Submissions from 2010
Puramatrix: An injectable scaffold for dental pulp tissue engineering., Bruno Das Neves Cavalcanti, Benjamin David Zeitlin, and Jacques E. Nör
Effects of Morphogen and Scaffold Porogen on the Differentiation of Dental Pulp Stem Cells, Flavio F. Demarco, Luciano Casagrande, Zhaocheng Zhang, Zhihong Dong, Sandra Beatriz Chaves Tarquinio, Benjamin David Zeitlin, Songtao Shi, Anthony J. Smith, and Jacques E. Nör
Lectins and T-20, but not neutralizing antibodies, inhibit HIV-1 Env-mediated syncytium formation between Clone69T1RevEnv and SupT1 cells monitored by fluorescence microscopy, Nejat Düzgüneş, Michael Yee, Jan Balzarini, and Krystyna Konopka
Cell-penetrating peptides enhance gene delivery by lipid-DNA complexes, J. Fountain, Senait Gebremedhin, Krystyna Konopka, and Nejat Düzgüneş
Overcoming the lipofection resistance of oral cancer cells: polyplexes and adenoviruses, Senait Gebremedhin, Krystyna Konopka, I. Ulasov, M. Lesniak, and Nejat Düzgüneş
Efficient gene delivery to oral cancer cells by polyethylenimine-DNA complexes, Senait Gebremedhin, F. Martinez, J. Fountain, Krystyna Konopka, and Nejat Düzgüneş
From combinatorial peptide selection to drug prototype (I): Targeting the vascular endothelial growth factor receptor pathway, Ricardo Jose Giordano, Marina Cardo-Vila, Ahmad Salameh, Cristiane D. Anobom, Benjamin David Zeitlin, David H. Hawke, Ana Paula Valente, Fabio C. L. Almeida, Jacques E. Nör, Richard L. Sidman, and Renata Pasqualini
Cytokine responses of oral epithelial cells exposed to Porphyromonas gingivalis, Shawn Kim, Michael Yee, T. Alpagot, Nejat Düzgüneş, and Krystyna Konopka
Gene expression mediated by progressively truncated HIV-LTR promoters and HIV-Tat: How to kill HIV-infected cells, J. King, Senait Gebremedhin, Krystyna Konopka, Nejat Düzgüneş, and M. Milnes
Susceptibility of Candida biofilms to histatin 5 and fluconazole, Krystyna Konopka, Barbara Dorocka-Bobkowska, Senait Gebremedhin, and Nejat Düzgüneş
Susceptibility of Candida biofilms to histatin-5 and fluconazole, Krystyna Konopka, Barbara Dorocka-Bobkowska, Senait Gebremedhin, J. Wilson, and Nejat Düzgüneş
Cationic liposome enhancement of adenoviral vectors for gene delivery to OSCC, G. Lim, Senait Gebremedhin, J. Ouellette, I. Ulasov, M. Lesniak, Krystyna Konopka, and Nejat Düzgüneş
Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin, Shijun Li, David M. Ojcius, Sumei Liao, Liwei Li, Feng Xue, Haiyan Dong, and Jie Yan
Differential production of macrophage inflammatory protein-1alpha, stromal-derived factor-1, and IL-6 by human cultured periodontal ligament and gingival fibroblasts challenged with lipopolysaccharide from P. gingivalis, Ana Carolina Morandini, Carla Renata Sipert, Thaís Helena Gasparoto, Sebastião Luiz A. Greghi, Euloir Passanezi, Maria Lucia R. Rezende, Adriana Campos Passanezi Sant'ana, Ana Paula Campanelli, Gustavo P. Garlet, and Carlos Ferreira Santos
Microbes and Infection: past, present and future, David M. Ojcius and Stefan H. E. Kaufmann
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase, Najwane Saïd-Sadier, Eduardo V. Padilla, Gordon Langsley, and David M. Ojcius
Gene delivery by lipoplexes and polyplexes, Conchita Tros de Ilarduya, Yan Sun, and Nejat Düzgüneş
Thrombospondin 1 accelerates synaptogenesis in hippocampal neurons through neuroligin 1, Junyu Xu, Nan (Tori) Xiao, and Jun Xia
Effect of crocetin on blood pressure restoration and synthesis of inflammatory mediators in heart after hemorrhagic shock in anesthetized rats, Junling Yan, Zhi Yu Qian, Liang Sheng, Bohua Zhao, Lina Yang, Hui Ji, Xiaoyuan Han, and Rong Zhang
Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells, L. Yao, C. Jermanus, B. Barbetta, C. Choi, Philippe Verbeke, David M. Ojcius, and Özlem Yilmaz
Porphyromonas gingivalis stimulates IL-18 secretion in monocytic THP-1 cells, Michael Yee, A. Kim, Nejat Düzgüneş, T. Alpagot, and Krystyna Konopka
HIV-1 Env-mediated membrane fusion monitored by fluorescence microscopy of syncytium formation between Clone69T1RevEnv and SupT1 cells, Michael Yee, Krystyna Konopka, Jan Balzarini, and Nejat Düzgüneş
ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis, Özlem Yilmaz, Ali A. Abdul-Sater, L. Yao, T. Koutouzis, Matthew A. Pettengill, and David M. Ojcius
Metronomic small molecule inhibitor of Bcl-2 (TW-37) is antiangiogenic and potentiates the antitumor effect of ionizing radiation, Benjamin David Zeitlin, Aaron C. Spalding, Marcia S. Campos, Naoki Ashimori, Zhihong Dong, Shaomeng Wang, Theodore S. Lawrence, and Jacques E. Nör
Submissions from 2009
Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis, Ali A. Abdul-Sater, Evonne Koo, Georg Hacker, and David M. Ojcius
Inflammasomes bridge signalling between pathogen identification and the immune response, Ali A. Abdul-Sater, Najwene Saïd-Sadier, David M. Ojcius, O. Yilmaz, and Kathy A. Kelly
Anti-tumor and anti-angiogenic effect of TW37 and Cisplatin combination therapy, Naoki Ashimori, Benjamin David Zeitlin, Kristy Warner, and Jacques E. Nör
TW-37, a small-molecule inhibitor of Bcl-2, mediates S-phase cell cycle arrest and suppresses head and neck tumor angiogenesis, Naoki Ashimori, Benjamin David Zeitlin, Zhaocheng Zhang, Kristy Warner, Ilan M. Turkienicz, Aaron C. Spalding, Theodoros N. Teknos, Shaomeng Wang, and Jacques E. Nör
The oral microbiota: living with a permanent guest, Maria Avila, David M. Ojcius, and Ozlem Yilmaz
The P2X7 receptor and intracellular pathogens: a continuing struggle, Robson Coutinho-Silva, Gladys Corrêa, Ali A. Abdul-Sater, and David M. Ojcius
A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis, Robert C. Doebele, Frank Thilo Schulze-Hoepfner, Jia Hong, Alexandre Chlenski, Benjamin David Zeitlin, Kushboo Goel, Suzana Gomes, Yuru Liu, Mark K. Abe, Jacques E. Nör, and Mark W. Lingen
AmBisome and amphotericin B inhibit the initial adherence of Candida albicans to human epithelial cell lines, but do not cause yeast detachment, Barbara Dorocka-Bobkowska, Nejat Düzgüneş, and Krystyna Konopka
Comparison of Effect on Isoproterenol-induced Myocardial Injury Between Crocetin and Crocin / 比较西红花酸和西红花苷对异丙肾上腺素损伤心肌的作用, Xiaoyuan Han, Zhiyu Qian, Zhang Rong, Zhen Chen, Junling Yan, and Lina Yang
Leptospira interrogans induces apoptosis in macrophages via caspase-8- and -3-dependent pathways, Dandan Jin, David M. Ojcius, Dexter Sun, Haiyan Dong, Yihui Luo, Yafei Mao, and Jie Yan
Inflammatory cytokine secretion by THP-1 cells exposed to Porphyromonas gingivalis, A. Kim, Michael Yee, Nejat Düzgüneş, T. Alpagot, and Krystyna Konopka
Inflammatory cytokine secretion by THP-1 cells exposed to Porphyromonas gingivalis, A. Kim, Michael Yee, Nejat Düzgüneş, T. Alpagot, and Krystyna Konopka
Correlation between the levels of survivin and survivin promoter-driven gene expression in cancer and non-cancer cells, Krystyna Konopka, Christopher Spain, Allison Yen, Nathan Overlid, Senait Gebremedhin, and Nejat Düzgüneş
Gene delivery to oral cancer cells by nonviral vectors: why some cells are resistant to transfection., Cassidy Lavorini-Doyle, Senait Gebremedhin, Krystyna Konopka, and Nejat Düzgüneş
Intracellular fate of non-viral vectors in oral cancer cells, Cassidy Lavorini-Doyle, Senait Gebremedhin, Krystyna Konopka, and Nejat Düzgüneş
Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai, Sumei Liao, Ai-Hua Sun, David M. Ojcius, Senlin Wu, Jinfang Zhao, and Jie Yan
Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity, Dongjiao Luo, Feng Xue, David M. Ojcius, Jinfang Zhao, Ya-Fei Mao, Liwei Li, Xu'ai Lin, and Jie Yan
An iterative strategy combining biophysical criteria and duration hidden Markov) models for structural predictions of Chlamydia trachomatis s66 promoters, Ronna R. Mallios, David M. Ojcius, and David H. Ardell
Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response, S. Neves, Henrique Faneca, S. Bertin, Krystyna Konopka, Nejat Düzgüneş, V. Pierrefite-Carle, S. Simões, and M. C. Pedroso De Lima
Chikungunya fever: re-emergence of an old disease, Lisa F. P. Ng and David M. Ojcius
Enhancing gene delivery to cancer cells by transferrin and EGF, J. Ouellette, Senait Gebremedhin, Krystyna Konopka, and Nejat Düzgüneş
The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope, Jean-Luc Perfettini, Roberta Nardacci, C. Séror, M. Bourouba, F. Subra, L. Gros, Gwenola Manic, A. Amendola, P. Masdehors, F. Rosselli, David M. Ojcius, C. Auclair, H. de Thé, M. L. Gougeon, M. Piacentini, and G. Kroemer
The danger signal adenosine induces persistence of chlamydial infection through stimulation of A2b receptors, Matthew A. Pettengill, Verissa W. Lam, and David M. Ojcius
Differential production of CXCL12 by Cultured human dental pulp and gingival fibroblasts challenged by Porphyromonas gingivalis LPS and Escherichia coli LPS, Carla Renata Sipert, Ana Carolina Morandini, S. H. P. Oliveira, Ana Paula Campanelli, and Carlos Ferreira Santos
Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNg in human epithelial cells, L. Welter-Stahl, C. M. da Silva, Julieta Schachter, Pedro M. Persechini, H. S. Souza, David M. Ojcius, and Robson Coutinho-Silva
Effects of antifungals and histatin 5 on Candida albicans biofilms, J. Wilson, Senait Gebremedhin, Nejat Düzgüneş, and Krystyna Konopka
PICK1 deficiency causes male infertility in mice by disrupting acrosome formation, Nan (Tori) Xiao, Chuen Kam, Chong Shen, Wenying Jin, Junqi Wang, Kwong Man Lee, Liwen Jiang, and Jun Xia
HIV-1 Env-mediated cell-cell fusion is inhibited by lectins and peptides, but not by antibodies that inhibit infection, Michael Yee, Krystyna Konopka, Jan Balzarini, and Nejat Düzgüneş
Inhibition of Vascular Endothelial Growth Factor Receptor-1/Wnt/{beta}-catenin Crosstalk Leads to Tumor Cell Death, Benjamin David Zeitlin, Lee M. Ellis, and Jacques E. Nör
Comparison of the effects of crocetin and crocin on myocardial injury in rats, Rong Zhang, Zhi Yu Qian, Xiaoyuan Han, Zhen Chen, Jun Ling Yan, and A. Hamid
Submissions from 2008
Susceptibility of Chlamydia trachomatis to the excipient hydroxy-ethylcellulose: pH and concentration dependence of antimicrobial activity, Ali A. Abdul-Sater, David M. Ojcius, and M. P. Meyer
The association between gingival crevicular fluid TGF-β1 levels and periodontal status in HIV-1+ patients, Tamer Alpagot, Krystyna Konopka, Mouchumi Bhattacharyya, S. Gebremedhin, and Nejat Düzgüneş
The book reopened on infectious diseases, Maria Avila, Najwane Said, and David M. Ojcius
Oral epithelial cells exposed to Porphyromonas gingivalis: Analysis of genes relevant to periodontal disease, B. Behdad, V. Suzara, and Nejat Düzgüneş
Epac/Rap1 inhibit endothelial cell chemotaxis and angiogenesis via induction of Thrombospondin-1, Robert C. Doebele, Frank Thilo Schulze-Hoepfner, Alexandre Chlenski, Kushboo Goel, Jia Hong, Yuru Liu, Mark K. Abe, Mark W. Lingen, Benjamin David Zeitlin, Jacques E. Nör, and Marsha Rich Rosner
Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein, Haiyan Dong, Ye Hu, Feng Xue, Dexter Sun, David M. Ojcius, Yafei Mao, and Jie Yan
Sitimagene ceradenovec, a gene therapeutic for the treatment of glioma, Nejat Düzgüneş
Longitudinal evaluation of GCF interleukin-18 and Periodontitis in HIV+ patients, M. Hashimoto, T. Alpagot, Mouchumi Bhattacharyya, Krystyna Konopka, Senait Gebremedhin, and Nejat Düzgüneş
Survivin promoter-driven gene expression in cancer and non-cancer cells, Krystyna Konopka, Christopher Spain, Allison Yen, Nathan Overlid, Senait Gebremedhin, and Nejat Düzgüneş
Transferrin-lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in a murine model, Sílvia S. Neves, Henrique Faneca, Samuel Bertin, Krystyna Konopka, Nejat Düzgüneş, Valérie Pierrefite-Carle, Sérgio P. Simões, and Maria C. Pedroso de Lima
Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease, Stefan A. Paschen, Jan G. Christian, Juliane Vier, Franziska Schmidt, Axel Walch, David M. Ojcius, and Georg Hacker
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia, Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frederic Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M. Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, Jose R. Regueiro, Hughes de Thé, Marie-Lise Gougeon, Mauro Piacentini, and Guido Kroemer
L’Apoptose, J. L. Perfettini, David M. Ojcius, and G. Kroemer
Recombinant SpaO and H1a as immunogens for protection of mice from lethal infection with Salmonella paratyphi A: implications for rational design of typhoid fever vaccines, Ping Ruan, Xiao-Ping Xia, Dexter Sun, David M. Ojcius, Ya-Fei Yao, Wen-Yue Yue, and Jie Yan
Use of platelet-rich plasma (PRP ) in combination with sub- epithelial connective graft for root coverage in smoker patient : case report, S. Salmeron, Ana Carolina Morandini, E. A. Figueira, Adriana Campos Passanezi Sant'ana, M. L. R. Rezende, and S. L. A. Greghi
Enzastaurin, an inhibitor of PKC beta, Enhances Antiangiogenic Effects and Cytotoxicity of Radiation against Endothelial Cells., Aaron C. Spalding, Benjamin David Zeitlin, Kari Wilder-Romans, Mary Ellen Davis, Jacques E. Nör, Theodore S. Lawrence, and Edgar Ben-Josef
The association between GCF VEGF and periodontitis in HIV+ patients, E. Unger, T. Alpagot, Mouchumi Bhattacharyya, Krystyna Konopka, Senait Gebremedhin, and Nejat Düzgüneş
ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X(7)-mediated host-cell apoptosis, Özlem Yilmaz, L. Yao, K. Maeda, T. M. Rose, E. L. Lewis, M. Duman, R. J. Lamont, and David M. Ojcius
Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development, Songmin Ying, Matthew A. Pettengill, E. Ray Latham, Axel Walch, David M. Ojcius, and Georg Hacker
Expanding circle of inhibition: small-molecule inhibitors of Bcl-2 asanticancer cell and antiangiogenic agents, Benjamin David Zeitlin, Isaac J. Zeitlin, and Jacques E. Nör
Submissions from 2007
Longitudinal evaluation of prostaglandin E2 (PGE2) and periodontal status in HIV+ patients, Tamer Alpagot, John Remien, Mouchumi Bhattacharyya, Krystyna Konopka, William Lundergan, and Nejat Düzgüneş
The relationship between TGF-beta and periodontal status in HIV+ patients, T. Alpagot, Krystyna Konopka, Mouchumi Bhattacharyya, and Nejat Düzgüneş
The role of P2 receptors in controlling infections by intracellular pathogens, Robson Coutinho-Silva, Christiane Monteiro da Cruz, Pedro M. Persechini, and David M. Ojcius
ATP activates a Reactive Oxygen Species-dependent oxidative stress response and secretion of pro-inflammatory cytokines in macrophages, Christiane M. Cruz, Alessandra Rinna, Henry Jay Forman, Ana L. M. Ventura, Pedro M. Persechini, and David M. Ojcius
Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally-infected mice, Toni Darville, Lynn Welter-Stahl, Christiane Cruz, Ali Abdul-Sater, Charles W. Andrews Jr., and David M. Ojcius
Activated Epac and Rap1 are Novel Inhibitors of Tumor Angiogenesis, Robert C. Doebele, Jia Hong, Mark W. Lingen, Benjamin David Zeitlin, Jacques E. Nör, Yuru Liu, Mark K. Abe, and Marsha Rich Rosner
Level of endothelial cell apoptosis required for a significant decrease in microvessel density, Zhihong Dong, Benjamin David Zeitlin, Wenying Y. Song, Qinghua H. Sun, Elisabeta Karl, David M. Spencer, Harsh Vardhan Jain, Trachette L. Jackson, Gabriel Nunez, and Jacques E. Nör
A new paradigm for NIH grants, Nejat Düzgüneş
Serum-resistant lipopolyplexes for gene delivery to liver tumour cells, Leire García, Maria Buñuales, Nejat Düzgüneş, and Conchita Tros de Ilarduya
HIV-1 envelope glycoprotein-mediated membrane fusion monitored by fluorescence microscopy, A. Ghandi, Nathan Overlid, Krystyna Konopka, and Nejat Düzgüneş
Bcl-2 orchestrates a cross-talk between endothelial and tumor cells that promotes tumor growth, Tomoatsu Kaneko, Zhaocheng Zhang, Maria G. Mantellini, Mark W. Lingen, Robert M. Strieter, Gabriel Nunez, and Jacques E. Nör
The effect of daily apolipoprotein A-I mimetic therapy on T15-type autoantibodies against oxidized phosphatidylcholine in a murine model of asthma, Kameswari S. Konduri, Sandhya D. Nandedkar, D. Weilrauch, D. A. Rickaby, Nejat Düzgüneş, and K. A. Pritchard
Comparison of invasion of fibroblasts and macrophages by high- and low-virulence Leptospira strains: colonization of the host-cell nucleus and induction of necrosis by the virulent strain, L. Li, David M. Ojcius, and J. Yan
Expression of recombinant proteins in Pichia pastoris, Pingzuo Li, Anukanth Anumanthan, Xiu Gong Gao, Kuppusamy Ilangovan, Vincent V. Suzara, Nejat Düzgüneş, and V. Renugopalakrishnan
The Th1 immune response against HIV-1 Gag p24-derived peptides in mice expressing HLA-A02.01 and HLA-DR1, Anthony Pajot, Aurelie Schnuriger, Arnaud Moris, Audrey Rodallec, David M. Ojcius, Brigitte Austran, Francois A. Lemonnier, and Yu-Chun Lone
Liposomes inhbit uptake of bitter tastants into cultured epithelial cells, T. Preston, Diana Flasher, Shlomo Nir, and Nejat Düzgüneş
Murine survivin promoter-driven gene expression in cancer and non-tumor cells, Christopher Spain, Nathan Overlid, F. Li, Nejat Düzgüneş, and Krystyna Konopka
Targeting gene transfer vectors to oral squamous cell carcinoma cells, A. Streeter, Nathan Overlid, Krystyna Konopka, and Nejat Düzgüneş
Correlation between infections with different genotypes of human cytomegalovirus and Epstein-Barr virus in subgingival samples and the periodontal status of patients, Yan-Min Wu, Jie Yan, David M. Ojcius, Li-Li Chen, Zhi-Yuan Gu, and Jian-Peng Pan
Survivin promoter-driven gene expression in human oral cancer cells, Allison Yen, Nathan Overlid, F. Li, Nejat Düzgüneş, and Krystyna Konopka
Host-cell survival and death during Chlamydia infection, Songmin Ying, Matthew A. Pettengill, David M. Ojcius, and Georg Hacker
Submissions from 2006
Rap1 Activators are Novel Anti-Angiogenic Agents, Robert C. Doebele, Mark W. Lingen, Jacques E. Nör, Diane June Rodi, Jia Hong, Benjamin David Zeitlin, Wei-Jen Tang, and Marsha Rich Rosner
Anti-tumour activity in non-small cell lung cancer models and toxicity profiles for novel ruthenium(II) based organo-metallic compounds, Sylvie M. Guichard, Roderick W. Else, Benjamin David Zeitlin, Morwenna Muir, Michael Dodds, Heinz-Herbert Fiebig, Peter J. Sadler, and Duncan I. Jodrell
Effect of prolonged budesonide therapy on IL-4, IL-5, and IL-10 in a murine model of asthma, Kameswari S. Konduri, Sandhya D. Nandedkar, S. Deenamsetty, D. A. Rickaby, and Nejat Düzgüneş
Cancer cell-specific luciferase expression driven by the human survivin promoter, Krystyna Konopka, Nathan Overlid, F. Li, and Nejat Düzgüneş
Serum decreases the size of metafectene- and GeneJammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells, Krystyna Konopka, Nathan Overlid, Anitha C. Nagaraj, and Nejat Düzgüneş
