Department
Nursing
Abstract
Background: Prostate cancer is one of the most common malignancies among men worldwide, with incidence rates rising steadily over the past decades. Although the widespread adoption of PSA screening has improved early detection, it has also sparked extensive debate regarding overdiagnosis and overtreatment. Against this backdrop, balancing the avoidance of unnecessary interventions with the need to ensure favorable patient outcomes has become a central challenge in clinical decision-making. Methods: Articles published from 2010 through 2025 were searched in five databases. The cross-sectional and cohort studies examined the effects of treatment options on localized prostate cancer. Results: From the analysis of the seven studies, the pooled effect on men’s sexual functions revealed logQR = 0.93, 95% CI [0.22, 1.64], p = 0.01, urinary functions at logQR = 2.38, 95% CI [1.29, 3.48], p < 0.01, bowel functions at logQR = 3.76, 95% CI [1.94, 5.59], p < 0.01. Age factors pooled at d = 0.76, 95% CI [0.11, 1.42], p = 0.02, PSA pooled at g = −0.61, 95% CI [−1.15, −0.07], p = 0.03, and clinical state pooled at logQR = 0.66, 95% CI [0.14, 1.17], p = 0.01. Conclusions: The quest for better management of prostate cancer among men continues to gain momentum in the face of opposition to radical surgery. Active surveillance has gained more popularity as it allows men to preserve those areas valued for quality of life. It has been observed that radical prostatectomy negatively affects the sexual, urinary, and bowel functions of men more than other treatment options.
Document Type
Article
Publication Date
8-2026
Publication Title
Open Journal of Nursing
Volume
16
Issue
8
DOI
doi.org/10.4236/ojn.2026.168033
First Page
454
Last Page
467
Recommended Citation
Omolewa, P. , Bressan, J. and Noureddine, N. (2026) The Effectiveness of Treatment Options for Localized Prostate Cancer: A Meta-Analysis of Cross-Sectional and Cohort Studies. Open Journal of Nursing, 16, 454-467. doi: 10.4236/ojn.2026.168033
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