![Inflammasomes and danger signals in the immune system](https://scholarlycommons.pacific.edu/dugoni-facbooks/1007/thumbnail.jpg)
Title
Inflammasomes and danger signals in the immune system
ORCID
Dr. David Ojcius: 0000-0003-1461-4495
Files
Department
Biomedical Sciences
Document Type
Contribution to Book
Book Title
Reference Module in Biomedical Research
Editor(s)
Michael J. Caplan
Description
The innate immune system has evolved to recognize both pathogen- and damage-associated molecular patterns (PAMPs and DAMPs), which represent conserved microbial structures or generic markers of stress or damage, respectively, and to generate an appropriate response. One such response is the production of the critical cytokines interleukin-1β and interleukin-18, which follows incorporation of PAMP and DAMP signals, and requires the activation of protein complexes termed inflammasomes to generate mature cytokines.
Buy Link
http://doi.org/10.1016/B978-0-12-801238-3.00106-9
Find in WorldCat
https://www.worldcat.org/title/reference-module-in-biomedical-research/oclc/902812782&referer=brief_results
ISBN
978-0-12-801238-3
Publication Date
1-1-2014
Publisher
Elsevier
City
Amsterdam, Netherlands
Keywords
ATP; Caspase; DAMP; HMGB1; Immunology; Inflammasome; Inflammation; Interleukin-1β; NLRP3; Nod-like receptors; PAMP; Toll-like receptors
Disciplines
Dentistry
Recommended Citation
Lai, Hsin-Chih; Al-Kuhlani, Mufadhal; Ojcius, David M.; and Pettengill, Matthew A., "Inflammasomes and danger signals in the immune system" (2014). All Dugoni School of Dentistry Faculty Books and Book Chapters. 8.
https://scholarlycommons.pacific.edu/dugoni-facbooks/8
Comments
DOI: 10.1016/B978-0-12-801238-3.00106-9