The concanavalin a agglutinating system of cell membranes

ORCiD

Nejat Düzgüneş: 0000-0001-6159-1391

Department

Biomedical Sciences

Document Type

Article

Publication Title

BioSystems

ISSN

0303-2647

Volume

6

Issue

4

DOI

10.1016/0303-2647(75)90062-3

First Page

209

Last Page

216

Publication Date

1-1-1975

Abstract

The hopes raised by the finding of differential Concanavalin A (Con A) agglutinability of normal and transformed cells in efforts to quantify differences between these cell lines seem not to have been justified. In this paper, the development of information on the mechanism of action of Con A on the cell surface, as well as the theories put forward at each stage of this development are surveyed. In this respect, investigations on Con A constitute a case history in biological research. The involvement of glycoproteins and galactosyltransferases in cell-cell interactions and their relations to Con A are also reviewed. © 1975.

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