Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface
David M. Ojcius: 0000-0003-1461-4495
Reproductive Biology and Endocrinology
The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover recent aspects of immune privilege and the innate immune system at the feto-maternal interface, citing examples of the role played by microbial infections in fetal demise.
Caucheteux, S. M.,
Ojcius, D. M.
Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface.
Reproductive Biology and Endocrinology, 1, 121–127.
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