Ventilatory Functioning During Serial Cardiopulmonary Exercise Testing in People With and Without Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Document Type

Conference Presentation

Department

Health, Exercise, and Sport Sciences Department

Conference Title

Virtual Scientific Conference

Organization

International Association of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Location

Virtual

Date of Presentation

8-20-2021

Abstract

Todd Davenport (DPT) from Stockton, CA, USA looked at quantifying ventilatory functioning at rest and during activity in those with and without ME/CFS. Subjects received 2 maximal CPETs on a braked bicycle ergometer, administered 24 hours apart. Throughout each test, measurements of breath-by-breath gas samples, workload, heart rate, breathing rate, tidal volume, end tidal oxygen, and end tidal carbon dioxide were taken at rest, ventilatory anaerobic threshold (VAT), and peak exertion. The subjects were matched and included 37 females with ME/CFS and 38 healthy sedentary women. There was a significantly blunted rise in VO2 max (volume of oxygen consumed) in ME/CFS which was functionally disabling. The ME/CFS patients experienced overall lowered performance. The heart rate showed a blunted rise in ME/CFS patients associated with exercise, and the respiratory rate increased markedly in the second test. Minute ventilation and tidal volume were lower in the ME/CFS group at VAT and peak exertion. He concluded that those with ME/CFS demonstrate abnormal pulmonary measurements on CPET that may correlate with abnormal metabolic and cardiac functioning. Potential effects on pulmonary function of short-term PEM induced by CPET remain unclear.

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