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Theses/Dissertations from 2016

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Thesis - Pacific Access Restricted: A tale of two small oxygenated molecules as told by photoelectron photoion coincidence spectroscopy, Chrissa Michelle Mozaffari Easter

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Thesis - Pacific Access Restricted: Explorations into protein structure with the knob-socket model, Keith Jeffrey Fraga

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Thesis - Pacific Access Restricted: Use of various health care providers and the associated clinical and humanistic outcomes in an ambulatory Medicare population, Yvonne M. Mai

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Dissertation - Pacific Access Restricted: Role of PRAS40 in mammalian target of rapamycin (mTOR) modulation in cancer and insulin resistance, Ritu Malla

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Thesis - Pacific Access Restricted: Catalase-loaded liposomal magnesium phosphate nanoparticles for intracellular protein delivery, Prathyusha Naidu

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Dissertation - Pacific Access Restricted: Characterization of AG10, a potent stabilizer of transthyretin, and its application in enhancing in vivo half-life of therapeutic peptides, Sravan C. Penchala

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Dissertation - Pacific Access Restricted: The Effects of Sea Water Composition and Biological Activity on Individual Sea Spray Aerosols: Determination of Morphology, Composition, Organic Volume Fraction, and Hygroscopicity of Individual Particles Through X-Ray Microscopy, Don Q. Pham

Theses/Dissertations from 2015

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Dissertation - Pacific Access Restricted: Characterization and application of human pluripotent stem cell-derived neurons to evaluate the risk of developmental neurotoxicity with antiepileptic drugs in vitro, William Sam Cao

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Thesis - Pacific Access Restricted: Effect of rutaecarpine on caffeine pharmacokinetics in rats, Rohit Kumar Estari

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Thesis - Pacific Access Restricted: Computational prediction of enhanced solubility of poorly aqueous soluble drugs prepared by hot melt method, Karthik Chalam Kondepudi

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Thesis: Predicting aqueous solubility of pharmaceutical agents by solid dispersion prepared by solvent evaporation method, Karthik Reddy Patlolla

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Dissertation - Pacific Access Restricted: Design and applications of antibody mimics against epidermal growth factor receptor, Sameer Sachdeva

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Dissertation - Pacific Access Restricted: Rational design, characterization and in vivo studies of antibody mimics against HER2, Dan Su

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Thesis - Pacific Access Restricted: Apparent dissolution rate enhancement of poorly-water soluble drugs by adsorption technique, Naresh Kumar Reddy Vutukuru

Theses/Dissertations from 2014

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Dissertation - Pacific Access Restricted: Study of DNA damage on DNA G-quadruplexes and biophysical evaluation of the effects of modified bases (lesions) on their conformation and stability, Manali Aggrawal

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Dissertation - Pacific Access Restricted: Exploring the molecular architecture of proteins: Method developments in structure prediction and design, Archana G. Chavan

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Dissertation - Pacific Access Restricted: Conformationally Controlled Chiral Phenanthrolines for Asymmetric Catalysis, Irina Dotsenko

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Thesis - Pacific Access Restricted: A novel intracellular protein delivery system - Magnesium phosphate nanoparticles with cationic lipid coating for catalase intracellular delivery, Yunzhou Fang

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Dissertation - Pacific Access Restricted: Sex differences in aortic endothelial function of diabetic rats: Possible involvement of superoxide and nitric oxide production, Xiaoyuan Han

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Dissertation - Pacific Access Restricted: RGD based peptide amphiphiles as drug carriers for cancer targeting, Poonam S. Saraf

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Dissertation - Pacific Access Restricted: Mechanism of tamoxifen resistance in breast cancer, Khyati Niral Shah

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Dissertation - Pacific Access Restricted: Mechanistic study of nanoemulsion absorption and its application for permeation enhancement, Yoshiko Katori Stowell

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Thesis - Pacific Access Restricted: Toxicity of Phenolics and Metabolism of their Esters in Lumbricus Terrestris, Willie Tang

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Thesis - Pacific Access Restricted: Synthesis of poly(NIPAM-co-vmbpy) microspheres and transition metal monomers for metallopolymeric material construction, Carolyn Tran-Math

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Thesis - Pacific Access Restricted: Two approaches to the design and synthesis of bimetallic complexes, Yi-Ju Tsai

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Dissertation - Pacific Access Restricted: Study of the aryl hydrocarbon receptor as a target for rational drug design, Jinghang Xie

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Dissertation - Pacific Access Restricted: Synthesis and biophysical evaluation of thiazole orange derivatives as DNA binding ligands, Dazhou Yang

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Dissertation - Pacific Access Restricted: Investigation of the endoplsmic reticulum calcium stores for their potential roles in neuroprotection using the NG115-401L neuronal cell line model, Changfeng Zhang

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Dissertation - Pacific Access Restricted: Exploring the effects of 5-HT2A and AMPA receptors on brain 5-HT via a mechanism-based pharmacodynamic model, Zhu Zhou

Theses/Dissertations from 2013

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Dissertation - Pacific Access Restricted: Very accurate gas-phase thermochemistry through photoelectron photoion coincidence (PEPICO) spectroscopy, Sampada N. Borkar

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Dissertation - Pacific Access Restricted: Interactions of small molecules with duplex DNA and lesion containing G-quadruplex DNA, Priyanka Chitranshi

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Dissertation - Pacific Access Restricted: Investigation and characterization of the Direct Analysis in Real Time helium metastable beam open-air ion source: Mechanism of ionization, fluid dynamic visualization, and applications, Matthew Earl Curtis

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Dissertation: Turning stealth liposomes into cationic liposomes for anticancer drug delivery, Vijay Gyanani

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Dissertation - Pacific Access Restricted: Sublingual drug delivery: In vitro-in vivo correlation, Navdeep Kaur

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Dissertation - Pacific Access Restricted: Molecule recognition of nucleic acids, nucleosides, nucleotides, and their derivatives, Wanbo Liu

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Dissertation - Pacific Access Restricted: Fliposomes: pH-sensitive liposomes comprising novel trans-2-aminocyclohexanol-based amphiphiles as conformational switches for the liposome mebrane, Xin Liu

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Thesis - Pacific Access Restricted: Human Cytochrome P450 3A4 Over-Expressing IEC-18 and MDCK Cell Lines as an In-Vitro Model to Assess Gut Permeability and the Enzyme Metabolism, Swathi Vangala

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Dissertation - Pacific Access Restricted: Mechanistic study of aryl hydrocarbon receptor nuclear translocator (ARNT)-mediated signaling, Yu Wang

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Dissertation - Pacific Access Restricted: New quinazoline analogues as NF-κB activation inhibitors, Lu Xu

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Dissertation - Pacific Access Restricted: Sex differences in mesenteric endothelial function of streptozotocin-induced diabetic rats: The role of endothelium-derived relaxing factors, Rui Zhang

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Dissertation - Pacific Access Restricted: Synthesis and conformational study of trans-2-aminocyclohexanol-based pH-triggered molecular switches and their application in gene delivery, Yu Zheng

Theses/Dissertations from 2012

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Thesis - Pacific Access Restricted: Synthesis and mass spectrometry studies of oligopeptides, Ashish Sawhney

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Dissertation - Pacific Access Restricted: Exploring the effect of alpha2 receptor on brain 5-HT via a mechanism-based pharmacodynamic model, Jingjing Sun

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Dissertation - Pacific Access Restricted: Performance and mechanism on a high durable silica alumina based cementitious material composed of coal refuse and coal combustion byproducts, Yuan Yao

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Dissertation - Pacific Access Restricted: Synthesis and applications of functional magnetic polymer beads; synthesis and mass spectrometry analysis of model peptides, Xiaoning Zhao

Theses/Dissertations from 2011

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Dissertation - Pacific Access Restricted: Macrocyclic chemistry: Part I - Characterization of a mixed-valence di-iron complex and synthesis of a new poly-iron complex. Part II - Synthesis, characterization of new diphosphoester macrocyclic polyethers, Son Xuan Hoang

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Thesis - Pacific Access Restricted: Preparation of amorphous forms to increase the solubility of poorly soluble drugs using spray drying, Vijaysri Nannapaneni

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Dissertation - Pacific Access Restricted: The discovery and anticancer preclinical investigation of novel piperazinylpyrimidine derivatives designed to target the human kinome, Hassan M. Shallal

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Dissertation - Pacific Access Restricted: Mechanisms of polymer adsorption in nanoparticle stabilization for poorly water soluble compounds, Lauren Sample Wiser

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Dissertation - Pacific Access Restricted: Post-translational modifications of SEL24K from salmon eggs and ZPA from Xenopus laevis eggs, Liang Zhao

Theses/Dissertations from 2010

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Dissertation - Pacific Access Restricted: Structure, secretion, and proteolysis study of MBP-containing heterologous proteins in Pichia pastoris, Zhiguo Li

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Dissertation - Pacific Access Restricted: Mucoadhesive controlled release ciprofloxacin nanoparticles for pulmonary delivery, Sujata S. Mudumba

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Dissertation - Pacific Access Restricted: Studies on thermochemical properties of small organic molecules by mass spectrometry in relation to computational chemistry, Sumit Mukherjee

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Dissertation - Pacific Access Restricted: Development of an in vitro dissolution model to predict the in vivo behavior of poorly soluble compounds, Saroj Vangani

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Thesis - Pacific Access Restricted: Effects of Ainp2 and beta-tubulin on the Arnt-dependent signaling pathways, Tianmin Zhang

Theses/Dissertations from 2009

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Dissertation - Pacific Access Restricted: A pharmacodynamic model of the role of 5-HT2A and GABAA receptors in the delay in the onset of action of SSRIS, Patrick G. Chan

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Dissertation - Pacific Access Restricted: Electrophysiological studies of the interaction between ciprofloxacin and biphenylacetic acid at neuronal receptors and ion channels, Ryoko Hirakawa

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Thesis - Pacific Access Restricted: Gender differences in aortic endothelial function in a rat model of streptozotocin-induced diabetes : possible role of superoxide and cyclooxygenase, Avantika Kekatpure

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Dissertation - Pacific Access Restricted: Binding induced enzyme activated methotrexate-α-peptide prodrugs for integrin targeted drug delivery, Phanidhara R. Kotamraj

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Dissertation - Pacific Access Restricted: The effect of estrogen on intracellular calcium homeostasis in human endothelial cells, Der Thor

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Dissertation - Pacific Access Restricted: A patient-perspective approach to Medicare Part D prescription drug plan costs, Mark P. Walberg

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Dissertation - Pacific Access Restricted: Molecular interactions of biologically active derivatives of sulfamide with pharmaceutical polymers in solid state, Noymi Yam

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Dissertation - Pacific Access Restricted: Leucine-aspartic acid-valine sequence as targeting ligand & drug carrier for doxorubicin delivery to melanoma cells, Sha Zhong

Theses/Dissertations from 2008

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Thesis - Pacific Access Restricted: Evaluation of heart failure clinic alternative-clinician effectiveness study, Veronica Tovar Bandy

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Dissertation - Pacific Access Restricted: Novel folate amphiphile conjugates for targeted drug delivery, Shiladitya Bhattacharya

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Dissertation - Pacific Access Restricted: Synthesis, characterization, and application of novel multifunctional oligosaccharide tags, Nandkishor S. Chindarkar

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Thesis - Pacific Access Restricted: The role of Ryanodine receptors in neuronal calcium signaling, Rui Cui

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Dissertation - Pacific Access Restricted: Examination of posterior predictive check and bootstrap as population model validation tools, Amit V. Desai

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Dissertation - Pacific Access Restricted: Gender difference in rat and rabbit aortic vasodilation after acute treatment with high glucose, Aditya A. Goel

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Dissertation - Pacific Access Restricted: Sublingual drug delivery: In vitro characterization of barrier properties and prediction of permeability, Tarun Goswami

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Thesis - Pacific Access Restricted: Overexpression of active AKT3 induces differential binding of coregulator proteins to the estrogen receptor as a possible mechanism of Tamoxifen resistance, Muhammad A. Hagras

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Thesis - Pacific Access Restricted: Ryanodine receptors in calcium signaling pathways, Yiming Li

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Dissertation - Pacific Access Restricted: Investigation of the role of CyP40 in the aryl hydrocarbon receptor signaling pathway, Tony C. Luu

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Dissertation - Pacific Access Restricted: Mechanism of action of potential anticancer drugs, Smita S. Matkar

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Dissertation - Pacific Access Restricted: Liposome drug delivery systems for anticancer agents, Huizhen Zhang

Theses/Dissertations from 2007

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Thesis - Pacific Access Restricted: An electrophysiological study of the effects of resveratrol and catechin at GABAa receptors, Jennifer C. Harr

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Dissertation - Pacific Access Restricted: An investigation of the neuroprotective properties of fenamate NSAIDs, against experimental model of ischemic stroke, Parto S. Khanasari

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Dissertation - Pacific Access Restricted: An investigation of the neuroprotective properties of fenamate NSAIDs, against experimental models of ischemic stroke, Parto S. Khansari

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Dissertation - Pacific Access Restricted: Drug permeability across the buccal mucosa: Role of ionized species activity and development of a predictive model, Amit Kokate

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Dissertation: Optimization of porcine buccal mucosa for in vitro evaluation, Upendra D. Kulkarni

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Dissertation - Pacific Access Restricted: Factors contributing to and predictive models for drugs exhibiting negative food effects of unknown mechanisms, Venugopal P. Marasanapalle

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Dissertation - Pacific Access Restricted: Pharmacoeconomic analysis of antihypertensive treatment in a population with type 2 diabetes, Rajul Arvind Patel

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Dissertation - Pacific Access Restricted: Intracellular delivery of rabbit monoclonal antibody, Qi Qian

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Thesis - Pacific Access Restricted: Trans-2-aminocyclohexanol as a pH-sensitive conformation switch in liposomes, Ningrong Zhang

Theses/Dissertations from 2006

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Dissertation - Pacific Access Restricted: Study of pharmacological and physiological factors regulating store operated calcium channels in a neuronal cell line, Diptiman Dipen Bose

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Dissertation - Pacific Access Restricted: Synthesis and studies of carbohydrate mimetics as glycosidase inhibitors and molecular switches, Barbora Brazdova

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Thesis - Pacific Access Restricted: Studies on the detection of nucleotides and oligonucleotides by mass spectrometry, Eric H. Chen

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Dissertation - Pacific Access Restricted: Ortho ester-based pH-sensitive cationic lipoplexes for gene delivery, Haigang Chen

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Dissertation - Pacific Access Restricted: Investigation and modulation of the aryl hydrocarbon receptor nuclear translocator-dependent signaling mechanisms, Kyle Andrew Jensen

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Dissertation - Pacific Access Restricted: Study of Arnt-interacting proteins on Arnt-dependent signaling pathways, Yi Li

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Dissertation - Pacific Access Restricted: Exploring the time course of brain 5-hydroxytryptamine via mechanism-based pharmacokinetic-pharmacodynamic modeling, Kenneth T. Luu

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Dissertation - Pacific Access Restricted: Studies of CyP40 and β-tubulin in the Arnt-dependent signaling pathways, Xiaodong Wang

Theses/Dissertations from 2005

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Thesis - Pacific Access Restricted: Effect of Estrogen on LPS-induced human endothelial cell adhesion moledule expression and calcium signaling, Rohini-Ann Franco

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Dissertation - Pacific Access Restricted: Mechanistic study of bovine insulin fibril formation, Emily Ha

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Thesis - Pacific Access Restricted: Artificial neural networks for cardiovascular risk, cardiovascular fitness and ankle-brachial index, Ninad Mohan Patil

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Thesis - Pacific Access Restricted: DEVELOPMENT OF A LC/MS/MS ENZYME METHOD FOR N8 - ACETYLSPERMIDINE MEASUREMENTS IN ENZYME ASSAYS, Jennifer Huiqin Tang

Theses/Dissertations from 2004

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Thesis - Pacific Access Restricted: Evaluation of bootstrapping as a validation technique for population pharmacokinetic models, Mohammed Fawzi Al-otoum

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Dissertation - Pacific Access Restricted: De novo peptide sequencing of spider silk proteins by mass spectrometry and discovery of novel fibroin genes, Xiaoyi Hu

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Thesis - Pacific Access Restricted: Mechanism(s) involved in the transport of Fenretinide across Caco-2 monolayers, Amit Kokate

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Dissertation - Pacific Access Restricted: Genetic and epigenetic mechanisms of paclitaxel resistance in non small cell lung cancer cells, Shanthala Padar