Journal of the California Dental Association
The glial cell line-derived neurotrophic factor (GDNF) family has a role in neuron growth within the peripheral and central nervous systems. This makes it a potential therapeutic agent for neurological conditions like Parkinson’s disease and epilepsy. GDNF has also been implicated in murine odontogenesis. In permanent and deciduous human dental pulp stem cells, this study found that GDNF family members and receptors are expressed, indicating neurotrophic factors may play a role in dental pulp regeneration.
Comparison of expression of the GDNF family neurotrophic factors in dental pulp stem cells with deciduous and adult teeth.
Journal of the California Dental Association, 12(45), 667–669.