Date of Award
1963
Document Type
Thesis
Degree Name
Master of Science (M.S.)
Department
Chemistry
First Advisor
Emerson G. Cobb
First Committee Member
W. H. Wadman
Second Committee Member
Milton E. Fuller
Abstract
It is the purpose of this work to prepare a series of these chalcones containing the thiophene ring.
The compounds were prepared by the condensation of a series of benzaldehydes with acetylthiophene dissolved in dry ethylacetate and saturated with dry HCl. The benzaldehyde compounds were benzaldehyde, m-hydroxybenzaldehyde, o-hydroxybenzaldehyde, O-p-dihydroxybenzaldehyde and vanillin. To prevent the oxidation of the hydroxy groups of the benzaldehydes, the compounds were benzolated with benzoylchloride. The condensed products were debenzoylated with NaOH solution in an atmosphere of nitrogen to prevent oxidation during the debenzoylation process.
Pages
50
Recommended Citation
Newey, John M.. (1963). Hydroxy derivatives of benzalthiophenone. University of the Pacific, Thesis. https://scholarlycommons.pacific.edu/uop_etds/384
