Variable diastereoselectivity in acylation of 2-substituted cyclohexanols

Poster Number

22

Lead Author Major

Biochemistry

Format

Poster Presentation

Faculty Mentor Name

V. Samoshin

Faculty Mentor Department

Chemistry

Abstract/Artist Statement

The ratio of diastereomeric products A and B in acylation of 2-substituted cyclohexanols was found to depend dramatically on the nature of substituents, solvent and additives. Unusual inversion of diastereoselectivity upon change of a solvent or addition of tertiary amines was found for certain combinations of reactants and conditions.

Location

DeRosa University Center, Ballroom

Start Date

21-4-2011 6:00 PM

End Date

21-4-2011 8:00 PM

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Apr 21st, 6:00 PM Apr 21st, 8:00 PM

Variable diastereoselectivity in acylation of 2-substituted cyclohexanols

DeRosa University Center, Ballroom

The ratio of diastereomeric products A and B in acylation of 2-substituted cyclohexanols was found to depend dramatically on the nature of substituents, solvent and additives. Unusual inversion of diastereoselectivity upon change of a solvent or addition of tertiary amines was found for certain combinations of reactants and conditions.