Total synthesis of new inhibitors for carbohydrate processing enzymes
Poster Number
14
Format
Poster Presentation
Abstract/Artist Statement
C-Glycosides are the chemically and metabolically stable analogs of carbohydrates. They can compete with natural carbohydrates in many biochemical processes. In particular, C-glycosides may interact with enzymes (the biocatalysts that transform carbohydrates) and deactivate (inhibit) them. Therefore, C-glycosides are potential therapeutic agents against many diseases. We synthesized new potential inhibitors for these enzymes, which formulas are shown below. The series of these compounds will be expanded and tested for the enzyme inhibitory activity.
Location
Pacific Geosciences Center
Start Date
24-4-2004 9:00 AM
End Date
24-4-2004 5:00 PM
Total synthesis of new inhibitors for carbohydrate processing enzymes
Pacific Geosciences Center
C-Glycosides are the chemically and metabolically stable analogs of carbohydrates. They can compete with natural carbohydrates in many biochemical processes. In particular, C-glycosides may interact with enzymes (the biocatalysts that transform carbohydrates) and deactivate (inhibit) them. Therefore, C-glycosides are potential therapeutic agents against many diseases. We synthesized new potential inhibitors for these enzymes, which formulas are shown below. The series of these compounds will be expanded and tested for the enzyme inhibitory activity.