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Date of Award
1994
Document Type
Thesis - Pacific Access Restricted
Degree Name
Master of Science (M.S.)
Department
Pharmacy Practice
First Advisor
Robert B. Supernaw
First Committee Member
Michael A. Mergener
Second Committee Member
Linda L. Norton
Third Committee Member
Robert Oberlender
Fourth Committee Member
Michael Margoles
Abstract
A postmarketing surveillance survey of sumatriptan use comprised 32 questions including patient demographics, headache history, and sumatriptan experience. One hundred and forty-one questionnaires were sent out, and 109 patients responded; a total of 108 patients were included in the data analysis.
When compared with the national migraine population, on a percentage basis, significantly more African-Americans, females, young patients (less 45 years of age), and patients with higher mean incomes (>$45,000) were found in the present study of those taking sumatriptan (p
Males (N=8) and females (N=55) had a significantly different percentage of relief from the second dose of 94.7%±7.1 and 83.5%±24.4, respectively (p=0.01). An average percent of pain relief from the first dose in those weighing less or greater than 144 pounds was 76.5%±28.3 and 86.9%±16.4, respectively (p=0.023). The incidence of the adverse effects reported in this study was significantly greater than those reported in the literature (p<0.005).
Pages
89
Recommended Citation
Wang, Yu-Chin Lily. (1994). Postmarketing surveillance of sumatriptan : patient population, efficacy, and adverse effects. University of the Pacific, Thesis - Pacific Access Restricted. https://scholarlycommons.pacific.edu/uop_etds/2273
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