The polyphenol ellagic acid exerts anti-inflammatory actions via disruption of store-operated calcium entry (SOCE) pathway activators and coupling mediators

Authors

Matthew T. Murphy, Western New England UniversityFollow
Xia Qin, First Affiliated Hospital of Chongqing Medical University
Shashank Kaul, Western New England University
Genaro Barrientos, Universidad de ChileFollow
Zhen Zou, Chongqing Medical UniversityFollow
Clinton B. Mathias, Western New England UniversityFollow
David Thomas, University of the PacificFollow
Diptiman D. Bose, Western New England UniversityFollow

Document Type

Article

Publication Title

European Journal of Pharmacology

ISSN

0014-2999

Volume

875

DOI

10.1016/j.ejphar.2020.173036

First Page

173036

Publication Date

5-15-2020

Abstract

Ellagic acid, a naturally occurring phenol found in a variety of fruits and nuts has been shown to possess anti-inflammatory properties. However, the mechanism of action behind its anti-inflammatory action is unclear. Using human Jurkat T cells, our study examined the effects of ellagic acid (EA) on Ca

Recommended Citation

Murphy, M. T., Qin, X., Kaul, S., Barrientos, G., Zou, Z., Mathias, C. B., Thomas, D., & Bose, D. D. (2020). The polyphenol ellagic acid exerts anti-inflammatory actions via disruption of store-operated calcium entry (SOCE) pathway activators and coupling mediators. European Journal of Pharmacology, 875, 173036. DOI: 10.1016/j.ejphar.2020.173036
https://scholarlycommons.pacific.edu/phs-facarticles/365