Nonsteroidal antiinflammatory drugs: Review of factors guiding formulary considerations
The selection and use of nonsteroidal anti-inflammatory drugs (NSAIDs) is complicated by the introduction of new products and formulations and the emergence of additional information on older products. Numerous NSAIDs are now available by prescription and/or over the counter and are indicated for use in a variety of inflammatory, pain, and other disorders (table 1).
In general, all NSAIDs are equivalent in efficacy for their approved indications,[1-14] but they may differ in acquisition cost, dosage form, dosing interval, and the occurrence and severity of adverse effects, overdose, and drug interactions. Approved indications, studies of off-label uses, and data on protection against specific diseases or NSAID-induced adverse effects in select populations provide further information for formulary decision-making. This article provides an overview and analysis of available clinical data to aid in the optimal selection of systemic NSAIDs for general or specific patient populations.
Boyce, E. G.,
Nonsteroidal antiinflammatory drugs: Review of factors guiding formulary considerations.
Formulary, 35(2), 142–168.