A selection of published journal articles from faculty members of the Arthur A. Dugoni School of Dentistry at University of the Pacific.

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Submissions from 2009

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Expression and characterization of recombinant human secretory leukocyte protease inhibitor (SLPI) protein from Pichia pastoris, Zhiguo Li, Allison Moy, Kirti Sohal, Carolyn Dam, Peter Kuo, James Whittaker, Mei Whittaker, Nejat Düzgünes, Krystyna Konopka, Andreas H. Franz, Joan Lin-Cereghino, and Geoff P. Lin-Cereghino

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Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity, Dongjiao Luo, Feng Xue, David M. Ojcius, Jinfang Zhao, Ya-Fei Mao, Liwei Li, Xu'ai Lin, and Jie Yan

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Life balance and the busy dental professional, Lucinda J. Lyon and Nader A. Nadershahi

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An iterative strategy combining biophysical criteria and duration hidden Markov) models for structural predictions of Chlamydia trachomatis s66 promoters, Ronna R. Mallios, David M. Ojcius, and David H. Ardell

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Building a fulfilling life by managing the various stages of your career, Nader A. Nadershahi

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Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response, S. Neves, Henrique Faneca, S. Bertin, Krystyna Konopka, Nejat Düzgüneş, V. Pierrefite-Carle, S. Simões, and M. C. Pedroso De Lima

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Chikungunya fever: re-emergence of an old disease, Lisa F. P. Ng and David M. Ojcius

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Effects of root canal preparation on apical geometry assessed by micro-computed tomography., Frank Paqué, Daniel Ganahl, and Ove A. Peters

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The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope, Jean-Luc Perfettini, Roberta Nardacci, C. Séror, M. Bourouba, F. Subra, L. Gros, Gwenola Manic, A. Amendola, P. Masdehors, F. Rosselli, David M. Ojcius, C. Auclair, H. de Thé, M. L. Gougeon, M. Piacentini, and G. Kroemer

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The danger signal adenosine induces persistence of chlamydial infection through stimulation of A2b receptors, Matthew A. Pettengill, Verissa W. Lam, and David M. Ojcius

Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNg in human epithelial cells, L. Welter-Stahl, C. M. da Silva, Julieta Schachter, Pedro M. Persechini, H. S. Souza, David M. Ojcius, and Robson Coutinho-Silva

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PICK1 deficiency causes male infertility in mice by disrupting acrosome formation, Nan (Tori) Xiao, Chuen Kam, Chong Shen, Wenying Jin, Junqi Wang, Kwong Man Lee, Liwen Jiang, and Jun Xia

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Use of the masseteric and deep temporal nerve blocks for the reduction of mandibular dislocation, Andrew L. Young, Junad Khan, Davis C. Thomas, and Samuel Y. P. Quek

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Inhibition of Vascular Endothelial Growth Factor Receptor-1/Wnt/{beta}-catenin Crosstalk Leads to Tumor Cell Death, Benjamin David Zeitlin, Lee M. Ellis, and Jacques E. Nör

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Temperature changes during ultrasonic irrigation with different inserts and modes of activation., Marco Zeltner, Ove A. Peters, and Frank Paqué

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Comparison of the effects of crocetin and crocin on myocardial injury in rats, Rong Zhang, Zhi Yu Qian, Xiaoyuan Han, Zhen Chen, Jun Ling Yan, and A. Hamid

Submissions from 2008

Susceptibility of Chlamydia trachomatis to the excipient hydroxy-ethylcellulose: pH and concentration dependence of antimicrobial activity, Ali A. Abdul-Sater, David M. Ojcius, and M. P. Meyer

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The association between gingival crevicular fluid TGF-β1 levels and periodontal status in HIV-1+ patients, Tamer Alpagot, Krystyna Konopka, Mouchumi Bhattacharyya, S. Gebremedhin, and Nejat Düzgüneş

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The book reopened on infectious diseases, Maria Avila, Najwane Said, and David M. Ojcius

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Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein, Haiyan Dong, Ye Hu, Feng Xue, Dexter Sun, David M. Ojcius, Yafei Mao, and Jie Yan

Sitimagene ceradenovec, a gene therapeutic for the treatment of glioma, Nejat Düzgüneş

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Bite force and pattern measurements for dental pain assessment in the rat, Junad Khan, Rafael Benoliel, Uri Herzberg, Andrew J. Mannes, Robert M. Caudle, Andrew L. Young, and Eli Eliav

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Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease, Stefan A. Paschen, Jan G. Christian, Juliane Vier, Franziska Schmidt, Axel Walch, David M. Ojcius, and Georg Hacker

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Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia, Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frederic Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M. Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, Jose R. Regueiro, Hughes de Thé, Marie-Lise Gougeon, Mauro Piacentini, and Guido Kroemer

Accessing root canal systems: knowledge base and clinical techniques, Ove A. Peters

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Recombinant SpaO and H1a as immunogens for protection of mice from lethal infection with Salmonella paratyphi A: implications for rational design of typhoid fever vaccines, Ping Ruan, Xiao-Ping Xia, Dexter Sun, David M. Ojcius, Ya-Fei Yao, Wen-Yue Yue, and Jie Yan

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Enzastaurin, an inhibitor of PKC beta, Enhances Antiangiogenic Effects and Cytotoxicity of Radiation against Endothelial Cells., Aaron C. Spalding, Benjamin David Zeitlin, Kari Wilder-Romans, Mary Ellen Davis, Jacques E. Nör, Theodore S. Lawrence, and Edgar Ben-Josef

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ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X(7)-mediated host-cell apoptosis, Özlem Yilmaz, L. Yao, K. Maeda, T. M. Rose, E. L. Lewis, M. Duman, R. J. Lamont, and David M. Ojcius

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Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development, Songmin Ying, Matthew A. Pettengill, E. Ray Latham, Axel Walch, David M. Ojcius, and Georg Hacker

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A novel approach in assessment of coronal leakage of intraorifice barriers: a saliva leakage and micro-computed tomographic evaluation., Parisa Zakizadeh, Sally J. Marshall, Charles I. Hoover, Ove A. Peters, W. Craig Noblett, Stuart A. Gansky, and Harold E. Goodis

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Expanding circle of inhibition: small-molecule inhibitors of Bcl-2 asanticancer cell and antiangiogenic agents, Benjamin David Zeitlin, Isaac J. Zeitlin, and Jacques E. Nör

Submissions from 2007

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Longitudinal evaluation of prostaglandin E2 (PGE2) and periodontal status in HIV+ patients, Tamer Alpagot, John Remien, Mouchumi Bhattacharyya, Krystyna Konopka, William Lundergan, and Nejat Düzgüneş

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Impact of lubricant parameters on rotary instrument torque and force., Claudia Boessler, Ove A. Peters, and Matthias Zehnder

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The origins of fear of occupational exposure in the clinical dental setting, David W. Chambers, Nader A. Nadershahi, and Howard Chi

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The role of P2 receptors in controlling infections by intracellular pathogens, Robson Coutinho-Silva, Christiane Monteiro da Cruz, Pedro M. Persechini, and David M. Ojcius

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ATP activates a Reactive Oxygen Species-dependent oxidative stress response and secretion of pro-inflammatory cytokines in macrophages, Christiane M. Cruz, Alessandra Rinna, Henry Jay Forman, Ana L. M. Ventura, Pedro M. Persechini, and David M. Ojcius

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Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally-infected mice, Toni Darville, Lynn Welter-Stahl, Christiane Cruz, Ali Abdul-Sater, Charles W. Andrews Jr., and David M. Ojcius

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Level of endothelial cell apoptosis required for a significant decrease in microvessel density, Zhihong Dong, Benjamin David Zeitlin, Wenying Y. Song, Qinghua H. Sun, Elisabeta Karl, David M. Spencer, Harsh Vardhan Jain, Trachette L. Jackson, Gabriel Nunez, and Jacques E. Nör

A new paradigm for NIH grants, Nejat Düzgüneş

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Serum-resistant lipopolyplexes for gene delivery to liver tumour cells, Leire García, Maria Buñuales, Nejat Düzgüneş, and Conchita Tros de Ilarduya

Integration and Reform of International and Pre-doctoral Dental Curricula, Lisa E. Itaya and Nader A. Nadershahi

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Bcl-2 orchestrates a cross-talk between endothelial and tumor cells that promotes tumor growth, Tomoatsu Kaneko, Zhaocheng Zhang, Maria G. Mantellini, Mark W. Lingen, Robert M. Strieter, Gabriel Nunez, and Jacques E. Nör

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Comparison of invasion of fibroblasts and macrophages by high- and low-virulence Leptospira strains: colonization of the host-cell nucleus and induction of necrosis by the virulent strain, L. Li, David M. Ojcius, and J. Yan

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Expression of recombinant proteins in Pichia pastoris, Pingzuo Li, Anukanth Anumanthan, Xiu Gong Gao, Kuppusamy Ilangovan, Vincent V. Suzara, Nejat Düzgüneş, and V. Renugopalakrishnan

Call for New Leaders: Variety of opportunities available in 2008, Nader A. Nadershahi and C. Brattesani

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The Th1 immune response against HIV-1 Gag p24-derived peptides in mice expressing HLA-A02.01 and HLA-DR1, Anthony Pajot, Aurelie Schnuriger, Arnaud Moris, Audrey Rodallec, David M. Ojcius, Brigitte Austran, Francois A. Lemonnier, and Yu-Chun Lone

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Effect of immersion in sodium hypochlorite on torque and fatigue resistance of nickel-titanium instruments., Ove A. Peters, Jan O. Roehlike, and Michael A. Baumann

Taktile Erfassung von artifiziellen Wurzelkanalgeometrien durch Studierende, David Sonntag, K. Kook, B. Mann, Ove A. Peters, and V. Stachniss

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Effect of prion decontamination protocols on nickel-titanium rotary surfaces., David Sonntag and Ove A. Peters

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Correlation between infections with different genotypes of human cytomegalovirus and Epstein-Barr virus in subgingival samples and the periodontal status of patients, Yan-Min Wu, Jie Yan, David M. Ojcius, Li-Li Chen, Zhi-Yuan Gu, and Jian-Peng Pan

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Host-cell survival and death during Chlamydia infection, Songmin Ying, Matthew A. Pettengill, David M. Ojcius, and Georg Hacker

Submissions from 2006

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Anti-tumour activity in non-small cell lung cancer models and toxicity profiles for novel ruthenium(II) based organo-metallic compounds, Sylvie M. Guichard, Roderick W. Else, Benjamin David Zeitlin, Morwenna Muir, Michael Dodds, Heinz-Herbert Fiebig, Peter J. Sadler, and Duncan I. Jodrell

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Serum decreases the size of metafectene- and GeneJammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells, Krystyna Konopka, Nathan Overlid, Anitha C. Nagaraj, and Nejat Düzgüneş

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Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X(7)-associated pore or channel formation, Christiane M. Monteiro da Cruz, Ana Lucia Marques Ventura, Julieta Schachter, Helio Miranda Costa-Junior, Hercules Antonio da Silva Souza, Fernanda Ramos Gomes, Robson Coutinho-Silva, David M. Ojcius, and Pedro M. Persechini

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Identification of novel HLA-DR1-restricted epitopes from the hepatitis B virus envelope protein in mice expressing HLA-DR1 and vaccinated human subjects, Anthony Pajot, Marie-Louise Michel, Maryline Mancini-Bourgine, Marie-Noelle Ungeheuer, David M. Ojcius, Qiang Deng, Francois A. Lemonnier, and Yu-Chun Lone

Accessing root canal systems: requirements and techniques., Ove A. Peters

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Activation of iCaspase-9 in neovessels inhibits oral tumor progression, Matthew Stephen Pinsky, Wenying Song, Zhihong Dong, Kristy Warner, Benjamin David Zeitlin, Elisabeta Karl, Daniel E. Hall, and Jacques E. Nör

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Antitumoral activity of transferrin-lipoplexes carrying the IL-12 gene in the treatment of colon cancer, Conchita Tros De Ilarduya, Maria Buñuales, Cheng Qian, and Nejat Düzgüneş

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Soft tissue management: flap design, incision, tissue elevation and tissue retraction, Peter Velvert, Christine I. Peters, and Ove A. Peters

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Soft tissue management: suturing and wound closure, Peter Velvert, Christine I. Peters, and Ove A. Peters

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Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival, Philippe Verbeke, Lynn Welter-Stahl, S. Ying, J. Hansen, Georg Hacker, Toni Darville, and David M. Ojcius

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Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum, L. Welter-Stahl, David M. Ojcius, J. Viala, S. Girardin, W. Liu, C. Delarbre, D. Philpott, K. A. Kelley, and T. Darville

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Student occupational exposure incidence: perception versus reality, A. Jeffrey Wood, Nader A. Nadershahi, Richard E. Fredekind, Eve J. Cuny, and David W. Chambers

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In vitro investigation on force degradation of elastomeric chains, Nan (Tori) Xiao and Ding Zhang

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Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells, Özlem Yilmaz, Philippe Verbeke, Richard J. Lamont, and David M. Ojcius

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Characterization of host cell death induced by Chlamydia trachomatis, Songmin Ying, Silke F. Fischer, Matthew A. Pettengill, Debye Conte, Stefan A. Paschen, David M. Ojcius, and Georg Hacker

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Antiangiogenic effect of TW37, a small-molecule inhibitor of Bcl-2, Benjamin David Zeitlin, Esther Joo, Zhihong Dong, Kristy Warner, Guo-Liang Wang, Zaneta Nikolovska-Coleska, Shaomeng Wang, and Jacques E. Nör

Submissions from 2005

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A role for mitogen-activated protein kinase (Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death, Rodolphe Auger, Iris Motta, Karim Benihoud, David M. Ojcius, and Jean M. Kanellopoulos

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Association between coinfection of Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Treponema denticola and periodontal tissue destruction in chronic periodontitis, L. L. Chen, Y. M. Wu, J. Yan, W. L. Sun, Y. Z. Sun, and David M. Ojcius

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Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages, Robson Coutinho-Silva, David M. Ojcius, D. C. Górecki, Pedro M. Persechini, R. C. Bisaggio, A. N. Mendes, J. Marks, G. Burnstock, and P. M. Dunn

P2X and P2Y purinergic receptors on human intestinal epithelial carcinoma cells: effects of extracellular nucleotides on apoptosis and cell proliferation, Robson Coutinho-Silva, Lynn Stahl, K. K. Cheung, N. E. de Campus, C. de Oliveira Souza, David M. Ojcius, and G. Burnstock

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Mechanical preparation of root canals: shaping goals, techniques and means, Michael Hülsmann, Ove A. Peters, and Paul H. M. Dummer

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Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines, Elisabeta Karl, Kristy Anne Warner, Benjamin David Zeitlin, Tomoatsu Kaneko, Lindsey Elizabeth Wurtzel, Taocong Jin, Jia Chang, Shaomeng Wang, Cun-Yu Wang, Robert M. Strieter, Gabriel Nunez, and Jacques E. Nör

Serum-resistant gene transfer to oral cancer cells by Metafectene and GeneJammer: Application to HSV-tk/ganciclovir-mediated cytotoxicity, Krystyna Konopka, Basma Fallah, Jomarie Monzon-Duller, Nathan Overlid, and Nejat Düzgüneş

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Factors affecting the outcome of orthograde root canal therapy in a general dentistry hospital practice., Monika Marending, Ove A. Peters, and Matthias Zehnder

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Educating the practice-ready dentist, Nader A. Nadershahi and David B. Nielsen

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Chlamydia trachomatis induces expression of IFN-g-inducible protein 10 and IFN-b independent of TLR2 and TLR4, but largely dependent on MyD88, Uma M. Nagarajan, David M. Ojcius, Lynn Stahl, Roger G. Rank, and Toni Darville

Can chlamydia be stopped?, David M. Ojcius, Toni Darville, and Patrik M. Bavoil

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Root canal preparation with Endo-Eze AET: changes in root canal shape assessed by micro-computed tomography., Frank Paqué, Fred Barbakow, and Ove A. Peters

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Calcium hydroxide dressings using different preparation and application modes: density and dissolution by simulated tissue pressure., Christine I. Peters, R. S. Koka, S. Highsmith, and Ove A. Peters

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Effect of liquid and paste-type lubricants on torque values during simulated rotary root canal instrumentation., Ove A. Peters, Claudia Boessler, and Matthias Zehnder

Analysis of torque and force with differently tapered rotary endodontic instruments in vitro., Charlotte Schrader and Ove A. Peters

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Cationic liposomes for gene delivery, Sérgio Simões, Ana Filipe, Henrique Faneca, Miguel Mano, Nuno Penacho, Nejat Düzgüneş, and Maria C. Pedroso De Lima

Effect of cyclic fatigue on static fracture loads in ProTaper nickel-titanium rotary instruments., Cheryl J. Ullmann and Ove A. Peters

Gene therapy for oral cancer: efficient delivery of a 'suicide gene' to murine oral cancer cells in physiological milieu., Mark Young, Nathan Overlid, Krystyna Konopka, and Nejat Düzgüneş

Submissions from 2004

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Risk factors for periodontitis in HIV+ patients, Tamer Alpagot, Nejat Düzgüneş, Larry F. Wolff, and Aaaron Lee

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Chlamydia, Robert Belland, David M. Ojcius, and Gerald I. Byrne

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Chlamydia and apoptosis: life and death decisions of an intracellular pathogen, Gerald I. Byrne and David M. Ojcius

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Isolation and characterization of Psalmopeotoxin I and II: two novel antimalarial peptides from the venom of the tarantula Psalmopoeus cambridgei, Soo-Jin Choi, Romain Parent, Carole Guillaume, Christiane Deregnaucourt, Christiane Delarbre, David M. Ojcius, Jean-Jacques Montagne, Marie-Louise L. Celerier, Aude Phelipot, Mohamed Amiche, Jordi Molgo, Jean-Michel Camadro, and Catherine Guette

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Protection against Chlamydia trachomatis infection in vitro and modulation of inflammatory response in vivo by membrane-associated glycosaminoglycans, Toni Darville, Saul Yedgar, M. Krimsky, C. W. Andrews Jr., Thomas Jungas, and David M. Ojcius

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Perceptions of dental schools from within and outside the university, Douglas N. Dederich, Patrick M. Lloyd, Cherae Dixon-Farmer, Kathy Voight Geurink, Nader A. Nadershahi, Fonda G. Robinson, and Frank A. Scannapieco

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Cell death, BAX activation, and HMGB1 release during infection with Chlamydia, Thomas Jungas, Philippe Verbeke, Toni Darville, and David M. Ojcius

University of the Pacific Student Clinical Profit and Loss Report, Nader A. Nadershahi

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A mouse model of human adaptive immune functions: HLA-A2.1-HLA-DR1-transgenic H-2 class I-/class II-knockout mice, Anthony Pajot, Marie-Louise Michel, Nicolas Fazilleau, Veronique Pancre, Claude Auriault, David M. Ojcius, Francois A. Lemonnier, and Yu-Chun Lone

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Comparison of HLA-DR1-directed T cell response induced in HLA-DR1 transgenic mice deficient for murine MHC class II and HLA-DR1 transgenic mice expressing endogenous murine MHC class II molecules, Anthony Pajot, Veronique Pancre, Nicolas Fazilleau, Marie-Louise Michel, Gerhild Angyalosi, David M. Ojcius, Claude Auriault, Francois A. Lemonnier, and Yu-Chun Lone

Current challenges and concepts in the preparation of root canal systems: a review., Ove A. Peters

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An analysis of endodontic treatment with three nickel-titanium rotary root canal preparation techniques., Ove A. Peters, Fred Barbakow, and Christine I. Peters

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On the formulation of pH-sensitive liposomes with long circulation times, Sérgio Simões, João Nuno Moreira, Cristina Fonseca, Nejat Düzgüneş, and Maria C. Pedroso De Lima

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Comparison of the shape parameters of DNA-cationic lipid complexes and model polyelectrolyte-lipid complexes, Yan Sun, Xingju Yu, Yasuyuki Takaoka, Sho Ichi Oh-I, Nejat Düzgüneş, and Sadao Hirota

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Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas gingivalis, Özlem Yilmaz, Thomas Jungas, Philippe Verbeke, and David M. Ojcius