Bite force and pattern measurements for dental pain assessment in the rat
Department
Orthodontics
Document Type
Article
Publication Title
Neuroscience Letters
ISSN
0304-3940
Volume
447
Issue
2--3
DOI
10.1016/j.neulet.2008.10.008
First Page
175
Last Page
178
Publication Date
12-1-2008
Abstract
We present simple method to assess dental pain in the awake rat. Using a sensitive strain gauge we examined changes in bite strength and bite pattern in rats following dental injury. Rats with dental injury displayed a significant reduction in mean peak bite strength and an altered bite cluster pattern. Both changes in the dental injury rats were reversed by an analgesic dose of morphine, and this could be reversed with naloxone. These changes were not observed in naive control animals. This simple method significantly improves our ability to evaluate dental pain syndromes.
Recommended Citation
Khan, J.,
Benoliel, R.,
Herzberg, U.,
Mannes, A. J.,
Caudle, R. M.,
Young, A. L.,
&
Eliav, E.
(2008).
Bite force and pattern measurements for dental pain assessment in the rat.
Neuroscience Letters, 447(2--3), 175–178.
DOI: 10.1016/j.neulet.2008.10.008
https://scholarlycommons.pacific.edu/dugoni-facarticles/5