Exercise and Immune Function in Male and Female Chronic Fatigue Syndrome Patients

Authors

Christopher R. Snell, University of the PacificFollow
J. Mark Van Ness, University of the PacificFollow
David R. Strayer, Hemispherx PharmaFollow
Staci R. Stevens, Workwell FoundationFollow

ORCID

J. Mark Van Ness: https://orcid.org/0000-0001-5902-8735

Document Type

Article

Publication Title

International Journal of In Vivo Research

Department

Health, Exercise, and Sport Sciences Department

Volume

19

First Page

387

Last Page

390

Publication Date

1-1-2005

Abstract

Hyperactivition of an unwanted cellular cascade by the immune-related protein RNase L has been linked to reduced exercise capacity in persons with chronic fatigue syndrome (CFS). This investigation compares exercise capacities of CFS patients with deregulation of the RNase L pathway and CFS patients with normal regulation, while controlling for potentially confounding gender effects. Thirtyfive male and seventy-one female CFS patients performed graded exercise tests to voluntary exhaustion. Measures of peak VO2, peak heart rate, body mass index, perceived exertion, and respiratory quotient were entered into a two-way factorial analysis with gender and immune status as independent variables. A significant multivariate main effect was found for immune status (p

Recommended Citation

Snell, C. R., Van Ness, J. M., Strayer, D. R., & Stevens, S. R. (2005). Exercise and Immune Function in Male and Female Chronic Fatigue Syndrome Patients. International Journal of In Vivo Research, 19, 387–390.
https://scholarlycommons.pacific.edu/cop-facarticles/457