Date of Award
1980
Document Type
Thesis
Degree Name
Master of Science (M.S.)
Department
Graduate School
First Advisor
Donald M. Pace
First Committee Member
Alice S. Hunter
Second Committee Member
Fuad M. Nahhas
Abstract
Although the differential response of malignant cells to hyperthermia was observed at the end of the last century, few investigations into the phenomenon were made until fairly recently. At first the results obtained were inconsistent due mostly to the inefficient techniques in use at the time. The advent of cell and tissue culture, increased knowledge in tumor biology, advances in molecular biology, and the development of equipment which could raise and monitor the temperature of tumors during hyperthermic treatments, have made the study of the effects of supranormal temperature on malignant neoplasias substantially more reliable.
The effectiveness of the combined treatment of hyperthermia and drugs has been established. A substantial amount of research to ascertain the most efficient uses of 2 combined treatments (or for finding or screening new drugs) remains to be done.
Pages
66
Recommended Citation
Duk, Fernando Alberto. (1980). In vitro comparative studies on the effect of vinblastine sulfate and hyperthermia on normal and transformed human lung fibroblasts. University of the Pacific, Thesis. https://scholarlycommons.pacific.edu/uop_etds/454
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