Presentation Category
Research
Introduction/Context/Diagnosis
Traditional antibiotics have been commonly used to treat several infectious diseases for decades, however, misuse and over-prescription have been escalating antibiotic resistance episodes. Boswellia serrata extract, derived from Boswellia trees prevalent in the Middle East, Africa, and Asia, offers multifaceted therapeutic benefits, including anti-cancer, anti-inflammatory, and anti-microbial effects. Periodontitis affects 20-50% of the global population, targeting the gingival tissues, supporting structures around teeth, and the alveolar bone. Porphyromonas gingivalis and Fusobacterium nucleatum are two prominent bacterial culprits in this pathogenesis. This study investigated the potential antimicrobial effects of B. serrata extracts against P. gingivalis and F. nucleatum. Using minimum inhibitory concentration and crystal violet staining methods, we evaluated its efficacy against P. gingivalis and F. nucleatum. Results demonstrate frankincense’s effectiveness in inhibiting P. gingivalis biofilm formation, and limited impact on F. nucleatum. These findings suggest a promising role for frankincense in managing periodontal infection. Further research into its mechanisms and potential synergies with existing treatments could lead to novel prevention and management strategies.
Location
Arthur A Dugoni School of Dentistry, 155 5th St, San Francisco, CA 94103, USA
Format
Presentation
Frankincense (Boswellia serrata) Extract Effects on Growth and Biofilm Formation of Porphyromonas gingivalis, and Its Intracellular Infection in Hujman Gingival Epithelial Cells
Arthur A Dugoni School of Dentistry, 155 5th St, San Francisco, CA 94103, USA
Traditional antibiotics have been commonly used to treat several infectious diseases for decades, however, misuse and over-prescription have been escalating antibiotic resistance episodes. Boswellia serrata extract, derived from Boswellia trees prevalent in the Middle East, Africa, and Asia, offers multifaceted therapeutic benefits, including anti-cancer, anti-inflammatory, and anti-microbial effects. Periodontitis affects 20-50% of the global population, targeting the gingival tissues, supporting structures around teeth, and the alveolar bone. Porphyromonas gingivalis and Fusobacterium nucleatum are two prominent bacterial culprits in this pathogenesis. This study investigated the potential antimicrobial effects of B. serrata extracts against P. gingivalis and F. nucleatum. Using minimum inhibitory concentration and crystal violet staining methods, we evaluated its efficacy against P. gingivalis and F. nucleatum. Results demonstrate frankincense’s effectiveness in inhibiting P. gingivalis biofilm formation, and limited impact on F. nucleatum. These findings suggest a promising role for frankincense in managing periodontal infection. Further research into its mechanisms and potential synergies with existing treatments could lead to novel prevention and management strategies.
Comments/Acknowledgements
Presentation Category: Research