Theses/Dissertations from 2024
Dissertation: A Novel Drug Delivery System for Controlled and Extended Release of Naloxone, Hala Aldawod
Dissertation: Impact of Drug-Polymer Interactions on Stability in Simvastatin-Based Amorphous Solid Dispersions, Charina Lampa
Dissertation: Structural and Functional Studies of the Human Members of the Macrophage Migration Inhibitory Factor Family, Andrew Parkins
Dissertation: An Empirical Predictive Model for Determining the Aqueous Solubility of BCS Class IV Drugs in Amorphous Solid Dispersions, Sridivya Raparla
Dissertation: Synthesis of Hydroxycinnamate Derivatives and Characterization of Bioactivity as Radical Scavengers and α-Glucosidase Inhibitors, Cate Simmermaker
Dissertation: Elaboration of Diquinanes to Access Trifunctional Angular Triquinanes and Designed DNA Polymerase α Inhibitors, Spencer M. Webber
Thesis: Impact of a Culturally-Grounded and Interprofessional Approach to Managing Latino/Hispanic Patients at Risk for or Diagnosed with Type 2 Diabetes Mellitus: A Pilot Study, Jahnavi Yalamanchili
Theses/Dissertations from 2023
Thesis: REMOTE AMBIENT AEROSOLS FOUND IN THE SOUTHERN GREAT PLAINS AND EASTERN NORTH ATLANTIC: A COMPREHENSIVE ANALYSIS OF OPTICAL BEHAVIOR AND AEROSOL-CLOUD INTERACTION, Daniel J. Bonanno
Dissertation: Development of Multivalent DNA-Peptide Nucleosome Mimetics and Multi-Domain Protein Inhibitors That Directly or Indirectly Target the E3 Ligase UHRF1, Li Gu
Dissertation: Enhancing the half-life of Interleukin 2 by conjugation to the Transthyretin Ligand, TLHE And Enhancing the efficacy of peptides that inhibit COVID 19 viral entry, Arjun D. Patel
Dissertation: ROLE OF CYSTEINE REDOX STATE IN ALTERING THE EPITHELIAL-MESENCHYMAL TRANSITION IN LUNG CANCER, Md Anisur Rahman
Dissertation: Evaluation of Human Stem Cell-Derived Neurons in 2D and 3D Cultures for Neurodevelopmental Studies, Epilepsy Disease Modeling and Drug Discovery, Hamed Salmanzadeh-Dozdabi
Dissertation: Targeting ribonucleotide reductase for breast cancer treatment, Nahid Sultana
Thesis: Chemically Mediated Algal-Bacterial Interactions: Promotion & Inhibition, Kara Talbott
Thesis: Investigating bZip Recognition of DNA Sequences Through a Knob-Socket Perspective, Aaron Tran
Dissertation: Influence of Female Sex Hormones on GHB Toxicokinetics and Regulation of MCTs and SMCTs, Hao Wei
Dissertation: The Degradation Mechanisms of Aryl Hydrocarbon Receptor in Human Lung Epithelial Carcinoma A549 Cells, Rui Xiong
Theses/Dissertations from 2022
Dissertation: INCORPORATING GLUTAMIC ACID-VALINE-CITRULLINE LINKER IN TRIFUNCTIONAL MOLECULES TARGETING PSMA ENSURES ENHANCED STABILITY, SAFETY, AND EFFICACY IN MOUSE MODEL OF PROSTATE CANCER, Toufiq Ul Amin
Thesis: The Vagabond Flourine Atom Revisited: Dissociative Photoionization of Tri- and Pentafluoropropene, Jessica K. De La Cruz
Thesis: MICROBIAL COMMUNITY ANALYSIS: BIOFILM INHIBITION & ALGAE ASSOCIATED COMMUNITY STRUCTURE, Michelle V. Fong
Thesis: Optimization of the structure of TTR Ligands for Half-life Extension (TLHE), Guanming Jiang
Thesis: GC/MS AND LC/MS APPROACHES TO CHEMICAL COMMUNICATION IN PLANTS AND MARINE CYANOBACTERIA, Carolyn Keim
Dissertation: PERIPHERALLY RESTRICTED DELIVERY SYSTEM PROVIDES INSIGHTS ON THE ROLE OF CNS IN PRECIPITATING OPIOID-INDUCED CONSTIPATION, Dengpan Liang
Thesis: Investigation of CDK8 inhibitor Q-12 effects on CDK8 and CDK8 substrates in triple negative breast cancer cell line MDA-MB-468, Shengxi Li
Dissertation: PEPTOID FRAGMENTATION PATHWAYS BY TANDEM MASS SPECTROMETRY STUDIES, Yadwinder Singh Mann
Dissertation: THERMODYNAMIC MECHANISMS OF HELIX STABILIZATION IN A MODEL PEPTIDE AND PROTEIN, Ryan Murray
Dissertation: THE COMBINATORY EFFECTS OF PEDIATRIC OBESITY AND ONTOGENY ON MONOCARBOXYLATE TRANSPORTER EXPRESSION IN TISSUES OF DRUG DISPOSITION, Michael Ng
Thesis: Optimizing the human aryl hydrocarbon receptor (hAHR) expression in Pichia pastoris, junyu qian
Dissertation: PERIPHERALLY RESTRICTED OPIOID CONJUGATES AND ITS USE AS PHARMACOLOGICAL PROBES AND POTENTIAL THERAPEUTICS, Md Tariqul Haque Tuhin
Thesis: EXPRESSION OF MOUSE FULL-LENGTH ARYL HYDROCARBON RECEPTOR AND HUMAN ARYL HYDROCARBON RECEPTOR LIGAND BINDING DOMAIN IN PICHIA PASTORIS, Yiyuan Wang
Dissertation: GAS-PHASE ACID-BASE PROPERTIES AND CONFORMATIONS OF OLIGOPEPTIDES THROUGH MASS SPECTROMETRY AND COMPUTATIONAL STUDIES, Yuntao Zhang
Theses/Dissertations from 2021
Dissertation: Translationally-transformed coupled-cluster theory for periodic systems, Boris Daniel Gutierrez-Cortes
Thesis: BAYESIAN-DERIVED VANCOMYCIN AUC24H THRESHOLD FOR NEPHROTOXICITY IN SPECIAL POPULATIONS, Dan Ho
Thesis: Investigating the Specificity of Coiled-Coil Recognition, Melina Huey
Dissertation: HARNESSING TRANSTHYRETIN TO ENHANCE THE IN VIVO HALF-LIFE OF HUMAN INTERLEUKIN-2 (IL-2), Fang Liu
Thesis: Development of Linked-Domain Protein Inhibitors of the E2-Conjugating Enzyme Ube2D, Anneroos E. Nederstigt
Dissertation: IMPACT OF 17-BETA ESTRADIOL AND MODERATE-INTENSITY EXERCISE ON MESENTERIC ARTERIAL FUNCTION OF UC DAVIS TYPE-2 DIABETES MELLITUS RATS, Md Rahatullah Razan
Dissertation: SYNTHESIS AND CONFORMATIONAL STUDY OF TRIAZOLYLCYCLOHEXANOLS AND TRANS-2-(AZAARYLSULFANYL)-CYCLOHEXANOLS, Mulinde R. Ruyonga
Thesis: EXPLORING THE RELATIONSHIP BETWEEN GRIT, WORK ENGAGEMENT, AND CAREER SUCCESS AMONG U.S. PHARMACISTS, Nareeta A. Sharma
Dissertation: IN VITRO COMPARATIVE STUDY OF THE BINDING AFFINITY AND TARGETED-DRUG DELIVERY EFFICIENCY OF EGFR-TARGETING PEPTIDES, Jingda Wang
Dissertation: POST-TRANSLATIONAL MODIFICATION AND DEGRADATION MECHANISMS OF THE ARYL HYDROCARBON RECEPTOR, Yujie Yang
Thesis: DEVELOPMENT OF MIRIPLATIN-LOADED NANOPARTICLES AGAINST NON-SMALL CELL LUNG CANCER, Zhongyue Yuan
Theses/Dissertations from 2020
Dissertation: REGULATION OF INTRACELLULAR ARYL HYDROCARBON RECEPTOR PROTEIN LEVELS, Jinyun Chen
Thesis: Effects of Chronic Energy Drink Consumption on Cardiometabolic Endpoints, May Chen
Thesis: midazole-based pH-sensitive Convertible Liposomes for Anticancer Drug Delivery, Ruiqi Huang
Thesis: Multicellular spheroids of A549 and A549-iRFP as an in vitro model of lung cancer, Xinyu Pei
Dissertation: STUDIES ON THE SIZE AND NON-PLANARITY OF AROMATIC STACKING MOIETY ON CONFORMATION SELECTIVITY AND THERMAL STABILIZATION OF G-QUADRUPLEXES, Mandeep Singh
Dissertation: EXPLORATION OF CIS-1,2-DIAMINOCYCLOHEXANE-BASED CONFORMATIONALLY LOCKED CHIRAL LIGANDS IN ASYMMETRIC SYNTHESIS, Carim van Beek
Dissertation: ELEPHANT AND ANCHORS ‒ PHOTOELECTRON PHOTOION COINCIDENCE SPECTROSCOPY OF SMALL OXYGENATED MOLECULES, aPeter Weidner
Thesis: Development of Lipid-based Nano Formulations of Miriplatin Against Lung Cancer, Zizhao Xu
Thesis: Role of Polymer Physicochemical Properties on in vitro Mucoadhesion, Qing Zhang
Theses/Dissertations from 2019
Dissertation: Sexual Dimorphism in Aortic Function of UC Davis Type 2 Diabetes Mellitus Rat Model: Estrogen Specific Responses, Farjana Akther
Thesis: Synthesis and Conformational Studies of Various Amides, Marcos Beltran-Sanchez
Dissertation: The role of sex hormones on monocarboxylate transporter expression in tissues related to drug disposition, Jieyun Cao
Dissertation: Exploring the Molecular Origin of Jet Fuel Thermal Oxidative Deposition Through Statistical Analysis of Mass Spectral Data and Pyrolysis Gas Chromatography/Mass Spectrometry of Deposits, Krege Matthew Christison
Dissertation: Roaming Transition States and Highly Accurate Thermochemistry: A PEPICO Study of Two Small Combustion Systems, Kyle John Covert
Dissertation: Development and Characterization of LDV Peptide Targeted Nanocarriers for Paclitaxel Delivery: A Comparative Study of Micelles, Liposomes and Solid Lipid Nanoparticles, Poonam Dattani
Dissertation: Approaches to the Search of Platinum Anticancer Agents: Derivatizing Current Drugs and Incorporating HDAC Inhibition, Chao Feng
Dissertation: Developing X-ray Spectromicroscopic Techniques to Quantitatively Determine Population Statistics and Individual Particle Composition of Complex Mixed Aerosols, Matthew Fraund
Thesis: Intrapulmonary Inoculation of Multicellular Tumor Spheroids to Construct an Orthotopic Lung Cancer Xenograft Model that Mimics Four Clinical Stages of Non-small Cell Lung Cancer, Yingbo Huang
Thesis: The Effect of Energy Drinks on Cardiovascular Variables: A Randomized Controlled Trial, Cynthia Lee
Thesis: The potency of AG10 in stabilizing transthyretin is driven by interactions mimicking the disease-suppressing T119M variant, Dengpan Liang
Dissertation: A COST CONTROL MODEL FOR INPATIENT MEDICATIONS AMONG ADULTS WITH MENTAL AND BEHAVIORAL HEALTH DISORDERS, Huanan Li
Thesis: Investigating the Effect of Rutaecarpine on the Benzo[a]pyrene-Induced DNA Damage in vitro, You Li
Dissertation: Fliposomes with a pH-sensitive conformational switch for anticancer drug delivery against triple negative breast cancer, Yifan Lu
Dissertation: Development of a new class of ligand-targeted chemotherapeutics with enhanced safety and efficacy profile, Arindom Pal
Dissertation: Knob-socket Investigation of Stability and Specificity in Alpha-helical Secondary and Quaternary Packing Structure, Taylor Renee Rabara
Dissertation: I3: Isomerization of Isomer Ions, Krisztián Gabor Torma
Dissertation: Developing a Rational Peptide Ligand Design Method Using CD13 as a Prototype Target Receptor, Md Zahir Uddin
Dissertation: Lipid-coated Magnesium Phosphate Nanoparticles for Intrapulmonary Protein Delivery in Mice, Mallika Vadlamudi
Dissertation: The role of aryl hydrocarbon receptor (AHR) in drug-drug interaction and the expression of AHR in Pichia Pastoris, Yujuan Zheng
Theses/Dissertations from 2018
Thesis: DNA Lesions Produced from the Reaction of Diols and 5-Formylcytosine and Their Effects on DNA Replication, Brock Allen
Thesis: Investigations on Cancer Cell Biological Effects of CDK8 Inhibitor Q-12, Zhixin Lu
Dissertation: Mechanistic Study of p23-Mediated Aryl Hydrocarbon Receptor Expression, Beverly Pappas
Dissertation: Bimetallic complexes: The fundamental aspects of metal-metal interactions, ligand sterics and application, Michael Bernard Pastor
Dissertation: Development of Novel Phenanthroline and Thiazole Orange Derived G-quadruplex Ligands and Telomerase Inhibitors, Siwen Wang
Thesis: Peptide-drug conjugate for Her2-targeted drug delivery, Yan Wang
Thesis: Influence of the estrous cycle and female sex hormones on GHB toxicokinetics, Hao Wei
Dissertation: Determining the role played by Aryl Hydrocarbon Receptor (AHR) in the colon carcinoma tumor model, Poonam Yakkundi
Dissertation: Computational Methods in Biomolecules:Study of Hydrophilic Interactions in Protein Folding & Constant-pH Molecular Simulation of pH Sensitive Lipid MORC16, Wei Zhang
Dissertation: Design and in vitro characterization of lipids with a pH-sensitive conformational switch and their liposomes for anticancer drug delivery, Shen Zhao
Thesis: RATIONAL DESIGN OF PEPTIDES BINDING TOWARDS HUMAN PD-L1 USING KNOB-SOCKET MODEL, Xingchen Zha
Theses/Dissertations from 2017
Dissertation - Pacific Access Restricted: A Nature Inspired Approach for Enhancing the Efficacy of Anticancer Agents, Wabel Albusairi
Dissertation - Pacific Access Restricted: Effect of Tumor Microenvironmental Conditions on Non Small Cell Lung Cancer, Swetha Arikatla
Thesis - Pacific Access Restricted: Anticholinergic Burden and its Association with Sleep, Craig D. Barker
Thesis: Investigating Secondary Structure Features of YAP1 Protein Fragments Using Molecular Dynamics (MD) and Steered Molecular Dynamics (SMD) Simulations, Ferdiemar Cardenas Guinto Jr.
Thesis - Pacific Access Restricted: Evaluation of In-Vitro Methods that Can Predict In-Vivo Stability of Liposomes, Harshavardan Reddy Gurrala
Thesis: Synthesis of AG10 analogs and optimization of TTR ligands for Half-life enhancement (TLHE) of Peptides, Raghavendra Jampala
Dissertation: Fragment-based Excitonic Coupled-Cluster Theory for Large Chemical Systems, Yuhong Liu
Dissertation: Preclinical evaluation of AG10 for therapeutic use against familial amyloid cardiomyopathy and its application in various other technologies, Mark Russell Miller
Thesis: The Rational Investigation of Anti-Cancer Peptide Specificity using the Knob-Socket Model, Shivarni Patel
Thesis: SOLUBILITY ENHANCEMENT OF MODEL COMPOUNDS, Lavanya Pitani
Thesis - Pacific Access Restricted: Soluble and Functional Overexpression of the Ligand Binding Domain of Mouse Aryl Hydrocarbon Receptor in E.Coli, Himaja Ponnakanti
Thesis: CLINICAL FACTORS ASSOCIATED WITH HEPATITIS C TREATMENT SELECTION IN A VETERANS AFFAIRS POPULATION, Carly Anne Ranson
Thesis - Pacific Access Restricted: The Effects of Dietary Sugar Intake and Type 2 Diabetes on Mesenteric Arterial Function in Rats, Sonali Satish Shaligram
Thesis - Pacific Access Restricted: Overexpression of Human Aryl Hydrocarbon Receptor in E.coli Using Two Different Solubility Enhancing Tags, Sravanthi Tejomurthula
Thesis: Liposome-coated Magnesium Phosphate Nanoparticle for Delivery of Cytochrome C into Lung Cancer Cells A549, Weizhou Yue
Theses/Dissertations from 2016
Dissertation - Pacific Access Restricted: Thermochemical differences in lysine and lysine-homolog containing oligopeptides: Determination of basicity and gas-phase structure through mass spectrometry, infrared spectroscopy, and computational chemistry, Patrick Henry M. Batoon
Thesis - Pacific Access Restricted: Establishment of gas-phase thermochemical values of various small organic compounds and oligopeptides, Zachary Buen
Dissertation - Pacific Access Restricted: First-principle based pharmacokinetic modeling, Jin Dong
