raymond Farah, Linda A. Abbas, Rania Dweik, Norina Tang, and David M. Ojcius

Clinical Case-Based Discussions in Applied Physiology for Dental Students, Nan Tori Xiao, Der Thor, Meixun Sinky Zheng, Xiaoyuan Han, Cassio Luiz Coutinho Almeida-Da-Silva, and Homer Asadi

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A flash of inspiration: Enhancing dental student drug recognition, Benjamin D. Zeitlin

Submissions from 2022

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Effects of Frankincense Compounds, Cassio Luiz Coutinho Almeida-Da-Silva, Nallusamy Sivakumar, Homer Asadi, Anna Chang-Chien, M. Walid Qoronfleh, David M. Ojcius, and Musthafa Mohamed Essa

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Effects of Frankincense Compounds on Infection, Inflammation, and Oral Health, Cassio Luiz Coutinho Almeida-Da-Silva, Nallusamy Sivakumar, Homer Asadi, Anna Chang-Chien, M. Walid Qoronfleh, David M. Ojcius, and Musthafa Mohamed Essa

Submissions from 2021

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Effects of electronic cigarette aerosol exposure on oral and systemic health, Cassio L. C. Almeida-da-Silva, Harmony M. Dakafay, Kenji O'Brien, Dallin Montierth, Nan Xiao, and David M. Ojcius

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Cigarette smoke stimulates SARS-CoV-2 internalization by activating AhR and increasing ACE2 expression in human gingival epithelial cells, Cassio Luiz Coutinho Almeida-Da-Silva, Harmony Matshik Dakafay, Kaitlyn Liu, and David M. Ojcius

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Cigarette smoke stimulates sars-cov-2 internalization by activating ahr and increasing ace2 expression in human gingival epithelial cells, Cassio Luiz Coutinho Almeida-Da-Silva, Harmony Matshik Dakafay, Kaitlyn Liu, and David M. Ojcius

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Making it easier to be a patient in times of a pandemic, David Chambers, Michelle Brady, David M. Ojcius, and Evelyn Cuny

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Guest view: Wildfire smoke brings health hazard; here’s how to protect yourself, Adriana Chan, Melissa Nguyen, Adam Acevedo, and David M. Ojcius

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Differential involvement of the canonical and noncanonical inflammasomes in the immune response against infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum, Kívia Queiroz De Andrade, Cassio Luiz Coutinho Almeida-Da-Silva, David M. Ojcius, and Robson Coutinho-Silva

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Bacteriophage therapy of bacterial infections: The rediscovered frontier, Nejat Düzgüneş, Melike Sessevmez, and Metin Yildirim

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Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19, Dorien Feyaerts, Julien Hedou, Joshua Gillard, Han Chen, Eileen S. Tsai, Laura S. Peterson, Kazuo Ando, Monali Manohar, Evan Do, Gopal K.R. Chinthrajah, Christopher M. Warren, Rich Wittman, Justin G. Meyeroqitz, Edward A. Ganio, Ina A. Stelzer, Xiaoyuan Han, Franck Verdonk, Dyani K. Gaudilliere, Nilanjan Mukherjee, Amy S. Tsai, Kristen K. Rumer, Sizun Jiang, Sergio Ivan Valdes Ferrer, J. Daniel Kelly, David Furman, Nima Aghaeepour, Martin S. Angst, Scott D. Boyd, Benjamin A. Pinsky, Garry P. Nolan, Kari C. Nadeau, Brice Gaudilliere, and David R. McIlwain

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Proteomic signatures predict preeclampsia in individual cohorts but not across cohorts – implications for clinical biomarker studies, Mohammad Sajjad Ghaemi, Adi L. Tarca, Roberto Romero, Natalie Stanley, Ramin Fallahzadeh, Athena Tanada, Anthony Culos, Kazuo Ando, Xiaoyuan Han, Yair J. Blumenfield, Maurice L. Druzin, Yasser Y. El-Sayed, Ronald S. Gibbs, Virginia D. Winn, Kevin Contrepois, Xuefeng B. Ling, Ronald J. Wong, Gary M. Shaw, David K. Stevenson, Brice Gaudilliere, Nima Aghaeepour, and Martin S. Angst

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Structural and Functional Features of the P2X4 Receptor: An Immunological Perspective, Jean M. Kanellopoulos, Cássio Luiz Coutinho Almeida-da-Silva, Sirje Rüütel Boudinot, and David M. Ojcius

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Neither B cell nor T cell – The unique group of innate lymphoid cells, Jean M. Kanellopoulos and David M. Ojcius

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Guest view: Caution needed to return to normal after COVID-19, Steven Leung, Michelle Sabin, Evelyn Cuny, and David M. Ojcius

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Does COVID-19 contribute to development of neurological disease?, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Abid Bhat, Shasthara Paneyala, Duraisamy Patteswari, Meena Kishore Sakharkar, Hamdan Hamdan, David M. Ojcius, Srinivasa Rao Bolla, Musthafa Mohamed Essa, Saravana Babu Chidambaram, and M. Walid Qoronfleh

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Multiomics Longitudinal Modeling of Preeclamptic Pregnancies, Ivana Maric, Kevin Contrepois, Mira Moufarrej, Ina A. Stelzer, Dorien Feyaerts, Xiaoyuan Han, Andy Tang, Natalie Stanley, Ronald J. Wong, Gavin M. Traber, Mathew Ellenberger, Alan Chang, Ramin Fallahzadeh, Huda Nassar, Martin Becker, Maria Xenochristou, Camilo Espinosa, Davide De Francesco, Mohammad Sajjad Ghaemi, Elizabeth Costello, Anthony Culos, Xuefend B. Ling, Karl G. Sylvester, Gary L. Darmstadt, Virginia D. Winn, Gary M. Shaw, David A. Relman, Stephen R. Quake, Martin S. Angst, Michael P. Snyder, David K. Stevenson, Brice Gaudilliere, and Nima Aghaeepour

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Recent advances in the field of caloric restriction mimetics and anti-aging molecules, Jan Martel, Shih Hsin Chang, Cheng Yeu Wu, Hsin Hsin Peng, Tsong Long Hwang, Yun Fei Ko, John D. Young, and David M. Ojcius

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The tight-loose-tight approach applied to remote teaching in biomedical sciences, Ana C. Morandini and Homer Asadi

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Embracing video production as a powerful tool in dental education, Ana C. Morandini, Erivan S. Ramos-Junior, Meixun S. Zheng, and Rishi Desai

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Immunotherapies for Neurodegenerative Diseases, Ibrahim Mortada, Raymond Farah, Sanaa Nabha, David M. Ojcius, Youssef Fares, Wassim Y. Almawi, and Najwane S. Sadier

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Comparison of the effect of cigarette smoke on mesenchymal stem cells and dental stem cells, Brandon Nguyen, Tamer Alpagot, Heesoo Oh, David M. Ojcius, and Nan Xiao

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Ganoderma Lucidum Stimulates Autophagy-Dependent Longevity Pathways in Caenorhabditis Elegans and Human Cells, Hsin Hsin Peng, Cheng Yeu Wu, Yuan Chao Hsiao, Jan Martel, Po Yuan Ke, Chen Yaw Chiu, Jian Ching Liau, I. Te Chang, Yu Hsiu Su, Yun Fei Ko, John D. Young, and David M. Ojcius

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Single-cell Analysis of the Neonatal Immune System Across the Gestational Age Continuum, Laura S. Peterson, Julien Hedou, Edward Ganio, Ina A. Stelzer, Dorien Feyaerts, Eliza Harbert, Yamini Adusumelli, Kazuo Ando, Eileen S. Tsai, Amy S. Tsai, Xiaoyuan Han, Megan Ringle, Pearl Houghteling, Jonathan Reiss, David Lewis, Virginia D. Winn, Martin S. Angst, Nima Aghaeepour, David K. Stevenson, and Brice Gaudilliere

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Neanderthal cranial remains from Baume Moula-Guercy (Soyons, Ardèche, France), Gary D. Richards, Gaspard Guipert, Rebecca S. Jabbour, and Alban R. Defleur

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Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset, Ina A. Stelzer, Mohammad Sajjad Ghaemi, Xiaoyuan Han, Kazuo Ando, Julien J. Hédou, Dorien Feyaerts, Laura S. Peterson, Kristen K. Rumer, Eileen S. Tsai, Edward A. Ganio, Dyani K. Gaudillière, Amy S. Tsai, Benjamin Choisy, Lee P. Gaigne, Franck Verdonk, Danielle Jacobsen, Sonia Gavasso, Gavin M. Traber, Mathew Ellenberger, Natalie Stanley, Martin Becker, Anthony Culos, Ramin Fallahzadeh, Ronald J. Wong, Gary L. Darmstadt, Maurice L. Druzin, Virginia D. Winn, Ronald S. Gibbs, and Xuefeng B. Ling

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Is neurotrophic factor a second language that neuron and tooth speak?, Nan Xiao

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Neurotrophins BDNF and NT4/5 accelerate dental pulp stem cell migration, Nan Xiao, Der Thor, and Wei Y. Yu

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Student preferences impact outcome of flipped classroom in dental education: Students favoring flipped classroom benefited more, Nan Xiao, Der Thor, and Meixun S. Zheng

Submissions from 2020

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Immune response against Chlamydia trachomatis via toll-like receptors is negatively regulated by SIGIRR, Mufadhal Al-Kuhlani, Graham Lambert, Sukumar Pal, Luis de la Maza, and David M. Ojcius

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SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends, Awatef Allouch, Cristina Di Primio, Audrey Paoletti, Gabrielle Lê-Bury, Frédéric Subra, Valentina Quercioli, Roberta Nardacci, Annie David, Héla Saïdi, Anna Cereseto, David M. Ojcius, Guillaume Montagnac, Florence Niedergang, Gianfranco Pancino, Asier Saez-Cirion, Mauro Piacentini, Marie Lise Gougeon, Guido Kroemer, and Jean Luc Perfettini

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Effects of electronic cigarette aerosol exposure on oral and systemic health, Cássio Luiz Coutinho Almeida-da-Silva, Harmony Matshik Dakafay, Kenji O'Brien, Dallin Montierth, Nan Xiao, and David M. Ojcius

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Sleep Deprivation and Neurological Disorders, Muhammed Bishir, Abid Bhat, Musthafa Mohamed Essa, Okobi Ekpo, Amadi O. Ihunwo, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Sulie Chang, Saravana Babu Chidambaram, Meena Kishore Sakharkar, Gilles J. Guillemin, M. Walid Qoronfleh, and David M. Ojcius

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Is there an association between oral health and severity of COVID-19 complications?, Nathalie Botros, Parvati Iyer, and David M. Ojcius

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The role of Glial cell derived neurotrophic factor in head and neck cancer, Hongbin Cao, Qian He, Rie von Eyben, Joshua Bloomstein, Dhanya K. Nambiar, Vignesh Viswanathan, Sonya Aggarwal, Shirley Kwok, Rachel Liang, Amanda J. Koong, James S. Lewis Jr., Christina Kong, Nan Xiao, and Quynh-Thu Le

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Photocytotoxicity of liposomal zinc phthalocyanine in oral squamous cell carcinoma and pharyngeal carcinoma cells, Jennifer Cheung, Diana Furukawa, Raymond Pandez, Metin Ylldlrlm, Adria Frazier, Jaroslaw Piskorz, Nejat Düzgüneş, and Krystyna Konopka

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Mitochondrial oxidative phosphorylation complex regulates NLRP3 inflammasome activation and predicts patient survival in nasopharyngeal carcinoma, I. Che Chung, Lih Chyang Chen, Ngan Ming Tsang, Wen Yu Chuang, Tzu Chieh Liao, Sheng Ning Yuan, Chun Nan OuYang, David M. Ojcius, Chih Ching Wu, and Yu Sun Chang

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EFLA 945 restricts AIM2 inflammasome activation by preventing DNA entry for psoriasis treatment, I. Che Chung, Sheng Ning Yuan, Chun Nan OuYang, Sheng I. Hu, Hsin Chung Lin, Kuo Yang Huang, Wei Ning Lin, Yu Ting Chuang, Yu Jen Chen, David M. Ojcius, Yu Sun Chang, and Lih Chyang Chen

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Integration of mechanistic immunological knowledge into a machine learning pipeline improves predictions, Anthony Culos, Amy S. Tsai, Natalie Stanley, Martin Becker, Mohammad S. Ghaemi, David R. McIlwain, Ramin Fallahzadeh, Athena Tanada, Huda Nassar, Camilo Espinosa, Maria Xenochristou, Edward Ganio, Laura Peterson, Xiaoyuan Han, Ina A. Stelzer, Kazuo Ando, Dyani Gaudilliere, Thanaphong Phongpreecha, Ivana Marić, Alan L. Chang, Gary M. Shaw, David K. Stevenson, Sean Bendall, Kara L. Davis, Wendy Fantl, Garry P. Nolan, Trevor Hastie, Robert Tibshirani, and Martin S. Angst

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Possible role of tryptophan and melatonin in COVID-19, Musthafa Mohamed Essa, Hamdan Hamdan, Saravana Babu Chidambaram, Buthainah Al-Balushi, Gilles J. Guillemin, David M. Ojcius, and M. Walid Qoronfleh

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M16-Type metallopeptidases are involved in virulence for invasiveness and diffusion of leptospira interrogans and transmission of leptospirosis, Yu Mei Ge, Ai Hua Sun, David M. Ojcius, Shi Jun Li, Wei Lin Hu, Xuai Lin, and Jie Yan

Longitudinal Profile of Third-Trimester Pregnancies Identifies a Molecular Switch That Predicts the Onset of Labor, Xiaoyuan Han

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Impact of COVID-19 on dental education in the United States, Parvati Iyer, Kalid Aziz, and David M. Ojcius

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Enhancement of cell proliferation and motility of mammalian cells grown in co-culture with Pichia pastoris expressing recombinant human FGF-2, Henry Hieu M. Le, David Vang, Nadia Amer, Tou Vue, Colwin Yee, Hyam Kaou, Joseph S. Harrison, Nan Xiao, Joan Lin-Cereghino, Geoff P. Lin-Cereghino, and Der Thor

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Enhancement of cell proliferation and motility of mammalian cells grown in co-culture with Pichia pastoris expressing recombinant human FGF-2, Henry Hieu M. Le, David Vang, Nadia Amer, Tou Vue, Colwin Yee, Hyam Kaou, Joseph S. Harrison, Nan Tori Xiao, Joan Lin-Cereghino, Geoff P. Lin-Cereghino, and Der Thor

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Cbl negatively regulates nlrp3 inflammasome activation through glut1-dependent glycolysis inhibition, Hsin Chung Lin, Yu Jen Chen, Yau Huei Wei, Yu Ting Chuang, Su Heng Hsieh, Jing Yu Hsieh, Yi Lin Hsieh, David M. Ojcius, Kuo Yang Huang, I. Che Chung, Sheng Ning Yuan, Yu Sun Chang, and Lih Chyang Chen

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Does COVID-19 contribute to development of neurological disease?, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Abid Bhat, Shasthara Paneyala, Duraisamy Patteswari, Meena K. Sakharkar, Hamdan Hamdan, David M. Ojcius, Srinivasa R. Bolla, Musthafa M. Essa, Saravana B. Chidambaram, and M. Walid Qoronfleh

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Could nasal nitric oxide help to mitigate the severity of COVID-19?, Jan Martel, Yun Fei Ko, John D. Young, and David M. Ojcius

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Phytochemicals as Prebiotics and Biological Stress Inducers, Jan Martel, David M. Ojcius, Yun Fei Ko, and John D. Young

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Emerging use of senolytics and senomorphics against aging and chronic diseases, Jan Martel, David M. Ojcius, Cheng Yeu Wu, Hsin Hsin Peng, Laurent Voisin, Jean Luc Perfettini, Yun Fei Ko, and John D. Young

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Plant and fungal products that extend lifespan in caenorhabditis elegans, Jan Martel, Cheng Yeu Wu, Hsin Hsin Peng, Yun Fei Ko, Hung Chi Yang, John D. Young, and David M. Ojcius

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S-seco-porphyrazine as a new member of the seco-porphyrazine family – Synthesis, characterization and photocytotoxicity against cancer cells, Dariusz T. Mlynarczyk, Jaroslaw Piskorz, Lukasz Popenda, Magdalena Stolarska, Wojciech Szczolko, Krystyna Konopka, Stefan Jurga, Lukasz Sobotta, Jadwiga Mielcarek, Nejat Düzgüneş, and Tomasz Goslinski

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Embracing video production as a powerful tool in dental education, Ana C. Morandini, Erivan S. Ramos-Junior, Meixun Sinky Zheng, and Rishi Desai

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The role of medicine and technology in shaping the future of oral health, N. Nayyar, David M. Ojcius, and A. A. Dugoni

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Lessons learned from the 2019-nCoV epidemic on prevention of future infectious diseases, Xingchen Pan, David M. Ojcius, Tianyue Gao, Zhongsheng Li, Chunhua Pan, and Chungen Pan

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Multiomic immune clockworks of pregnancy, Laura S. Peterson, Ina A. Stelzer, Amy S. Tsai, Mohammad S. Ghaemi, Xiaoyuan Han, Kazuo Ando, Virginia D. Winn, Nadine R. Martinez, Kevin Contrepois, Mira N. Moufarrej, Stephen Quake, David A. Relman, Michael P. Snyder, Gary M. Shaw, David K. Stevenson, Ronald J. Wong, Petra Arck, Martin S. Angst, Nima Aghaeepour, and Brice Gaudilliere

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CD73-dependent adenosine dampens interleukin-1β-induced CXCL8 production in gingival fibroblasts: Association with heme oxygenase-1 and adenosine monophosphate-activated protein kinase, Erivan Schnaider Ramos-Junior, Michael Pedram, Renee E. Lee, Drake Exstrom, Özlem Yilmaz, Robson Coutinho-Silva, David M. Ojcius, and Ana Carolina Morandini

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Cytolethal distending toxin-induced release of interleukin-1β by human macrophages is dependent upon activation of glycogen synthase kinase 3β, spleen tyrosine kinase (Syk) and the noncanonical inflammasome, Bruce J. Shenker, Lisa M. Walker, Zeyed Zekavat, David M. Ojcius, Pei Rong Huang, and Kathleen Boesze-Battaglia

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VoPo leverages cellular heterogeneity for predictive modeling of single-cell data, Natalie Stanley, Ina A. Stelzer, Amy S. Tsai, Ramin Fallahzadeh, Edward A. Ganio, Martin Becker, Thanaphong Phongpreecha, Huda Nassar, Sajjad Ghaemi, Ivana Maric, Anthony Culos, Alan L. Chang, Maria Xenochristou, Xiaoyuan Han, Camilo Espinosa, Kristen Rumer, Laura Peterson, Franck Verdonk, Dyani Gaudilliere, Eileen Tsai, Dorien Feyaerts, Jakob Einhaus, Kazuo Ando, Ronald J. Wong, Gerlinde Obermoser, Gary M. Shaw, David K. Stevenson, Martin S. Angst, and Brice Gaudilliere

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Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China, Fei Yu, Lanying Du, David M. Ojcius, Chungen Pan, and Shibo Jiang

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Banking on teeth – Stem cells and the dental office, Benjamin D. Zeitlin

Submissions from 2019

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Chlamydia pneumoniae is present in the dental plaque of periodontitis patients and stimulates an inflammatory response in gingival epithelial cells, Cássio Luiz Coutinho Almeida-da-Silva, Tamer Alpagot, Ye Zhu, Sonho Sierra Lee, Brian P. Roberts, Shu-Chen Hung, Norina Tang, and David M. Ojcius

Chlamydia pneumoniae is present in the dental plaque of periodontitis patients and stimulates an inflammatory response in gingival epithelial cells, Cássio Luiz Coutinho Almeida-da-Silva, Tamer Alpagot, Ye Zhu, S. S. Lee, Brian P. Roberts, Shu-Chen Hung, Norina Tang, and David M. Ojcius

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P2X7 receptor-mediated leukocyte recruitment and Porphyromonas gingivalis clearance requires IL-1β production and autocrine IL-1 receptor activation, Cássio Luiz Coutinho Almeida-da-Silva, Erivan S. Ramos-Junior, Ana Carolina Morandini, Gabrielle da Costa Rocha, Ygor Marinho, Augusto Shuiti Tamura, Kívia Queiroz de Andrade, Maria Bellio, Luiz Eduardo Baggio Savio, Julio Scharfstein, David M. Ojcius, and Robson Coutinho-Silva

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Association between periodontal pathogens and systemic disease, Fiona Q. Bui, Cássio Luiz Coutinho Almeida-da-Silva, Brandon Huynh, Alston Trinh, Jessica Liu, Jacob Woodward, Homer Asadi, and David M. Ojcius