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Date of Award

1961

Document Type

Thesis

Degree Name

Master of Science (M.S.)

Department

Physiology and Pharmacology

First Advisor

Carl C. Riedesel

First Committee Member

Emerson G. Cobb

Second Committee Member

Hugh Wadman

Third Committee Member

Donald Alpert

Abstract

The studies and preliminary screening results reported in this paper developed from an initial interest in what appeared to be mildly toxic qualities of the bulbs of the common daffodil, Narcissus pseudonarcissus, Amaryllidaceae. The literature consulted does not shed much light on the mechanisms of the toxic agent or agents, and there appear to be some inconsistencies in respect to the alkaloids extracted. Part of this may be the result of differences in method of extraction, or perhaps lack of agreement on the identity of the actual plant bulbs used as a source of alkaloids. In regard to the chemical isolation of the alkaloids subsequently studied, the closest attention to the details described in several publications did not produce the results described.

Pages

44

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