Presentation Category
Research
Introduction/Context/Diagnosis
Abstract Objectives: This literature review aims to provide a comprehensive overview of recent research on dental pulp stem cells (DPSCs) in regenerative dentistry, addressing their characteristics, importance, isolation techniques, utilization in different dental specialties, and future prospects. Methods: Relevant studies published within the last 20 years were identified through database searches and manual selection. The review synthesizes findings from key research articles, including those investigating DPSC characterization, isolation methods, therapeutic applications, and future uses. Results: Dental pulp stem cells (DPSCs) are mesenchymal stem cells located within dental pulp tissue, exhibiting a high proliferation rate and multilineage differentiation capacity. DPSCs offer potential applications in tissue engineering and repair across various dental specialties, including endodontics, orthodontics, and periodontics. Isolation techniques such as mechanical dissociation, enzymatic digestion, and cell sorting enable the extraction and regeneration of DPSCs for research purposes. DPSC-based therapies hold promise for personalized dental treatment options, offering potential solutions for dental caries, periodontal disease, and craniofacial defects. Collaborative efforts between researchers, clinicians, and industry partners are essential to translate DPSC research findings into clinically viable treatments and improve patient outcomes in regenerative dentistry. Conclusions: Dental pulp stem cells represent a promising avenue for regenerative dentistry, offering potential applications in tissue repair and engineering across various dental specialties. Continued research efforts are warranted to unlock the full clinical potential of DPSCs and advance personalized approaches to dental treatment, ultimately improving patient care and outcomes in dental practice. Acknowledgements: Thank you to Dr. Tolarova and Dr. Tolar for their mentoring and help through this learning journey.
Location
Arthur A Dugoni School of Dentistry, 155 5th St, San Francisco, CA 94103, USA
Format
Presentation
Dental Pulp Stem Cells in Regenerative Dentistry
Arthur A Dugoni School of Dentistry, 155 5th St, San Francisco, CA 94103, USA
Abstract Objectives: This literature review aims to provide a comprehensive overview of recent research on dental pulp stem cells (DPSCs) in regenerative dentistry, addressing their characteristics, importance, isolation techniques, utilization in different dental specialties, and future prospects. Methods: Relevant studies published within the last 20 years were identified through database searches and manual selection. The review synthesizes findings from key research articles, including those investigating DPSC characterization, isolation methods, therapeutic applications, and future uses. Results: Dental pulp stem cells (DPSCs) are mesenchymal stem cells located within dental pulp tissue, exhibiting a high proliferation rate and multilineage differentiation capacity. DPSCs offer potential applications in tissue engineering and repair across various dental specialties, including endodontics, orthodontics, and periodontics. Isolation techniques such as mechanical dissociation, enzymatic digestion, and cell sorting enable the extraction and regeneration of DPSCs for research purposes. DPSC-based therapies hold promise for personalized dental treatment options, offering potential solutions for dental caries, periodontal disease, and craniofacial defects. Collaborative efforts between researchers, clinicians, and industry partners are essential to translate DPSC research findings into clinically viable treatments and improve patient outcomes in regenerative dentistry. Conclusions: Dental pulp stem cells represent a promising avenue for regenerative dentistry, offering potential applications in tissue repair and engineering across various dental specialties. Continued research efforts are warranted to unlock the full clinical potential of DPSCs and advance personalized approaches to dental treatment, ultimately improving patient care and outcomes in dental practice. Acknowledgements: Thank you to Dr. Tolarova and Dr. Tolar for their mentoring and help through this learning journey.
Comments/Acknowledgements
Presentation Category: Research