Campus Access Only

All rights reserved. This publication is intended for use solely by faculty, students, and staff of University of the Pacific. No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, now known or later developed, including but not limited to photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the author or the publisher.

Date of Award

1960

Document Type

Thesis

Degree Name

Master of Science (M.S.)

Department

Chemistry

First Advisor

Emerson G. Cobb

First Committee Member

W. Hugh Wadman

Second Committee Member

Herschel G. Frye

Abstract

The objective of this study is the preparation of a tetracycline-boron-10 derivative which is stable under biological conditions. The boron-10 should then provide a concentration of material capable of accepting thermal neutrons, thus producing localized high-energy alpha radiation. The fact that the tetracyclines are not retained by normal tissue should remove the danger of destruction of this tissue.

Pages

22

Included in

Chemistry Commons

Share

COinS