In an early gastrula, mesoderm (red) involution occurs at the dorsal lip of the blastopore. Most mesoderm will involute here. Over time, involution spreads around the blastopore lip as the lip gets smaller and smaller due to epiboly by the ectoderm (blue).
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gastrulation, xenopus, frog, fate map, epiboly, ectoderm, endoderm, mesoderm, evodevo, dorsal lip of the blastopore, blastopore