"Comparison of prospective pharmacy monitoring vs. medical record disch" by G. A. Gibson, F. M. Butler et al.
 

Comparison of prospective pharmacy monitoring vs. medical record discharge coding for ADR surveillance

ORCiD

Eric Boyce: 0000-0002-5447-9016

Document Type

Poster

Conference Title/Conference Publication

American Society for Clinical Pharmacology & Therapeutics

Location

San Francisco, CA

Conference Dates

March 21-23, 1990

Date of Presentation

3-1-1990

Abstract

Hospitals monitor for ADRs by retrospective reviews (RR) of computerized discharge diagnosis, looking for ADR codes. This study evaluates this approach comparing it to a prospective (PR) ADR program. The PR program monitored ADRs via a clinical pharmacist on 5 medicine teams for 2 months. Suspected ADRs were investigated for severity & causality. PR ADRs were compared to ADRs from RR performed by Medical Records. 39 ADRs were identified by these approaches. Of these, 2 were detected by both approaches, 4 by RR, and 33 by PR. The sens., spec., PPV,NPV, of PR were 89,100,100, & 99%, respectively. The RR results were 15,99,29, & 97%. RR ADRs resulted in hospital admission rather than devloping in hospital. Serious and unexpected ADRs by PR & RR were 89,98,46, & 99%, and 17,98,14, & 99%, respectively. In conclusion, a retrospective discharge-based diagnosis system for collecting hospital ADRs is uacceptable as a sole surveillance system due to low sensitivity.

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