Date of Award

1977

Document Type

Thesis

Degree Name

Master of Science (M.S.)

Department

Graduate Studies

First Advisor

Donald Y. Shirachi

First Committee Member

David S. Fries

Second Committee Member

Raymond M. Quock

Third Committee Member

Marvin Malone

Abstract

To many investigators, these observations suggested the existence of a molecular “pump” mechanism responsible for the maintenance of the ionic gradients. Extensive research over the last twenty years has resulted in the assignment of this role to the magnesium-dependent, sodium- and potassium-stimulated adenosine triphosphatase, first reported by Skou in 1957. This membrane-bound enzyme is the subject of the research presented in this thesis.

Pages

99

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