Effects of Rutaecarpine on the Pharmacokinetics of Caffeine in Rats
Poster Number
17
Introduction/Abstract
Rutaecarpine, a pentacyclic indolopyridoquinazolinone alkaloid isolated from the unripe fruit of Evodia rutaecarpa, has been reported as a potent inducer of CYP1A2 enzyme in rats. There are natural herbal supplements containing rutaecarpine that are designed to speed up the removal of caffeine (CYP1A2 substrate) from blood.
Location
DUC Ballroom A&B
Format
Poster Presentation
Poster Session
Afternoon
Effects of Rutaecarpine on the Pharmacokinetics of Caffeine in Rats
DUC Ballroom A&B
Rutaecarpine, a pentacyclic indolopyridoquinazolinone alkaloid isolated from the unripe fruit of Evodia rutaecarpa, has been reported as a potent inducer of CYP1A2 enzyme in rats. There are natural herbal supplements containing rutaecarpine that are designed to speed up the removal of caffeine (CYP1A2 substrate) from blood.