Effect of Antibiotics on Compressive and Tensile Strength of Bone Cement
Poster Number
18A
Format
Poster Presentation
Faculty Mentor Name
Dr. Josh Steimel
Faculty Mentor Department
SOECS, Department of Mechanical Engineering
Abstract/Artist Statement
Antibiotic bone cement is an integral component of orthopedic surgery and is used in applications such as joint repair, treatment of bone fractures, and spinal surgery. Several biomechanical studies have been performed to determine various mechanical properties of antibiotic-impregnated bone cement. Here we investigate the compression and tensile strength of bone cement impregnated with various concentrations of vancomycin and tobramycin antibiotics. To assess the tensile and compression strength, cylindrical bone cement samples of the various concentrations were measured using a micrometer to record their height and diameter. Following modified ASTM standards, an Instron Universal Testing System with compressive flat grips was used to perform the tests. Both tests subjected the samples to a strain rate of 5mm/min. The compressive and tensile yield strength were measured and T-test comparisons illustrated that the concentration and mixture of antibiotics have a statistically significant effect on the mechanical properties of the yield strength of bone cement. Specifically, as the concentration of antibiotics increases generally there is a deterioration of yield strength.
Location
Information Commons, William Knox Holt Memorial Library and Learning Center
Start Date
29-4-2023 10:00 AM
End Date
29-4-2023 1:00 PM
Effect of Antibiotics on Compressive and Tensile Strength of Bone Cement
Information Commons, William Knox Holt Memorial Library and Learning Center
Antibiotic bone cement is an integral component of orthopedic surgery and is used in applications such as joint repair, treatment of bone fractures, and spinal surgery. Several biomechanical studies have been performed to determine various mechanical properties of antibiotic-impregnated bone cement. Here we investigate the compression and tensile strength of bone cement impregnated with various concentrations of vancomycin and tobramycin antibiotics. To assess the tensile and compression strength, cylindrical bone cement samples of the various concentrations were measured using a micrometer to record their height and diameter. Following modified ASTM standards, an Instron Universal Testing System with compressive flat grips was used to perform the tests. Both tests subjected the samples to a strain rate of 5mm/min. The compressive and tensile yield strength were measured and T-test comparisons illustrated that the concentration and mixture of antibiotics have a statistically significant effect on the mechanical properties of the yield strength of bone cement. Specifically, as the concentration of antibiotics increases generally there is a deterioration of yield strength.