Title

Exploration of trans-2-(1,2,3-triazolyl)-cyclohexanols as potential inhibitors for fungal glycosidases

Poster Number

14C

Lead Author Major

Biochemistry

Lead Author Status

Senior

Second Author Major

Biochemistry

Second Author Status

Junior

Format

Poster Presentation

Faculty Mentor Name

Vyacheslav Samoshin

Faculty Mentor Email

vsamoshin@pacific.edu

Faculty Mentor Department

Chemistry

Additional Faculty Mentor Name

Nataliya Samoshina

Additional Faculty Mentor Email

nsamoshina@pacific.edu

Additional Faculty Mentor Department

Chemistry

Graduate Student Mentor Name

Mulinde R. Ruyonga

Graduate Student Mentor Email

r_ruyonga@u.pacific.edu

Graduate Student Mentor Department

Chemistry

Abstract/Artist Statement

A series of carbasugars based on trans-2-(1,2,3-triazolyl)-cyclohexanol moiety was synthesized for the first time by a “click reaction” of the corresponding azides and alkynes, and tested for the inhibitory activity towards fungal glycosidases from Aspergillus and Penicillium sp.

Location

DeRosa University Center, Ballroom

Start Date

29-4-2017 1:00 PM

End Date

29-4-2017 3:00 PM

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Apr 29th, 1:00 PM Apr 29th, 3:00 PM

Exploration of trans-2-(1,2,3-triazolyl)-cyclohexanols as potential inhibitors for fungal glycosidases

DeRosa University Center, Ballroom

A series of carbasugars based on trans-2-(1,2,3-triazolyl)-cyclohexanol moiety was synthesized for the first time by a “click reaction” of the corresponding azides and alkynes, and tested for the inhibitory activity towards fungal glycosidases from Aspergillus and Penicillium sp.