Campus Access Only

All rights reserved. This publication is intended for use solely by faculty, students, and staff of University of the Pacific. No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, now known or later developed, including but not limited to photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the author or the publisher.

Date of Award


Document Type


Degree Name

Master of Science (M.S.)


Graduate School

First Advisor

James C. King

First Committee Member

Francis W. Sayre

Second Committee Member

Herschel G. Frye


For centuries, researchers have attempted to devise the ideal parenteral nutritional product readily amenable to physiological requirements. Hyperalimentation, intravenous alimentation, parenteral alimentation, parenteral feeding, and total parenteral nutrition are synonyms which refer to a method of complete intravenous nutrition reserved for patients demonstrating negative nitrogen balance.

The nutrient solution appeared to accommodate levels of potassium phosphate, calcium gluconate, and magnesium sulfate well in excess of “usual” therapeutic concentrations. Similarly, commonly employed vitamin supplements and insulin were examined in combination with the hyperalimentation solution and failed to demonstrate signs of physical incompatibility. However, instrumental analysis, i.e., U.V. spectroscopy and thin-layer chromatography, suggested, in fact, there may have been chemical interaction of Solu B Forte and MVI once admixed with the amino acids/dextrose solution. Yet, results of thin-layer chromatography did not appear to substantiate chemical interaction between MVI and the amino acids solution. The investigator contends further study of multiple vitamin infusion stability be completed before definite conclusions are formulated regarding their compatibility in this nutritional infusate.





Rights Statement

Rights Statement

No Known Copyright. URI:
The organization that has made the Item available reasonably believes that the Item is not restricted by copyright or related rights, but a conclusive determination could not be made. Please refer to the organization that has made the Item available for more information. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use.