Consomic rats parental strains differ in sensory perception, pain developed following nerve injury and in IL-1 beta and IL-6 levels

Authors

Andrew L. Young, University of the PacificFollow
Mythili Kalladka, Eastman Institute for Oral Health
Archana Viswanath, Tufts University School of Dental Medicine
Tal Zusman, Rutgers University
Junad Khan, Eastman Institute for Oral Health

Department

Orthodontics

Document Type

Article

Publication Title

Pathophysiology : the official journal of the International Society for Pathophysiology

ISSN

0928-4680

Volume

25

Issue

2

DOI

10.1016/j.pathophys.2018.03.001

First Page

137

Last Page

141

Publication Date

6-1-2018

Abstract

Highlights
* Differences in response to sensory stimuli, pain development and cytokine secretion of parental inbred rat strains used to construct consomic lines may have a genetic basis.
* Following chronic constriction injury, Dahl Salt Sensitive rats developed significant hypersensitivity, which correlated with the IL-6 and IL-1β secretion.

Recommended Citation

Young, A. L., Kalladka, M., Viswanath, A., Zusman, T., & Khan, J. (2018). Consomic rats parental strains differ in sensory perception, pain developed following nerve injury and in IL-1 beta and IL-6 levels. Pathophysiology : the official journal of the International Society for Pathophysiology, 25(2), 137–141. DOI: 10.1016/j.pathophys.2018.03.001
https://scholarlycommons.pacific.edu/dugoni-facarticles/502