A selection of scholarship from faculty members of the Department of Biomedical Sciences (BMS) at Arthur A. Dugoni School of Dentistry, University of the Pacific.

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Submissions from 2013

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Modulation of the Effects of Lung Immune Response on Bone Marrow by Oral Antigen Exposure, Pedro Xavier-Elsas, Cassio Luiz Coutinho Almeida-Da-Silva, L. Pinto, Túlio Queto, Bruno Marques Vieira, M. G. Aramha, Bianca De Luca, Daniela Masid-de-Brito, R. A. Luz, R. S. Lopes, R. Ferreira, and Maria Ignez C. Gaspar-Elsas

Characterizing a new population of adult mouse submandibular gland stem cells, Nan (Tori) Xiao

Presentation, Nan (Tori) Xiao

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A novel aldehyde dehydrogenase-3 activator (Alda-89) protects submandibular gland function from irradiation without accelerating tumor growth, Nan (Tori) Xiao, Hongbin Cao, Che-Hong Chen, Christina S. Kong, Rehan Ali, Cato Chan, Davud Sirjani, Edward Graves, Albert Koong, Amato Giaccia, Daria Mochly-Rosen, and Quynh-Thu Le

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Performance and leaching analysis of a novel coal sludge-based backfill material, Yuan Yao, Henghu Sun, Shushu Jiang, Rui Zhang, Dan Su, Chao Feng, and Xiaoyuan Han

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Botulinum Toxin Confers Radioprotection In Murine Salivary Glands, Y. Zeidan, Nan (Tori) Xiao, Hongbin Cao, C. Kong, Quynh-Thu Le, and D. Sirjani

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Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China, Lei Zhang, Jie Yan, David M. Ojcius, Huakun Lv, Ziping Miao, Yin Chen, Yanjun Zhang, and Jvying Yan

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Identification of Leptospira interrogans phospholipase C as a novel virulence factor responsible for intracellular free calcium ion elevation during macrophage death, Jing-Fang Zhao, Hong-Hu Chen, David M. Ojcius, Xin Zhao, Dexter Sun, Yu-Mei Ge, Lin-Li Zheng, Xu'ai Lin, Lan-Juan Li, and Jie Yan

Submissions from 2012

A Defect In Granulopoiesis In Perforin Deficient Mice, Cássio Luiz Coutinho Almeida-da-Silva, Pedro Xavier-Elsas, Daniela Masid-De-Brito, Túlio Queto, T. S.S. Vieira, and Maria Ignez Capella Gaspar-Elsas

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Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy, Daniele Andrade, Rafaela Serra, Erik Svensjö, Ana Paula C. Lima, Erivan Schnaider Ramos-Junior, Fabio S. Fortes, Ana Carolina Morandini, Verônica Morandi, Maria de N Soeiro, Herbert B. Tanowitz, and Julio Scharfstein

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Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection, Chang-Chieh Chen, Sheng-Hui Tsai, Chia-Chen Lu, Shiau-Ting Hu, Ting-Shu Wu, Tsung-Teng Huang, Najwane Saïd-Sadier, David M. Ojcius, and Hsin-Chih Lai

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Tumour inflammasome-derived IL-1b recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma, Lih-Chyang Chen, Li-Jie Wang, Nang-Ming Tsang, David M. Ojcius, Chia-Chen Chen, Chun-Nan OuYang, Chuen Hsueh, Ying Liang, Kai-Ping Chang, Chiu-Chin Chen, and Yu-Sun Chang

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Role of extracellular nucleotides in the immune response against intracellular bacteria and protozoan parasites, Robson Coutinho-Silva and David M. Ojcius

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Miconazole activity against Candida biofilms on acrylic discs, Barbara Dorocka-Bobkowska, Senait Gebremedhin, Nejat Düzgüneş, and Krystyna Konopka

Suppression Of Murine Granulopoiesis By Oral Allergen Pretreatment Of Sensitized/ Challenged, Maria Ignez Capella Gaspar-Elsas, Túlio Queto, Daniela Masid-De-Brito, Ricardo Alves Luz, L. Pinto, L. Franca B De, M. Aranha, Cássio Luiz Coutinho Almeida-da-Silva, R. Ferreira, Rodrigo Soares Lopes, P. Cauduro, Bruno Marques Vieira, and Pedro Xavier-Elsas

HIV-specific promoters to eliminate HIV-infected cells by gene therapy, Senait Gebremedhin, A. Au, Krystyna Konopka, M. Milnes, and Nejat Düzgüneş

A gene therapy approach to eliminate HIV-1-infected cells., Senait Gebremedhin, Amy Au, Krystyna Konopka, Matthew Milnes, and Nejat Düzgüneş

Candida biofilms on denture acrylic discs: effects of fluconazole and miconazole, Senait Gebremedhin, Krystyna Konopka, Barbara Dorocka-Bobkowska, and Nejat Düzgüneş

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The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages, Tsung-Teng Huang, David M. Ojcius, John Ding-E. Young, Yi-Hui Wu, Yun-Fei Ko, Tsui-Yin Wong, Cheng-Yeu Wu, Chia-Chen Lu, and Hsin-Chih Lai

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Metronomic Dosing of BH3 Mimetic Small Molecule Yields Robust Antiangiogenic and Antitumor Effects, Atsushi Imai, Benjamin David Zeitlin, Francesco Visioli, Zhihong Dong, Sudha Krishnamurthy, Marnie Emily Light, Frank Worden, Shaomeng Wang, and Jacques E. Nör

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Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol, Hsin-Chih Lai, Chih-Jung Chang, Chun-Hung Yang, Ya-Jing Hsu, Chang-Chieh Chen, Chuan-Sheng Lin, Yu-Huan Tsai, Tsung-Teng Huang, David M. Ojcius, Ying-Huang Tsai, and Chia-Chen Lu

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Mixed and Purified SCAPs: Similar Growth, Phenotypic and Differentiation Characteristics, Julian G. Leprince, Benjamin David Zeitlin, Miroslav Tolar, Anibal Diogenes, and Ove A. Peters

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Interactions between immune system and mesenchymal stem cells in dental pulp and periapical tissues, Julian G. Leprince, Benjamin David Zeitlin, Miroslav Tolar, and Ove A. Peters

Role of Endogenous glucocorticoids In The Regulation Of Eosinopoiesis In A Murine Model For Allergic Asthma, Daniela Masid-De-Brito, Pedro Xavier-Elsas, Ricardo Alves Luz, Túlio Queto, Cássio Luiz Coutinho Almeida-da-Silva, Rodrigo Soares Lopes, Bruno Marques Vieira, E. P. Dias, P. M.R. Silva, and Maria Ignez Capella Gaspar-Elsas

Interleukin (IL)-6, IL-8 and CXCL12 mRNA expression in human gingival and periodontal ligament fibroblasts is regulated by both MyD88 and TRAM, Ana Carolina Morandini, P. P. C. Souza, Erivan Schnaider Ramos-Junior, Carla Renata Sipert, Carlos Alberto Souza Costa, and Carlos Ferreira Santos

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Physicochemical and biological properties of biomimetic mineralo-protein nanoparticles formed spontaneously in biological fluids, Hsin-Hsin Peng, Cheng-Yeu Wu, David Young, Jan Martel, Andrew Young, David M. Ojcius, Yu-Hsiu Lee, and John Ding-E. Young

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Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells, Matthew A. Pettengill, Verissa W. Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, and David M. Ojcius

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Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X4 receptors, Matthew A. Pettengill, Camila Marques-da-Silva, Maria Luisa Avila, Verissa W. Lam, Ikechukwu Ollawa, Ali Abdul-Sater, Robson Coutinho-Silva, Georg Hacker, David M. Ojcius, and Suellen d'Arc dos Santos Oliveira

Mouse fibroblasts guide IL-23 induction by Porphyromonas gingivalis-stimulated Dendritic Cells in gingipain-dependent manner, Erivan Schnaider Ramos-Junior, C. Nascimento, Ana Carolina Morandini, J. Wergles, K. Nguyen, J. Potempa, and Julio Scharfstein

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Development of a humanized HLA-A2.1/DP4 transgenic mouse model and the use of this model to map HLA-DP4-restricted epitopes of HBV envelope protein, Zhitao Ru, Wenjun Xiao, Anthony Pajot, Zhihua Kou, Shihui Sun, Benard Maillere, Guangyu Zhao, David M. Ojcius, Yu-Chun Lone, and Yusen Zhou

Alarmins, inflammasomes and immunity, Najwane Saïd-Sadier and David M. Ojcius

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Titanium surfaces with nanotopography modulate cytokine production in cultured human gingival fibroblasts, Humberto Osvaldo Schwartz-Filho, Ana Carolina Morandini, Erivan Schnaider Ramos-Junior, Ryo Jimbo, Carlos Ferreira Santos, Elcio Marcantonio Jr., Ann Wennerberg, and Rosemary Adriana Chiérici Marcantonio

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Cytokine induction by Porphyromonas gingivalis depends on epithelial cell type, Pushpinder Sethi, Michael Yee, Nejat Düzgüneş, and Krystyna Konopka

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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis, Kenichi Shimada, Timothy R. Crother, Justin Karlin, Jargalsaikhan Dagvadori, Norika Chiba, Shuang Chen, V. Krishnan Ramanujan, Andrea J. Wolf, Laurent Vergnes, David M. Ojcius, Altan Rentsendorj, Mario Vargas, Candace Guerrero, Yinsheng Wang, Katherine A. Fitzgerald, David M. Underhill, Terrence Town, and Moshe Arditi

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Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-κB signaling pathways, Huan Wang, Yifei Hu, David M. Ojcius, X. Frank Yang, Chenglin Zhang, Shibiao Ding, Xu'ai Lin, and Jie Yan

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Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes, Li-Jie Wang, Chia-Wei Hsu, Chiu-Chin Chen, Ying Liang, Lih-Chyang Chen, David M. Ojcius, Ngan-Ming Tsang, Chuen Hsueh, Chih-Ching Wu, and Yu-Sun Chang

Characterizing a new population of adult mouse submandibular gland stem cells, Nan (Tori) Xiao, Yuan Lin, Maximillian Diehn, and Quynh-Thu Le

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Porphyromonas gingivalis stimulates IL-18 secretion in human monocytic THP-1 cells, Michael Yee, Andrew Kim, Tamer Alpagot, Nejat Düzgüneş, and Krystyna Konopka

Cytotoxicity of liposomal C6-ceramide in oral squamous cell carcinoma cells, Michael Yee, S. Sutter, Nasser Said-Al-Naief, P. Plowman, and Nejat Düzgüneş

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Responsive Angiogenic Implanted Network (RAIN) Droplet: A Novel Angiogenesis Assay, Benjamin David Zeitlin, Zhihong Dong, and Jacques E. Nör

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3D model of angiogenesis as a platform for analysis of endothelial cell derived microvesicles, Benjamin David Zeitlin and Jacques E. Nör

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Rapid and sensitive identification of RNA from the emerging pathogen, coxsackievirus A6, Lei Zhang, Xinying Wang, Yanjun Zhang, Liming Gong, Haiyan Mao, Cen Feng, David M. Ojcius, and Jie Yan

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The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals, Lei Zhang, Chenglin Zhang, David M. Ojcius, Dexter Sun, Jinfang Zhao, Xu'ai Lin, Liwei Li, Lanjuan Li, and Jie Yan

Submissions from 2011

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A novel aldehyde dehydrogenase-3 activator leads to adult salivary stem cell enrichment in vivo, Alice Banh, Nan (Tori) Xiao, Hongbin Cao, Che-Hong Chen, Peiwen Kuo, Trevor Krakow, Brindha Bavan, Brian Khong, Mike Yao, Chi Ha, Michael J. Kaplan, Davud Sirjani, Kristin Jensen, Christina S. Kong, Daria Mochly-Rosen, Albert C. Koong, and Quynh-Thu Le

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Evaluation of the use of an injectable matrix for tissue engineering of dental pulp, Bruno Das Neves Cavalcanti, Benjamin David Zeitlin, and Jacques E. Nör

C-reactive protein in type 2 diabetes and denture stomatitis, Barbara Dorocka-Bobkowska, D. Zozulinska-Ziolkiewicz, B. Wierusz-Wysocka, Nejat Düzgüneş, and Krystyna Konopka

Funding biomedical research, Nejat Düzgüneş

Cationic polymer-mediated gene delivery to oral cancer cells, Senait Gebremedhin, F. Martinez, Krystyna Konopka, and Nejat Düzgüneş

The Effects of Streptozotocin-induced Diabetes and Gender on the Rat Aortic Endothelial Function, Xiaoyuan Han, Leigh Anderson, and Roshanak Rahimian

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Editorial [Hot Topic: Physico-chemical Approach to Targeting Phenomena (Guest Editors: Sadao Hirota and Nejat Duzgunes)], Sadao Hirota and Nejat Düzgüneş

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Altered pathogenicity for seasonal influenza virus by single reassortment of the RNP genes derived from the 2009 pandemic influenza virus, Erh-Fang Hsieh, Sue-Jane Lin, Chee-Keng Mok, Guang-Wu Chen, Chih-Heng Huang, Yeau-Ching Wang, Tzu-Chun Chen, Chi-Jene Chen, David M. Ojcius, and Shin-Ru Shih

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Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin, Tsung-Teng Huang, Fu-Guo Liu, Chia-Fong Wei, Chia-Chen Lu, Chang-Chieh Chen, Hung-Chi Lin, David M. Ojcius, and Hsin-Chih Lai

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Porphyromonas gingivalis stimulates interleukin-8 secretion in human oral epithelial cells, Shawn Kim, Michael Yee, T. Alpagot, Nejat Düzgüneş, and Krystyna Konopka

HIV-specific transgene expression via progressively truncated Tat-Responsive LTR promoters, J. King, Senait Gebremedhin, Krystyna Konopka, M. Milnes, and Nejat Düzgüneş

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Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages, Camila Marques-da-Silva, Geoffrey Burnstock, David M. Ojcius, and Robson Coutinho-Silva

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Infection with Leishmania amazonensis upregulates purinergic receptor expressionand induces host-cell susceptibility to UTP-mediated apoptosis, Camila Marques-da-Silva, M. M. Chaves, S. P. Chaves, V. R. Figliuolo, J. R. Meyer-Fernandes, S. Corte-Real, C. Lameu, H. Ulrich, David M. Ojcius, B. Rossi-Bergmann, and Robson Coutinho-Silva

Role of Endogenous Glucocorticoids In the Regulation of Eosinopoiesis In A Murine Model For Allergic Asthma, Daniela Masid-De-Brito, Pedro Xavier-Elsas, Ricardo Alves Luz, Cássio Luiz Coutinho Almeida-da-Silva, Túlio Queto, and Maria Ignez Capella Gaspar-Elsas

Role Of Endogenous Glucocorticoids In The Regulation Of Eosinopoiesis In A Murine Model For Allergic Asthma, Daniela Masid-De-Brito, Pedro Xavier-Elsas, Ricardo Alves Luz, Túlio Queto, Cássio Luiz Coutinho Almeida-da-Silva, Rodrigo Soares Lopes, Bruno Marques Vieira, and Maria Ignez Capella Gaspar-Elsas

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Periodontal ligament and gingival fibroblasts participate in the production of TGF-β, interleukin (IL)-8 and IL-10, Ana Carolina Morandini, Carla Renata Sipert, Erivan Schnaider Ramos-Junior, Daniel Thomas Brozoski, and Carlos Ferreira Santos

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D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma, S. D. Nandedkar, D. Weihrauch, H. Xu, Y. Shi, T. Feroah, W. Hutchins, D. A. Rickaby, Nejat Düzgüneş, C. A. Hillery, K. S. Konduri, and K. A. Pritchard

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Comparative analysis of two colorimetric assays in dental pulp cell density. International Endodontic Journal, Fernanda Nedel, Fabiana Naomi Soki, Marcus Cristian Muniz Conde, Benjamin David Zeitlin, Sandra Beatriz Chaves Tarquinio, Jacques E. Nör, Fabiana Kömmling Seixas, and Flavio F. Demarco

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Serum-derived nanoparticles: de novo generation and growth in vitro, and internalization by mammalian cells in culture, Hsin-Hsin Peng, Jan Martel, Yu-Hsiu Lee, David M. Ojcius, and John Ding-E. Young

Toll-like Receptor 4(TLR4) is expressed in Pulp Fibroblasts After Stimulation with Candida albicans, C. R. Pinheiro, Carla Renata Sipert, Thaís Helena Gasparoto, C. E. Oliveira, M. S. Silva, Ana Carolina Morandini, Gustavo P. Garlet, Carlos Ferreira Santos, J. S. Silva, and Ana Paula Campanelli

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Tooth Slice/Scaffold Model of Dental Pulp Tissue Engineering, Vivien Thiemy Sakai, Mabel Mariela Cordeira, Zhihong Dong, Zhaocheng Zhang, Benjamin David Zeitlin, and Jacques E. Nör

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Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection, Claire Séror, Marie-Therese Melki, Frederic Subra, Syed Qasim Raza, Marlene Bras, Hela Saïdi, Roberta Nardacci, Laurent Voisin, Audrey Paoletti, Frederic Law, Isabelle Martins, Alessandra Amendola, Ali A. Abdul-Sater, Fabiola Ciccosanti, Olivier Delelis, Florence Niedergang, Sylvain Thierry, Najwane Said-Sadier, Christophe Lamaze, Didier Métivier, Jerome Estaquier, Gian Maria Fimia, Laura Falasca, Rita Casetti, Nazanine Modjtahedi, Jean M. Kanellopoulos, Jean-Francois Mouscadet, David M. Ojcius, Mauro Piacentini, Marie-Lise Gougeon, Guido Kroemer, and Jean-Luc Perfetini

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Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection, Kenichi Shimada, Timothy R. Crother, Justin Karlin, Shuang Chen, Norika Chiba, V. Krishnan Ramanujan, Laurent Vergnes, David M. Ojcius, and Moshe Arditi

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Hypervirulent Chlamydia trachomatis clinical strain is a recombinant between lymphogranuloma venereum (L(2)) and D lineages, Naraporn Somboonna, Raymond Wan, David M. Ojcius, Matthew A. Pettengill, Sandeep J. Joseph, Alexander Chang, Ray Hsu, Timothy D. Read, and Deborah Dean

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Epithelial cell type affects interleukin-6 response to Porphyromonas gingivalis, Michael Yee, T. Alpagot, Nejat Düzgüneş, and Krystyna Konopka

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Small-Molecule Inhibitors Reveal a New Function for Bcl-2 as a Pro-angiogenic Signaling Molecule, Benjamin David Zeitlin and Jacques E. Nör

Submissions from 2010

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Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1, Ali A. Abdul-Sater, Najwene Saïd-Sadier, Verissa M. Lam, Bhavni Singh, Matthew A. Pettengill, Fraser Soares, Ivan Tattoli, Simone Lipinski, Stephen E. Girardin, Philip Rosenstiel, and David M. Ojcius

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Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome, Ali A. Abdul-Sater, Najwene Saïd-Sadier, Eduardo V. Padilla, and David M. Ojcius

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Puramatrix: An injectable scaffold for dental pulp tissue engineering., Bruno Das Neves Cavalcanti, Benjamin David Zeitlin, and Jacques E. Nör

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Effects of Morphogen and Scaffold Porogen on the Differentiation of Dental Pulp Stem Cells, Flavio F. Demarco, Luciano Casagrande, Zhaocheng Zhang, Zhihong Dong, Sandra Beatriz Chaves Tarquinio, Benjamin David Zeitlin, Songtao Shi, Anthony J. Smith, and Jacques E. Nör

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Lectins and T-20, but not neutralizing antibodies, inhibit HIV-1 Env-mediated syncytium formation between Clone69T1RevEnv and SupT1 cells monitored by fluorescence microscopy, Nejat Düzgüneş, Michael Yee, Jan Balzarini, and Krystyna Konopka

Cell-penetrating peptides enhance gene delivery by lipid-DNA complexes, J. Fountain, Senait Gebremedhin, Krystyna Konopka, and Nejat Düzgüneş

Overcoming the lipofection resistance of oral cancer cells: polyplexes and adenoviruses, Senait Gebremedhin, Krystyna Konopka, I. Ulasov, M. Lesniak, and Nejat Düzgüneş

Efficient gene delivery to oral cancer cells by polyethylenimine-DNA complexes, Senait Gebremedhin, F. Martinez, J. Fountain, Krystyna Konopka, and Nejat Düzgüneş

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From combinatorial peptide selection to drug prototype (I): Targeting the vascular endothelial growth factor receptor pathway, Ricardo Jose Giordano, Marina Cardo-Vila, Ahmad Salameh, Cristiane D. Anobom, Benjamin David Zeitlin, David H. Hawke, Ana Paula Valente, Fabio C. L. Almeida, Jacques E. Nör, Richard L. Sidman, and Renata Pasqualini

Cytokine responses of oral epithelial cells exposed to Porphyromonas gingivalis, Shawn Kim, Michael Yee, T. Alpagot, Nejat Düzgüneş, and Krystyna Konopka

Gene expression mediated by progressively truncated HIV-LTR promoters and HIV-Tat: How to kill HIV-infected cells, J. King, Senait Gebremedhin, Krystyna Konopka, Nejat Düzgüneş, and M. Milnes

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Susceptibility of Candida biofilms to histatin 5 and fluconazole, Krystyna Konopka, Barbara Dorocka-Bobkowska, Senait Gebremedhin, and Nejat Düzgüneş

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Susceptibility of Candida biofilms to histatin-5 and fluconazole, Krystyna Konopka, Barbara Dorocka-Bobkowska, Senait Gebremedhin, J. Wilson, and Nejat Düzgüneş

Cationic liposome enhancement of adenoviral vectors for gene delivery to OSCC, G. Lim, Senait Gebremedhin, J. Ouellette, I. Ulasov, M. Lesniak, Krystyna Konopka, and Nejat Düzgüneş

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Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin, Shijun Li, David M. Ojcius, Sumei Liao, Liwei Li, Feng Xue, Haiyan Dong, and Jie Yan

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Differential production of macrophage inflammatory protein-1alpha, stromal-derived factor-1, and IL-6 by human cultured periodontal ligament and gingival fibroblasts challenged with lipopolysaccharide from P. gingivalis, Ana Carolina Morandini, Carla Renata Sipert, Thaís Helena Gasparoto, Sebastião Luiz A. Greghi, Euloir Passanezi, Maria Lucia R. Rezende, Adriana Campos Passanezi Sant'ana, Ana Paula Campanelli, Gustavo P. Garlet, and Carlos Ferreira Santos

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Microbes and Infection: past, present and future, David M. Ojcius and Stefan H. E. Kaufmann

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Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase, Najwane Saïd-Sadier, Eduardo V. Padilla, Gordon Langsley, and David M. Ojcius

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Gene delivery by lipoplexes and polyplexes, Conchita Tros de Ilarduya, Yan Sun, and Nejat Düzgüneş

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Thrombospondin 1 accelerates synaptogenesis in hippocampal neurons through neuroligin 1, Junyu Xu, Nan (Tori) Xiao, and Jun Xia

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Effect of crocetin on blood pressure restoration and synthesis of inflammatory mediators in heart after hemorrhagic shock in anesthetized rats, Junling Yan, Zhi Yu Qian, Liang Sheng, Bohua Zhao, Lina Yang, Hui Ji, Xiaoyuan Han, and Rong Zhang

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Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells, L. Yao, C. Jermanus, B. Barbetta, C. Choi, Philippe Verbeke, David M. Ojcius, and Özlem Yilmaz

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Porphyromonas gingivalis stimulates IL-18 secretion in monocytic THP-1 cells, Michael Yee, A. Kim, Nejat Düzgüneş, T. Alpagot, and Krystyna Konopka

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HIV-1 Env-mediated membrane fusion monitored by fluorescence microscopy of syncytium formation between Clone69T1RevEnv and SupT1 cells, Michael Yee, Krystyna Konopka, Jan Balzarini, and Nejat Düzgüneş

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ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis, Özlem Yilmaz, Ali A. Abdul-Sater, L. Yao, T. Koutouzis, Matthew A. Pettengill, and David M. Ojcius

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Metronomic small molecule inhibitor of Bcl-2 (TW-37) is antiangiogenic and potentiates the antitumor effect of ionizing radiation, Benjamin David Zeitlin, Aaron C. Spalding, Marcia S. Campos, Naoki Ashimori, Zhihong Dong, Shaomeng Wang, Theodore S. Lawrence, and Jacques E. Nör

Submissions from 2009

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Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis, Ali A. Abdul-Sater, Evonne Koo, Georg Hacker, and David M. Ojcius

Inflammasomes bridge signalling between pathogen identification and the immune response, Ali A. Abdul-Sater, Najwene Saïd-Sadier, David M. Ojcius, O. Yilmaz, and Kathy A. Kelly

Anti-tumor and anti-angiogenic effect of TW37 and Cisplatin combination therapy, Naoki Ashimori, Benjamin David Zeitlin, Kristy Warner, and Jacques E. Nör

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TW-37, a small-molecule inhibitor of Bcl-2, mediates S-phase cell cycle arrest and suppresses head and neck tumor angiogenesis, Naoki Ashimori, Benjamin David Zeitlin, Zhaocheng Zhang, Kristy Warner, Ilan M. Turkienicz, Aaron C. Spalding, Theodoros N. Teknos, Shaomeng Wang, and Jacques E. Nör

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The oral microbiota: living with a permanent guest, Maria Avila, David M. Ojcius, and Ozlem Yilmaz