Title

Charcterization of Cysteine Protease Inhibitor (CP8) Virulence Factor in Bovine and Feline Strains of T. Foetus

Poster Number

50

Lead Author Major

Biological Sciences

Format

Poster Presentation

Faculty Mentor Name

Kirkwood Land

Faculty Mentor Department

Biological Sciences

Abstract/Artist Statement

Tritrichomonas foetus is related to the human parasite Trichomonas vaginalis. In T. vaginalis strains Cysteine proteases are thought to be major virulence factors. One such virulence factor is Cysteine Protease 8 (CP8). This study examines the role of CP8 in both bovine and feline clinical isolates. We have obtained samples from cows and cats that presented with clinical disease at the UC Davis Small Animal Hospital and are analyzing the expression of CP8 in all of these isolates. The characterization of this virulence factor will shed light on the pathogenesis of this important veterinary protozoal disease.

Location

Grave Covell

Start Date

21-4-2012 10:00 AM

End Date

21-4-2012 12:00 PM

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Apr 21st, 10:00 AM Apr 21st, 12:00 PM

Charcterization of Cysteine Protease Inhibitor (CP8) Virulence Factor in Bovine and Feline Strains of T. Foetus

Grave Covell

Tritrichomonas foetus is related to the human parasite Trichomonas vaginalis. In T. vaginalis strains Cysteine proteases are thought to be major virulence factors. One such virulence factor is Cysteine Protease 8 (CP8). This study examines the role of CP8 in both bovine and feline clinical isolates. We have obtained samples from cows and cats that presented with clinical disease at the UC Davis Small Animal Hospital and are analyzing the expression of CP8 in all of these isolates. The characterization of this virulence factor will shed light on the pathogenesis of this important veterinary protozoal disease.