A selection of published journal articles from faculty members of the Arthur A. Dugoni School of Dentistry at University of the Pacific.

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Submissions from 1998

Apoptosis of epithelial cells and macrophages due to infection with the obligate intracellular pathogen Chlamydia psittaci, David M. Ojcius, Philippe Souque, Jean-Luc Perfettini, and Alice Dautry-Varsat

[Endodontists--specialists in saving teeth. The AAE annual congress of 7 to 11 May 19977 in Seattle. American Association of Endodontists]., Ove A. Peters and C. Eggert

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Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides, Sérgio Simões, Vladimir Slepushkin, R. Caspar, Maria C. Pedroso de Lima, and Nejat Düzgüneş

Submissions from 1997

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Determinant selection for T-cell tolerance in HEL-transgenic mice: dissociation between immunogenicity and tolerogenicity, Laurent Gapin, Jean-Pierre Cabaniols, Ricardo Cibotti, David M. Ojcius, Philippe Kourilsky, and Jean M. Kanellopoulos

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Heparin-mediated inhibition of Chlamydia psittaci adherence to HeLa cells, Cesar Gutiérrez-Martín, David M. Ojcius, Ru-Ching Hsia, Raymond Hellio, Patrik M. Bavoil, and Alice Dautry-Varsat

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Cationic liposome-mediated expression of HIV-regulated luciferase and diphtheria toxin a genes in HeLa cells infected with or expressing HIV, Krystyna Konopka, Gail S. Harrison, Philip L. Felgner, and Nejat Düzgüneş

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Birt-Hogg-Dubé syndrome: A review and presentation of the first case with oral lesions, Nader A. Nadershahi, William B. Wescott, and Barbara Egbert

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Distribution of endosomal, lysosomal and MHC markers in a monocytic cell line infected with Chlamydia psittaci, David M. Ojcius, Raymond Hellio, and Alice Dautry-Varsat

Aufbereitung gekrümmter Wurzelkanäle mit der Lightspeed-Methode, Ove A. Peters, C. Eggert, and Fred Barbakow

Wurzelkanaloberflächen nach Lightspeed-Präparation im REM dargestellt-eine Pilotstudie, Ove A. Peters, C. Eggert, and Fred Barbakow

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Inhibition of human immunodeficiency virus type-1 replication in macrophages and H9 cells by free or liposome-encapsulated L-689,502, an inhibitor of the viral protease, Elizabeth Pretzer, Diana L. Flasher, and Nejat Düzgüneş

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The anti-HIV-1 activity associated with saliva, Nancy R. Shine, Krystyna Konopka, and Nejat Düzgüneş

Effect of recombinant secretory leukocyte protease inhibitor on hiv infection in human macrophages, Nancy R. Shine, Krystyna Konppka, and Nejat Düzgüneş

Enhancement of cationic liposome-mediated gene delivery by transferrin and fusogenic peptides, Sérgio Simoes, Vladimir Slepushkin, R. Gaspar, Maria C. Pedroso de Lima, and Nejat Düzgüneş

Transfection of human blood monocyte-derived macrophages by transferrin-cationic lipid-DNA complexes, Sérgio Simões, Vladimir Slepushkin, Elizabeth Pretzert, Rogério Gaspar, Maria C. Pedroso De Lima, and Nejat Düzgüneş

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Sterically stabilized pH-sensitive liposomes. Intracellular delivery of aqueous contents and prolonged circulation in vivo, Vladimir A. Slepushkin, Sérgio Simões, Paul Dazin, Mary S. Newman, Luke S. Guo, Maria C. Pedroso De Lima, and Nejat Düzgüneş

Submissions from 1996

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Dynorphin-phospholipid membrane interactions: Role of phospholipid head-group and cholesterol, Dennis R. Alford, V. Renugopalakrishnan, and Nejat Düzgüneş

Cell suicide in health and disease, Richard C. Duke, David M. Ojcius, and John Ding-E. Young

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Treatment of intracellular Mycobacterium avium complex infection by free and liposome-encapsulated sparfloxacin, Nejat Düzgüneş, Diana L. Flasher, M. Venkata Reddy, Julieta Luna-Herrera, and Pattisapu R.J. Gangadharam

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Introduction: novel specific immunity functioning alongside classical specific immunity, G. Gachelin, I. Apostolou, and David M. Ojcius

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Human immunodeficiency virus type-1 (HIV-1) infection increases the sensitivity of macrophages and THP-1 cells to cytotoxicity by cationic liposomes, Krystyna Konopka, Elizabeth Pretzer, Philip L. Felgner, and Nejat Düzgüneş

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Presentation of antigens derived from microorganisms residing in host-cell vacuoles, David M. Ojcius, Gabriel Gachelin, and Alice Dautry-Varsat

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Immunology and the confocal microscope, David M. Ojcius, F. Niedergang, A. Subtil, Raymond Hellio, and Alice Dautry-Varsat

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Targeting of liposomes to HIV-1-infected cells by peptides derived from the CD4 receptor, Vladimir A. Slepushkin, Isam Ismail Salem, Sergei M. Andreev, Paul Dazin, and Nejat Düzgüneş

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High incidence of Coxiella burnetii markers in a rural population in France, Monique Thibon, Veronique Villiers, Philippe Souque, Alice Dautry-Varsat, Regis Duquesnel, and David M. Ojcius

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Interleukin-10 inhibits tumor metastasis through an NK-cell dependent mechanism, Li-Mou Zheng, David M. Ojcius, F. Garaud, C. Roth, E. Maxwell, Z. Li, H. Rong, J. Chen, X. Y. Wang, J. J. Catino, and I. King

Submissions from 1995

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Liposome-mediated therapy of human immunodeficiency virus type-1 and mycobacterium infections, Nejat Düzgüneş, Diana L. Flasher, Elizabeth Pretzer, Krystyna Konopka, Vladimir A. Slepushkin, Gerhard Steffan, Isam I. Salem, M. Venkata Reddy, and Pattisapu R.J. Gangadharam

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Therapy of Mycobacterium avium complex infections in beige mice with streptomycin encapsulated in sterically stabilized liposomes, Pattisapu R.J. Gangadharam, D. R. Ashtekar, Diana L. Flasher, and Nejat Düzgüneş

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A monoclonal antibody to the gp120-CD4 complex has differential effects on HIV-induced syncytium formation and viral infectivity, Krystyna Konopka, Elizabeth Pretzer, F. Celada, and Nejat Düzgüneş

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Differential effects of a hydrophobic tripeptide on human immunodeficiency virus type 1 (HIV-1)-induced syncytium formation and viral infectivity, Krystyna Konopka, Elizabeth Pretzer, and Nejat Düzgüneş

Les mille et une ruses des microbes intracellulaires, David M. Ojcius and Alice Dautry-Varsat

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pH and calcium dependence of hemolysis due to Rickettsia prowazekii: comparison with phospholipase activity, David M. Ojcius, M. Thibon, C. Mounier, and Alice Dautry-Varsat

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Target cell membrane sialic acid modulates both binding and fusion activity of influenza virus, Maria C. Pedroso de Lima, João Ramalho-Santos, Diana L. Flasher, Vladimir A. Slepushkin, Shlomo Nir, and Nejat Düzgüneş

Submissions from 1994

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Picosecond fluorescence spectroscopy of a single-chain class I major histocompatibility complex-encoded protein in its peptide loaded and unloaded states, Kerstin Dittes, D. Gakamsky, Elisha Haas, David M. Ojcius, Philippe Kourilsky, Israel Pecht, and Gilad Haran

Cytolysis mediated by ionophores and pore-forming agents: role of intracellular calcium in apoptosis, Richard C. Duke, R. Z. Witter, P. B. Nash, John Ding-E. Young, and David M. Ojcius

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Liposome targeting to human immunodeficiency virus type 1-infected cells via recombinant soluble CD4 and CD4 immunoadhesin (CD4-IgG), Diana Flasher, Krystyna Konopka, Steven M. Chamow, Paul Dazin, Avi Ashkenazi, Elizabeth Pretzer, and Nejat Düzgüneş

Reflex patterns in postganglionic neurons supplying skin and skeletal muscle of the rat hindlimb., H. J. Häbler, W. Jänig, M. Krummel, and Ove A. Peters

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Role of the CDR1 of the TCR β chain in the binding to a MHC-peptide complex, Yu-Chun Lone, Maria Bellio, Ada Prochnicka-Chalufour, David M. Ojcius, Nicolas Boissel, Tom H. M. Ottenhoff, Richard D. Klausner, Jean-Pierre Abastado, and Philippe Kourilsky

Major contribution of the Vb chain to the antigen specificity of a TCR, Yu-Chun Lone, David M. Ojcius, M. Bellio, Philippe Kourilsky, and J.-P. Abastado

Monosynaptic excitation of preganglionic vasomotor neurons by subretrofacial neurons of the rostral ventrolateral medulla., R. M. McAllen, H. J. Häbler, M. Michaelis, Ove A. Peters, and W. Jänig

Major histocompatibility complex class I molecules and resistance to infection by intracellular pathogens, David M. Ojcius, Christiane Delarbre, Philippe Kourilsky, and Gabriel Gachelin

Is antigen processing guided by major histocompatibility complex molecules?, David M. Ojcius, L. Gapin, Jean M. Kanellopoulos, and Philippe Kourilsky

Role for MHC class I molecules in selecting and protecting high affinity peptides in the presence of proteases, David M. Ojcius, P. Langlade-Demoyen, Gabriel Gachelin, and Philippe Kourilsky

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Ly-49-independent inhibition of NK cell-mediated cytotoxicity by a soluble MHC class I molecule, Claude Roth, Philippe Kourilsky, and David M. Ojcius

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Separate metabolic pathways leading to DNA fragmentation and apoptotic nuclear chromatin condensation, D. Sun, Shibo Jiang, Li-Mou Zheng, David M. Ojcius, and John Ding-E. Young

Submissions from 1993

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A soluble, single-chain Kd molecule produced by yeast selects a peptide repertoire indistinguishable from that of cell-surface-associated Kd, Jean-Pierre Abastado, David M. Ojcius, Amanda Casrouge, Patrice Yeh, Ton N. M. Schumacher, Hidde L. Ploegh, and Philippe Kourilsky

Respiratory modulation of the activity in postganglionic neurons supplying skeletal muscle and skin of the rat hindlimb., H. J. Häbler, W. Jänig, M. Krummel, and Ove A. Peters

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Anionic liposomes inhibit human immunodeficiency virus type 1 (HIV-1) infectivity in CD4+ A3.01 and H9 cells, Krystyna Konopka, B. R. Davis, C. E. Larsen, and Nejat Düzgüneş

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Long-Term Noncytopathic Productive Infection of the Human Monocytic Leukemia Cell Line THP-1 by Human Immunedeficiency Virus Type 1 (HIV-1IIIB), Krystyna Konopka, Elizabeth Pretzer, Barbara Plowman, and Nejat Düzgüneş

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Human immunodeficiency virus type 1 (HIV-1) fusion with model membranes: kinetic analysis and the role of lipid composition, pH and divalent cations, Charles E. Larsen, Shlomo Nir, Dennis R. Alford, Myra Jennings, Kyung Dall Lee, and Nejat Düzgüneş

Dissociation of the peptide-MHC class I complex limits the binding rate of exogenous peptide, David M. Ojcius, Jean-Pierre Abastado, Amanda Casrouge, E. Mottez, L. Cabanie, and Philippe Kourilsky

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Binding of alanine-substituted peptides to the MHC class I protein Kd, David M. Ojcius, Jean-Pierre Abastado, F. Godeau, and Philippe Kourilsky

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Dissociation of the peptide/MHC class I complex: pH dependence and effect of endogenous peptides on the activation energy, David M. Ojcius, L. Gapin, and Philippe Kourilsky

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Real-time measurement of antigenic peptide binding to empty and preloaded single-chain MHC class I molecules, David M. Ojcius, Francois Godeau, Jean-Pierre Abastado, Jean-Laurent Casanova, and Philippe Kourilsky

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A Common Mechanism for Influenza Virus Fusion Activity and Inactivation, João Ramalho-Santos, Shlomo Nir, Nejat Düzgüneş, Arsélio Pato de Carvalho, and Maria Conceição Pedroso De Lima

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Simian immunodeficiency virus (SIV(mac)251) membrane lipid mixing with human CD4+ and CD4- cell lines in vitro does not necessarily result in internalization of the viral core proteins and productive infection, L. Stamatatos and Nejat Düzgüneş

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Distribution of perforin-containing cells in normal and pregnant mice, Li-Mou Zheng, David M. Ojcius, and John Ding-E. Young

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Perforin-containing cells during spontaneous abortion, Li-Mou Zheng, David M. Ojcius, and John Ding-E. Young

Submissions from 1992

Targeted drug delivery., Nejat Düzgüneş

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Fusion activity and inactivation of influenza virus: Kinetics of low pH-induced fusion with cultured cells, Nejat Düzgüneş, Maria C. Pedroso de Lima, L. Stamatatos, D. Flasher, D. R. Alford, Daniel S. Friend, and S. Nir

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Membrane destabilization by N-terminal peptides of viral envelope proteins, Nejat Düzgüneş and Sergei A. Shavnin

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Purification and ligand binding of a soluble class I MHC molecule consisting of the first three domains of H-2Kd fused to b2-microglobulin expressed in the baculovirus/insect cell system, Francois Godeau, Immanuel F. Luescher, David M. Ojcius, Cecile Saucier, Estelle Mottez, Lucien Cabanie, and Philippe Kourilsky

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Efficacies of liposome-encapsulated streptomycin and ciprofloxacin against Mycobacterium avium-M. intracellulare complex infections in human peripheral blood monocyte/macrophages, S. Majumdar, Diana L. Flasher, Daniel S. Friend, P. Nassos, D. Yajko, W. K. Hadley, and Nejat Düzgüneş

Peptide binding to MHC class I proteins measured with a novel fluorescent technique, David M. Ojcius, Jean-Pierre Abastado, F. Godeau, and Philippe Kourilsky

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Channel forming activity of the perforin N-terminus and an a-helical region homologous with complement C9, P. M. Persechini, David M. Ojcius, S. C. Adeodato, Paulo C. Notaroberto, C. B. Daniel, and John Ding-E. Young

Submissions from 1991

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Activity of free and liposome encapsulated streptomycin against mycobacterium avium complex (MAC) inside peritoneal macrophages, D. Ashtekar, Nejat Düzgüneş, and P. R.J. Gangadharam

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Phospholipid studies of marine organisms: 26. Interactions of some marine sterols with 1-stearoyl-2-oleoyl phosphatidylcholine (SOPC) in model membranes, Meilleko C. Dai, Huong Bich Chiche, Nejat Düzgüneş, Eser Ayanoglu, and Carl Djerassi

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Chemotherapeutic potential of free and liposome encapsulated streptomycin against experimental mycobacterium avium complex infections in beige mice, Pattisapu R.J. Gangadharam, Dilip A. Ashtekar, Naheed Ghori, Jayne A. Goldstein, Robert J. Debs, and Nejat Düzgüneş

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Cell death mechanisms and the immune system, Pierre Golstein, David M. Ojcius, and John Ding-E. Young

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Enhancement of human immunodeficiency virus type 1 infection by cationic liposomes: The role of CD4, serum and liposome-cell interactions, Krystyna Konopka, L. L. Stamatatos, C. E. Larsen, B. R. Davis, and Nejat Düzgüneş

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Cytoplasts from cytotoxic T lymphocytes are resistant to perforin-mediated lysis, David M. Ojcius, Shibo Jiang, Pedro M. Persechini, Patricia A. Detmers, and John Ding-E. Young

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Plasma membrane-associated proteins with the ability to partially inhibit perforin-mediated lysis, David M. Ojcius, Sylviane Muller, Cynthia S. Hasselkus-Light, John Ding-E. Young, and Shibo Jiang

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Cytolytic and ion channel forming properties of the N-terminus of lymphocyte perforin, David M. Ojcius, Pedro M. Persechini, Li-Mou Zheng, Paulo C. Notaroberto, Sandro C. Adeodato, and John Ding-E. Young

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Cytolytic peptides and proteins: Is there a common structural motif?, David M. Ojcius and John Ding-E. Young

Subcellular localization of perforin and serine esterase in lymphokine-activated killer (LAK) cells and cytotoxic T cells by immunogold labelling, David M. Ojcius, L. M. Zheng, E. C. Sphicas, A. Zychilinsky, and John Ding-E. Young

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Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes, David M. Ojcius, Arturo Zychlinsky, Li-Mou Zheng, and John Ding-E. Young

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Fusion of Sendai virus with human HL-60 and CEM cells: different kinetics of fusion for two isolates, Maria C. Pedroso de Lima, Shlomo Nir, Diana L. Flasher, Karin Klappe, Dick Hoekstra, and Nejat Düzgüneş

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Expression of lymphocyte perforin in the mouse uterus during pregnancy, Li-Mou Zheng, Chau-Ching Liu, David M. Ojcius, and John Ding-E. Young

Immunogold labelling of perforin and serine esterases in granulated metrial gland cells, Li-Mou Zheng, David M. Ojcius, Chau-Ching Liu, M. D. Kramer, M. M. Simon, E. L. Parr, and John Ding-E. Young

Role of granulated metrial gland cells in the immunology of pregnancy, Li-Mou Zheng, David M. Ojcius, and John Ding-E. Young

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Extracellular ATP as a trigger for apoptosis or programmed cell death, Li-Mou Zheng, Arturo Zychlinsky, Chau-Ching Liu, David M. Ojcius, and John Ding-E. Young

Submissions from 1990

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Isolation and characterization of the gene encoding the muscle-specific isozyme of human phosphoglycerate mutase

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Cholesterol Interactions with Tetracosenoic Acid Phospholipids in Model Cell Membranes: Role of the Double-Bond Position, Eser Ayanoglu, Bich Huong Chiche, Mark Beatty, Carl Djerassi, and Nejat Düzgüneş

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In situ mapping of the muscle-specific form of phosphoglycerate mutase gene to human chromosome 7p12-7p13, Judit Castella-Escola, M. G. Mattei, David M. Ojcius, E. Passage, C. Valentin, and M. Cohen-Solal

Regulation of gene expression in vivo by liposome-mediated delivery of a purified transcription factor, Robert J. Debs, L. P. Freedman, S. Edmunds, K. L. Gaensler, Nejat Düzgüneş, and K. R. Yamamoto

Immunomodulatory and Toxic Effects of Free and Liposome-encapsulated Tumor Necrosis Factor a in Rats1, Robert J. Debs, Henry J. Fuchs, Ramila Philip, Elisa N. Brunette, Nejat Düzgüneş, Judd E. Shellito, Denny Liggitt, and John R. Patton

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Monocyte-Mediated Lysis of HIV-Infected Tumor Cells, Robert J. Debs, John Krowka, Daniel Stites, Elisa N. Brunette, Nejat Düzgüneş, and Ramila Philip

Molecular control of vesicle aggregation and membrane fusion: Hypotheses on bile vesicles, Nejat Düzgüneş

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Purification of a membrane-associated serine esterase from murine cytotoxic T lymphocytes by a single reverse phase column, Shibo Jiang, Cynthia S. Hasselkus-Light, David M. Ojcius, and John Ding-E. Young

Resistance of cytolytic lymphocytes to perforin-mediated killing: Inhibition of perforin binding activity by surface membrane proteins, Shibo Jiang, David M. Ojcius, Pedro M. Persechini, and John Ding-E. Young

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Perforin binding to cells and lipid membranes determined by a simple competition assay, Shibo Jiang, David M. Ojcius, and John Ding-E. Young

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Differential effects of free and liposome encapsulated amikacin on the survival of Mycobacterium avium complex in mouse peritoneal macrophages, L. Kesavalu, Jayne A. Goldstein, Robert J. Debs, Nejat Düzgüneş, and Pattisapu R.J. Gangadharam

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Liposomes modulate human immunodeficiency virus infectivity, Krystyna Konopka, B. R. Davis, C. E. Larsen, D. R. Alford, Robert J. Debs, and Nejat Düzgüneş

Lymphocyte proliferative responses to soluble and liposome-conjugated envelope peptides of HIV-1, J. Krowka, D. Stites, Robert J. Debs, C. Larsen, Jane Fedor, E. Brunette, and Nejat Düzgüneş

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Fusion of simian immunodeficiency virus with liposomes and erythrocyte ghost membranes: Effects of lipid composition, pH and calcium, Charles E. Larsen, D. R. Alford, L. J.T. Young, T. P. McGraw, and Nejat Düzgüneş

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Fusion of enveloped viruses with cells and liposomes - Activity and inactivation, Shlomo Nir, Nejat Düzgüneş, Maria C. Pedroso De Lima, and Dick Hoekstra

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Resistance to the pore forming protein of cytotoxic T cells: comparison of target cell membrane rigidity, David M. Ojcius, Shibo Jiang, Pedro M. Persechini, Judith Storch, and John Ding-E. Young

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Restriction factors of homologous complement: A new candidate?, David M. Ojcius, Shibo Jiang, and John Ding-E. Young

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A role for pore-forming proteins in the pathogenesis by parasites?, David M. Ojcius and John Ding-E. Young

Cell-mediated killing: effector mechanisms and mediators, David M. Ojcius and John Ding-E. Young