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Date of Award
Thesis - Pacific Access Restricted
Master of Science (M.S.)
First Committee Member
Marvin H. Malone
Second Committee Member
James W. Blankenship
Third Committee Member
In light of the limited and conflicting experimental data on food intake, body weight change and body energy metabolism following single-dose or long-term cocaine administration, the purpose of the present study was to further evaluate the dose-dependent acute and chronic (27 day) effects of two dose levels of cocaine on the following questions: i) Does chronic cocaine administration decrease food consumption and weight gain?; ii) To what extent does acute or chronic cocaine administration alter body carbohydrate stores (liver and skeletal muscle glycogen content)?; and iii). To what extent does acute or chronic cocaine administration affect plasma glucose and free fatty acid levels and thus hepatic glycogenolysis and adipose tissue lipolysis?
Xu, Yvette Yi-Wei. (1990). Effect of acute and chronic cocaine administration on food intake, body weight gain and energy substrate homeostasis in rats : a thesis .... University of the Pacific, Thesis - Pacific Access Restricted. https://scholarlycommons.pacific.edu/uop_etds/2203
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