Variable diastereoselectivity in acylation of 2-substituted cyclohexanols

Authors

Andrey V. Samoshin, University of the Pacific
Jasper Visser
Matthew Curtis, University of the PacificFollow
Andreas H. Franz, University of the PacificFollow

Document Type

Conference Presentation

Department

Chemistry

Conference Title

241st American Chemical Society (ACS) National Meeting & Exposition

Organization

American Chemical Society (ACS)

Location

Anaheim, CA

Conference Dates

March 27-31, 2011

Date of Presentation

3-30-2011

Abstract

The ratio of diastereomeric products A and B in acylation of 2-substituted cyclohexanols was found to depend dramatically on the nature of substituents, solvent and additives. Unusual inversion of diastereoselectivity upon change of a solvent or addition of tertiary amines was found for certain combinations of reactants and conditions.

Comments

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Recommended Citation

Samoshin, A. V., Visser, J., Curtis, M., & Franz, A. H. (2011). Variable diastereoselectivity in acylation of 2-substituted cyclohexanols. Paper presented at 241st American Chemical Society (ACS) National Meeting & Exposition in Anaheim, CA.
https://scholarlycommons.pacific.edu/cop-facpres/340