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Date of Award


Document Type


Degree Name

Master of Science (M.S.)



First Advisor

Herschel G Frye

First Committee Member

Howard K Zimmerman

Second Committee Member

Emerson Cobb


The chenistry of diamino dicarboxylic acids together with that of monoamino dicarboxylie and monocarboxylic acids in of great importance to the chemist because of the rolation- ship of these compounds to the biochemistry of cancer.

Diamino dicarboxylic acids in general, contain two asymmetric carbon atoms and may exist in one optically inactive and two optically active forma. Alpha-omoga diamino pinolic acid is the only member of the alpha-omoga diamino dicarboxylic acids thus far known to occur naturally.





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