Anticoagulants: Newer ones, mechanisms, and perioperative updates

ORCiD

Adam M. Kaye: 0000-0002-7224-3322

Document Type

Article

Publication Title

Anesthesiology Clinics

ISSN

1932-2275

Volume

28

Issue

4

DOI

10.1016/j.anclin.2010.08.013

First Page

667

Last Page

679

Publication Date

12-1-2010

Abstract

With a growing number of new anticoagulant/antiplatelet agents being developed, it is likely that an increasing number of patients taking these drugs will present for surgery and other procedures. A familiarity with mechanisms of action and drug interactions helps to maintain optimal patient safety in the perioperative period. Furthermore, it is crucial for anesthesiologists to remain current on recommendations regarding discontinuation or need to continue the newer anticoagulants/antiplatelet drugs in patients presenting for surgery and/or regional anesthesia. Further studies are needed for monitoring of many of these newer agents and to identify antidotes. © 2010 Elsevier Inc.

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