Impact of High Volume Energy Drink Consumption on Electrocardiographic and Blood Pressure Parameters: A Randomized Trial

Authors

Sachin A. Shah, University of the PacificFollow
Andy H. Szeto, University of the Pacific
Raechel Farewell, University of the Pacific
Allen Shek, University of the PacificFollow
Dorothy Fan, University of the Pacific
Kathy N. Quach, University of the Pacific
Mouchumi Bhattacharyya, University of the Pacific
Jasmine Elmiari, University of the Pacific
Winny Chan, University of the Pacific
Kate O'Dell, University of the Pacific
Nancy Nguyen, University of the Pacific
Tracey J. McGaughey, David Grant USAF Medical Center
Javed M. Nasir, David Grant USAF Medical Center
Sanjay Kaul, Cedars-Sinai Medical Center

Document Type

Article

Publication Title

Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease

ISSN

2047-9980

Volume

8

Issue

11

DOI

10.1161/JAHA.118.011318

First Page

011318

Publication Date

6-4-2019

Abstract

Background Energy drinks have been linked to an increase in emergency room visits and deaths. We aim to determine the impact of energy drinks on electrocardiographic and hemodynamic parameters in young healthy volunteers. Methods and Results A randomized, double-masked, placebo-controlled, crossover study was conducted in healthy volunteers. Participants consumed 32 oz of either energy drink A, energy drink B, or placebo within 60 minutes on 3 study days with a 6-day washout period in between. The primary end point of QT c interval and secondary end points of QT interval, PR interval, QRS duration, heart rate, and brachial and central blood pressures were measured at baseline, and every 30 minutes for 240 minutes. A repeated-measures 2-way analysis of variance was performed with the main effects of intervention, time, and an interaction of intervention and time. Thirty-four participants were included (age 22.1±3.0 years). The interaction term of intervention and time was statistically significant for Bazett's corrected QT interval, Fridericia's corrected QT interval, QT , PR , QRS duration, heart rate, systolic blood pressure, diastolic blood pressure, central systolic blood pressure, and central diastolic blood pressure (all P

Recommended Citation

Shah, S. A., Szeto, A. H., Farewell, R., Shek, A., Fan, D., Quach, K. N., Bhattacharyya, M., Elmiari, J., Chan, W., O'Dell, K., Nguyen, N., McGaughey, T. J., Nasir, J. M., & Kaul, S. (2019). Impact of High Volume Energy Drink Consumption on Electrocardiographic and Blood Pressure Parameters: A Randomized Trial. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 8(11), 011318. DOI: 10.1161/JAHA.118.011318
https://scholarlycommons.pacific.edu/phs-facarticles/386

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