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Creation Date

2019

Description

The gene pitx1 is a switch for skeleton patterning (it is a transcription factor that controls a battery that patterns mesodermal tissues)9. Loss of a cis regulatory element that turns it on in pelvic regions leads to a reduced pelvis. This mutation is common in freshwater fish populations, where a smaller pelvis may be beneficial, but not in marine fish populations, where a more robust pelvis may be beneficial.

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Creative Commons Attribution-Noncommercial 4.0 License
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Keywords

evolution, development, evodevo, enhancer, GRN, gene regulatory network, pitx, stickleback

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