Turning the Paddlewheel Towards Inorganic Synthesis
Format
Oral Presentation
Faculty Mentor Name
Qinliang Zhao
Faculty Mentor Department
Chemistry
Graduate Student Mentor Name
Michael Pastor
Graduate Student Mentor Department
Chemistry
Abstract/Artist Statement
Organic synthesis, widely used in pharmacies to produce common medicinal drugs, is quite relevant and of much significance to modern society. Organic chemistry deals largely with the reactivity of the functional groups: altering the functional groups on a molecule yields a new molecule. Synthesis of larger molecules for new drug design proves to be highly complex and more challenging to be achieved, however, an increasing amount of published coordination complexes have been proven to facilitate certain reactions serving as catalysts.
Generally, coordination complexes with one metal center are researched first because their convenient synthesis and control. Recently, bimetallic rhodium, iron and ruthenium complexes have demonstrated promising catalytic reactivities. However, their detailed mechanism and the role of each metal core are still not clear. To understand this, it is necessary to construct families of bimetallic complexes for systematic study.
For this research project, a family of bimetallic complexes of nickel supported by diarylformamidinate ligands have been synthesized and some have been examined by various instrumental techniques. Their synthesis involves a first step of ligand deprotonation with a strong base followed by transmetallation which replaces the main group metal with nickel. One compound that has been structurally characterized demonstrated a trigonal paddle-wheel structure. Full investigation of each compound is underway and progress will be detailed and presented.
Location
DeRosa University Center, Room 211
Start Date
28-4-2018 3:40 PM
End Date
28-4-2018 4:00 PM
Turning the Paddlewheel Towards Inorganic Synthesis
DeRosa University Center, Room 211
Organic synthesis, widely used in pharmacies to produce common medicinal drugs, is quite relevant and of much significance to modern society. Organic chemistry deals largely with the reactivity of the functional groups: altering the functional groups on a molecule yields a new molecule. Synthesis of larger molecules for new drug design proves to be highly complex and more challenging to be achieved, however, an increasing amount of published coordination complexes have been proven to facilitate certain reactions serving as catalysts.
Generally, coordination complexes with one metal center are researched first because their convenient synthesis and control. Recently, bimetallic rhodium, iron and ruthenium complexes have demonstrated promising catalytic reactivities. However, their detailed mechanism and the role of each metal core are still not clear. To understand this, it is necessary to construct families of bimetallic complexes for systematic study.
For this research project, a family of bimetallic complexes of nickel supported by diarylformamidinate ligands have been synthesized and some have been examined by various instrumental techniques. Their synthesis involves a first step of ligand deprotonation with a strong base followed by transmetallation which replaces the main group metal with nickel. One compound that has been structurally characterized demonstrated a trigonal paddle-wheel structure. Full investigation of each compound is underway and progress will be detailed and presented.