Title

Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris

Authors

Geoff P. Lin-Cereghino, University of the PacificFollow
Joan Lin-Cereghino, University of the PacificFollow
Christine Ilgen, Keck Graduate Institute of Applied Life Sciences
James Cregg, Keck Graduate Institute of Applied Life SciencesFollow

Document Type

Article

Publication Title

Current Opinion in Biotechnology

Department

Biological Sciences

ISSN

0958-1669

Volume

13

Issue

4

DOI

10.1016/S0958-1669(02)00330-0

First Page

329

Last Page

332

Publication Date

8-1-2002

Abstract

The Pichia pastoris expression system offers economy, ease of manipulation, the ability to perform complex post-translational modifications, and high expression levels. Using this system, recent advances have been made in the quality of recombinant proteins in fermenter culture and in the quality of the protein product, namely improved secretion signals and glycosylation patterns.

Recommended Citation

Lin-Cereghino, G. P., Lin-Cereghino, J., Ilgen, C., & Cregg, J. (2002). Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris. Current Opinion in Biotechnology, 13(4), 329–332. DOI: 10.1016/S0958-1669(02)00330-0
https://scholarlycommons.pacific.edu/cop-facarticles/729