Synthesis and characterization of biotin derivatives as multifunctional oligosaccharide tags

Authors

Nandkishor S. ChindarkarFollow
Andreas H. Franz, University of the PacificFollow

Document Type

Article

Publication Title

ARKIVOC

Department

Chemistry

ISSN

1551-7012

Volume

2008

Issue

15

DOI

10.3998/ark.5550190.0009.f03

First Page

21

Last Page

33

Publication Date

1-1-2008

Abstract

The synthesis of novel multifunctional oligosaccharide tags with amino, azido, and alkyne termini is described. Tags with an amino terminus can be introduced into the carbohydrate at the reducing end through reductive amination, while 1,3-dipolar cycloaddition (“click chemistry”) can be used to label azido sugars with oligosaccharide tags having an alkyne terminus and vice versa.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Chindarkar, N. S., & Franz, A. H. (2008). Synthesis and characterization of biotin derivatives as multifunctional oligosaccharide tags. ARKIVOC, 2008(15), 21–33. DOI: 10.3998/ark.5550190.0009.f03
https://scholarlycommons.pacific.edu/cop-facarticles/156