Marcia Mentkowski and Glen Rogers
This publication draws on Alverno’s experience in student and institutional assessment to articulate frameworks for establishing the validity of student learning outcome measures. It tracks how the dynamics of curriculum, teaching, learning, and assessment interact to shape practice-informed meanings for the concept of validity, accommodating both the educational use of performance-based assessments and wider demands for accountability.
Validating college outcomes with self-developed instruments: Issues in maximizing contextual validity
Contextual validity for an instrument requires the integration of the multiplicity of perspectives and purposes into its design and the fidelity of its elicited mode of performance with post-college settings. This document illustrates how the strategies and elements of the contextual validity of specific instruments can be shown by describing and analyzing the history of two instruments.
John C. Livesey, Donald J. Reed, and Lucile F. Adamson
The scientific literature on radiation-protective drugs is reviewed. Emphasis is placed on the mechanisms Involved in determining the sensitivity of biological material to ionizing radiation and mechanisms of chemical radioprotection. In Section 1, the types of radiation are described and the effects of ionizing radiation on biological systems are reviewed. The effects of ionizing radiation are briefly contrasted with the effects of non-Ionizing radiation. Section I reviews the contributions of various natural factors which influence the inherent radiosensitivity of biological systems. Included in the list of these factors are water, oxygen, thiols, vitamins and antioxidants. Brief attention is given to the model describing competition between oxygen and natural radioprotective substances (principally, thiols) In determining the net cellular radiosensitivity. Several theories of the mechanism(s) of action of radioprotective drugs are described In Section 111. These mechanisms include the production of hypoxia, detoxication of radiochemical reactive species, stabilization of the radiobiological target and the enhancement of damage repair processes. Section IV describes the current strategies for the treatment of radiation injury. Likely areas in which fruitful research might be performed are described in Section V. Appendices are devoted to lists of currently-funded research projects Involving chemical radiation protection and a brief compendium of compounds which have been tested for radioprotective activity.
M. W. Anders and John C. Livesey
A selection of books and book chapters written or edited by faculty at the University of the Pacific.
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