Charcterization of Cysteine Protease Inhibitor (CP8) Virulence Factor in Bovine and Feline Strains of T. Foetus
Poster Number
50
Format
Poster Presentation
Faculty Mentor Name
Kirkwood Land
Faculty Mentor Department
Biological Sciences
Abstract/Artist Statement
Tritrichomonas foetus is related to the human parasite Trichomonas vaginalis. In T. vaginalis strains Cysteine proteases are thought to be major virulence factors. One such virulence factor is Cysteine Protease 8 (CP8). This study examines the role of CP8 in both bovine and feline clinical isolates. We have obtained samples from cows and cats that presented with clinical disease at the UC Davis Small Animal Hospital and are analyzing the expression of CP8 in all of these isolates. The characterization of this virulence factor will shed light on the pathogenesis of this important veterinary protozoal disease.
Location
Grave Covell
Start Date
21-4-2012 10:00 AM
End Date
21-4-2012 12:00 PM
Charcterization of Cysteine Protease Inhibitor (CP8) Virulence Factor in Bovine and Feline Strains of T. Foetus
Grave Covell
Tritrichomonas foetus is related to the human parasite Trichomonas vaginalis. In T. vaginalis strains Cysteine proteases are thought to be major virulence factors. One such virulence factor is Cysteine Protease 8 (CP8). This study examines the role of CP8 in both bovine and feline clinical isolates. We have obtained samples from cows and cats that presented with clinical disease at the UC Davis Small Animal Hospital and are analyzing the expression of CP8 in all of these isolates. The characterization of this virulence factor will shed light on the pathogenesis of this important veterinary protozoal disease.