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Date of Award
Master of Science (M.S.)
F. R. Hunter
First Committee Member
W. Michael Kaill
Second Committee Member
The present kinetic study of the permeability of rabbit erythrocytes has established that carrier systems are involved in the penetration of certain non-electrolytes. Saturation, competitive inhibition, and butanol inhibition kinetics were used to demonstrate the presence of carrier systems and the values of half-saturation constants (ø) were determined for the following water soluble non-electrolytes: glycerol, ethylene glycol, urea, and thiourea.
These non-electrolytes are commonly used in permeability studies because they are relatively non-toxic and their small sizes allow penetration of the erythrocyte membrane within a reasonable length of time.
Chui, Arthur Hing-cheung. (1972). Facilitated diffusion in rabbit erythrocytes. University of the Pacific, Thesis. https://scholarlycommons.pacific.edu/uop_etds/1768
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