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Theses/Dissertations from 2014

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Dissertation - Pacific Access Restricted: Synthesis and biophysical evaluation of thiazole orange derivatives as DNA binding ligands, Dazhou Yang

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Dissertation - Pacific Access Restricted: Investigation of the endoplsmic reticulum calcium stores for their potential roles in neuroprotection using the NG115-401L neuronal cell line model, Changfeng Zhang

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Dissertation - Pacific Access Restricted: Exploring the effects of 5-HT2A and AMPA receptors on brain 5-HT via a mechanism-based pharmacodynamic model, Zhu Zhou

Theses/Dissertations from 2013

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Dissertation - Pacific Access Restricted: Very accurate gas-phase thermochemistry through photoelectron photoion coincidence (PEPICO) spectroscopy, Sampada N. Borkar

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Dissertation - Pacific Access Restricted: Interactions of small molecules with duplex DNA and lesion containing G-quadruplex DNA, Priyanka Chitranshi

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Dissertation - Pacific Access Restricted: Investigation and characterization of the Direct Analysis in Real Time helium metastable beam open-air ion source: Mechanism of ionization, fluid dynamic visualization, and applications, Matthew Earl Curtis

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Dissertation: Turning stealth liposomes into cationic liposomes for anticancer drug delivery, Vijay Gyanani

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Dissertation - Pacific Access Restricted: Sublingual drug delivery: In vitro-in vivo correlation, Navdeep Kaur

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Dissertation - Pacific Access Restricted: Molecule recognition of nucleic acids, nucleosides, nucleotides, and their derivatives, Wanbo Liu

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Dissertation - Pacific Access Restricted: Fliposomes: pH-sensitive liposomes comprising novel trans-2-aminocyclohexanol-based amphiphiles as conformational switches for the liposome mebrane, Xin Liu

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Thesis - Pacific Access Restricted: Human Cytochrome P450 3A4 Over-Expressing IEC-18 and MDCK Cell Lines as an In-Vitro Model to Assess Gut Permeability and the Enzyme Metabolism, Swathi Vangala

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Dissertation - Pacific Access Restricted: Mechanistic study of aryl hydrocarbon receptor nuclear translocator (ARNT)-mediated signaling, Yu Wang

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Dissertation - Pacific Access Restricted: New quinazoline analogues as NF-κB activation inhibitors, Lu Xu

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Dissertation - Pacific Access Restricted: Sex differences in mesenteric endothelial function of streptozotocin-induced diabetic rats: The role of endothelium-derived relaxing factors, Rui Zhang

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Dissertation - Pacific Access Restricted: Synthesis and conformational study of trans-2-aminocyclohexanol-based pH-triggered molecular switches and their application in gene delivery, Yu Zheng

Theses/Dissertations from 2012

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Thesis - Pacific Access Restricted: Synthesis and mass spectrometry studies of oligopeptides, Ashish Sawhney

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Dissertation - Pacific Access Restricted: Exploring the effect of alpha2 receptor on brain 5-HT via a mechanism-based pharmacodynamic model, Jingjing Sun

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Dissertation - Pacific Access Restricted: Performance and mechanism on a high durable silica alumina based cementitious material composed of coal refuse and coal combustion byproducts, Yuan Yao

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Dissertation - Pacific Access Restricted: Synthesis and applications of functional magnetic polymer beads; synthesis and mass spectrometry analysis of model peptides, Xiaoning Zhao

Theses/Dissertations from 2011

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Dissertation - Pacific Access Restricted: Macrocyclic chemistry: Part I - Characterization of a mixed-valence di-iron complex and synthesis of a new poly-iron complex. Part II - Synthesis, characterization of new diphosphoester macrocyclic polyethers, Son Xuan Hoang

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Thesis - Pacific Access Restricted: Preparation of amorphous forms to increase the solubility of poorly soluble drugs using spray drying, Vijaysri Nannapaneni

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Dissertation - Pacific Access Restricted: The discovery and anticancer preclinical investigation of novel piperazinylpyrimidine derivatives designed to target the human kinome, Hassan M. Shallal

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Dissertation - Pacific Access Restricted: Mechanisms of polymer adsorption in nanoparticle stabilization for poorly water soluble compounds, Lauren Sample Wiser

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Dissertation - Pacific Access Restricted: Post-translational modifications of SEL24K from salmon eggs and ZPA from Xenopus laevis eggs, Liang Zhao

Theses/Dissertations from 2010

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Dissertation - Pacific Access Restricted: Structure, secretion, and proteolysis study of MBP-containing heterologous proteins in Pichia pastoris, Zhiguo Li

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Dissertation - Pacific Access Restricted: Mucoadhesive controlled release ciprofloxacin nanoparticles for pulmonary delivery, Sujata S. Mudumba

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Dissertation - Pacific Access Restricted: Studies on thermochemical properties of small organic molecules by mass spectrometry in relation to computational chemistry, Sumit Mukherjee

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Dissertation - Pacific Access Restricted: Development of an in vitro dissolution model to predict the in vivo behavior of poorly soluble compounds, Saroj Vangani

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Thesis - Pacific Access Restricted: Effects of Ainp2 and beta-tubulin on the Arnt-dependent signaling pathways, Tianmin Zhang

Theses/Dissertations from 2009

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Dissertation - Pacific Access Restricted: A pharmacodynamic model of the role of 5-HT2A and GABAA receptors in the delay in the onset of action of SSRIS, Patrick G. Chan

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Dissertation - Pacific Access Restricted: Electrophysiological studies of the interaction between ciprofloxacin and biphenylacetic acid at neuronal receptors and ion channels, Ryoko Hirakawa

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Thesis - Pacific Access Restricted: Gender differences in aortic endothelial function in a rat model of streptozotocin-induced diabetes : possible role of superoxide and cyclooxygenase, Avantika Kekatpure

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Dissertation - Pacific Access Restricted: Binding induced enzyme activated methotrexate-α-peptide prodrugs for integrin targeted drug delivery, Phanidhara R. Kotamraj

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Dissertation - Pacific Access Restricted: The effect of estrogen on intracellular calcium homeostasis in human endothelial cells, Der Thor

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Dissertation - Pacific Access Restricted: A patient-perspective approach to Medicare Part D prescription drug plan costs, Mark P. Walberg

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Dissertation - Pacific Access Restricted: Molecular interactions of biologically active derivatives of sulfamide with pharmaceutical polymers in solid state, Noymi Yam

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Dissertation - Pacific Access Restricted: Leucine-aspartic acid-valine sequence as targeting ligand & drug carrier for doxorubicin delivery to melanoma cells, Sha Zhong

Theses/Dissertations from 2008

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Thesis - Pacific Access Restricted: Evaluation of heart failure clinic alternative-clinician effectiveness study, Veronica Tovar Bandy

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Dissertation - Pacific Access Restricted: Novel folate amphiphile conjugates for targeted drug delivery, Shiladitya Bhattacharya

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Dissertation - Pacific Access Restricted: Synthesis, characterization, and application of novel multifunctional oligosaccharide tags, Nandkishor S. Chindarkar

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Thesis - Pacific Access Restricted: The role of Ryanodine receptors in neuronal calcium signaling, Rui Cui

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Dissertation - Pacific Access Restricted: Examination of posterior predictive check and bootstrap as population model validation tools, Amit V. Desai

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Dissertation - Pacific Access Restricted: Gender difference in rat and rabbit aortic vasodilation after acute treatment with high glucose, Aditya A. Goel

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Dissertation - Pacific Access Restricted: Sublingual drug delivery: In vitro characterization of barrier properties and prediction of permeability, Tarun Goswami

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Thesis - Pacific Access Restricted: Overexpression of active AKT3 induces differential binding of coregulator proteins to the estrogen receptor as a possible mechanism of Tamoxifen resistance, Muhammad A. Hagras

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Thesis - Pacific Access Restricted: Ryanodine receptors in calcium signaling pathways, Yiming Li

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Dissertation - Pacific Access Restricted: Investigation of the role of CyP40 in the aryl hydrocarbon receptor signaling pathway, Tony C. Luu

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Dissertation - Pacific Access Restricted: Mechanism of action of potential anticancer drugs, Smita S. Matkar

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Dissertation - Pacific Access Restricted: Liposome drug delivery systems for anticancer agents, Huizhen Zhang

Theses/Dissertations from 2007

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Thesis - Pacific Access Restricted: An electrophysiological study of the effects of resveratrol and catechin at GABAa receptors, Jennifer C. Harr

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Dissertation - Pacific Access Restricted: An investigation of the neuroprotective properties of fenamate NSAIDs, against experimental model of ischemic stroke, Parto S. Khanasari

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Dissertation - Pacific Access Restricted: An investigation of the neuroprotective properties of fenamate NSAIDs, against experimental models of ischemic stroke, Parto S. Khansari

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Dissertation - Pacific Access Restricted: Drug permeability across the buccal mucosa: Role of ionized species activity and development of a predictive model, Amit Kokate

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Dissertation: Optimization of porcine buccal mucosa for in vitro evaluation, Upendra D. Kulkarni

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Dissertation - Pacific Access Restricted: Factors contributing to and predictive models for drugs exhibiting negative food effects of unknown mechanisms, Venugopal P. Marasanapalle

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Dissertation - Pacific Access Restricted: Pharmacoeconomic analysis of antihypertensive treatment in a population with type 2 diabetes, Rajul Arvind Patel

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Dissertation - Pacific Access Restricted: Intracellular delivery of rabbit monoclonal antibody, Qi Qian

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Thesis - Pacific Access Restricted: Trans-2-aminocyclohexanol as a pH-sensitive conformation switch in liposomes, Ningrong Zhang

Theses/Dissertations from 2006

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Dissertation - Pacific Access Restricted: Study of pharmacological and physiological factors regulating store operated calcium channels in a neuronal cell line, Diptiman Dipen Bose

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Dissertation - Pacific Access Restricted: Synthesis and studies of carbohydrate mimetics as glycosidase inhibitors and molecular switches, Barbora Brazdova

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Thesis - Pacific Access Restricted: Studies on the detection of nucleotides and oligonucleotides by mass spectrometry, Eric H. Chen

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Dissertation - Pacific Access Restricted: Ortho ester-based pH-sensitive cationic lipoplexes for gene delivery, Haigang Chen

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Dissertation - Pacific Access Restricted: Investigation and modulation of the aryl hydrocarbon receptor nuclear translocator-dependent signaling mechanisms, Kyle Andrew Jensen

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Dissertation - Pacific Access Restricted: Study of Arnt-interacting proteins on Arnt-dependent signaling pathways, Yi Li

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Dissertation - Pacific Access Restricted: Exploring the time course of brain 5-hydroxytryptamine via mechanism-based pharmacokinetic-pharmacodynamic modeling, Kenneth T. Luu

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Dissertation - Pacific Access Restricted: Studies of CyP40 and β-tubulin in the Arnt-dependent signaling pathways, Xiaodong Wang

Theses/Dissertations from 2005

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Thesis - Pacific Access Restricted: Effect of Estrogen on LPS-induced human endothelial cell adhesion moledule expression and calcium signaling, Rohini-Ann Franco

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Dissertation - Pacific Access Restricted: Mechanistic study of bovine insulin fibril formation, Emily Ha

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Thesis - Pacific Access Restricted: Artificial neural networks for cardiovascular risk, cardiovascular fitness and ankle-brachial index, Ninad Mohan Patil

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Thesis - Pacific Access Restricted: DEVELOPMENT OF A LC/MS/MS ENZYME METHOD FOR N8 - ACETYLSPERMIDINE MEASUREMENTS IN ENZYME ASSAYS, Jennifer Huiqin Tang

Theses/Dissertations from 2004

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Thesis - Pacific Access Restricted: Evaluation of bootstrapping as a validation technique for population pharmacokinetic models, Mohammed Fawzi Al-otoum

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Dissertation - Pacific Access Restricted: De novo peptide sequencing of spider silk proteins by mass spectrometry and discovery of novel fibroin genes, Xiaoyi Hu

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Thesis - Pacific Access Restricted: Mechanism(s) involved in the transport of Fenretinide across Caco-2 monolayers, Amit Kokate

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Dissertation - Pacific Access Restricted: Genetic and epigenetic mechanisms of paclitaxel resistance in non small cell lung cancer cells, Shanthala Padar

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Thesis - Pacific Access Restricted: Pharmacological regulators of T cell calcium stores, Alister Michael Peters

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Dissertation - Pacific Access Restricted: Regulation of differentiation of murine erythroleukemia cells by HMBA and its deacetylated metabolites, Vanishree Rajagopalan

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Dissertation - Pacific Access Restricted: Arg-Gly-Asp (RGD) conjugated aliphatic acids as micellar drug carrier for targeted drug delivery, Steve I. Shen

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Dissertation - Pacific Access Restricted: Evaluating the effects of HMG -CoA reductase inhibitors on C -reactive protein, butyrylcholinesterase, and lipids, Annie Heekyung Shinn

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Dissertation - Pacific Access Restricted: Growth factor expression and release in the ischemic heart, Lynette Christine Vos

Theses/Dissertations from 2003

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Dissertation - Pacific Access Restricted: Body weight -supported gait training in poststroke hemiparetic patients undergoing treatment with serotonin reuptake inhibitors: A pilot study, Annie Patrice Burke-Doe

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Thesis - Pacific Access Restricted: In vitro permeability studies of antitumor compounds, thioxanthones across two model barriers, and their availability in vivo, Venugopal P. Marasanapalle

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Dissertation - Pacific Access Restricted: Mechanistic studies on protein factors dependent formation of the aryl hydrocarbon receptor -DNA complex, Premnath Vithal Shetty

Theses/Dissertations from 2002

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Thesis - Pacific Access Restricted: Role of ryanodine receptors in neuronal calcium signalling and growth control, Diptiman Dipen Bose

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Dissertation - Pacific Access Restricted: Synthesis of saccharomimetic fucopyranosyl -substituted urethanes and ureas from glycopyranosyl nitromethanes and cyanides, Pasit Phiasivongsa

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Dissertation - Pacific Access Restricted: Poly(amino acid) as a targeting drug delivery carrier, Andrea Kay Wamsley

Theses/Dissertations from 2001

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Thesis - Pacific Access Restricted: Design and synthesis of aryl hydrocarbon receptor fusion proteins for polyclonal antibodies production and cellular delivery, Bhagyashree Yogesh Bhagwat

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Dissertation - Pacific Access Restricted: Transbuccal drug delivery: In vitro characterization of transport pathway of buspirone and bioadhesive drug delivery system, Kondamraj Birudaraj

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Dissertation - Pacific Access Restricted: Iontophoretic drug transport through hydrogel membranes, Pei Yang

Theses/Dissertations from 2000

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Dissertation - Pacific Access Restricted: New polyamine analogues as potential antineoplastic agents, Alina Chen

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Dissertation - Pacific Access Restricted: Population pharmacokinetics and pharmacodynamics of zidovudine, didanosine and nevirapine in children and adolescents with advanced HIV disease, Yong Ho Kim

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Thesis - Pacific Access Restricted: Bioactivation of diacetyldapsone in cultured lung cells, Dipali Nimbalkar

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Thesis - Pacific Access Restricted: Modified alginates as a matrix for gene transfection in a HeLa cell model, Kiran Padmanabhan

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Dissertation - Pacific Access Restricted: In vitro study of transbuccal drug delivery systems: Mucoadhesion of a novel bioadhesive and permeation of zalcitabine, Jun Xiang

Theses/Dissertations from 1999

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Dissertation - Pacific Access Restricted: Development and evaluation of a population pharmacokinetic model for phenytoin in patients with impaired liver function, Tina Hsiao-Tin Hui

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Dissertation - Pacific Access Restricted: Effects of acetylated polyamines on differentiation of Cloudman S91 melanoma cells, Ramana Rao Malladi

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Thesis - Pacific Access Restricted: Comparison of the effect of acetylated polyamines and N⁸-acetylspermidine deacetylase inhibitor, APAH, on LS180 and multidrug resistant cells, Wenxian Mao

Theses/Dissertations from 1998

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Thesis - Pacific Access Restricted: Pharmacokinetic modeling of vancomycin in children, pre-adolescent, and adolescent patients : development, assessment, and application, Yousif Abdu Asiri

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Thesis - Pacific Access Restricted: Effect of ethyl oleate and oleic anhydride on metronidazole release from poly(ortho esters) films, Kamalika Chaudhury

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Thesis - Pacific Access Restricted: The analgesic efficacy and therapeutic onset of analgesia of intravenous and intramuscular ketorolac (15 mg and 30 mg), and oral ibuprofen 800 mg in the emergency room : a comparative study, Mohdhar Jeilan Habib

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Thesis - Pacific Access Restricted: Preparation and evaluation of poly (ortho esters) microspheres containing 5-fluorouracil, Yuh-Herng E. Lin