Title

Neurotrophic Factors and Their Potential Applications in Tissue Regeneration

Document Type

Article

Publication Title

Archivum immunologiae et therapiae experimentalis

ISSN

1661-4917

Volume

64

Issue

2

DOI

10.1007/s00005-015-0376-4

First Page

89

Last Page

99

Publication Date

4-1-2016

Abstract

Neurotrophic factors are growth factors that can nourish neurons and promote neuron survival and regeneration. They have been studied as potential drug candidates for treating neurodegenerative diseases. Since their identification, there are more and more evidences to indicate that neurotrophic factors are also expressed in non-neuronal tissues and regulate the survival, anti-inflammation, proliferation and differentiation in these tissues. This mini review summarizes the characteristics of the neurotrophic factors and their potential clinical applications in the regeneration of neuronal and non-neuronal tissues.

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