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Date of Award


Document Type


Degree Name

Master of Science (M.S.)


Graduate School

First Advisor

Donald Y Shirachi

Second Advisor

Judith K Jones

First Committee Member

Donald Y Shirachi

Second Committee Member

Judith K Jones

Third Committee Member

Marvin H. Malon

Fourth Committee Member

Paula A Wilson


tudies in teaching and non-teaching hospitals have shown that one- quarter to one-third of all patients receive an antimicrobial (AMC) drug during their hospital stay." 1-30 Many of these patients (ranging from 30 to 60%), particularly those on the surgical services, have no definite evidence of infection.

Inquiry regarding the use of AMC drugs can be traced back more than two decades. In 1961, the Commission on Professional and Hospital Activities in its Professional Activity Study (CPHA-PAS) surveyed 24 hospitals." They found that approximately 27% of all patients were given an AMC drug; however, it was estimated by PAS that only about 12% of these patients should have received AMC therapy under the most conservative medical practice.





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