ORCID

0000-0001-5951-9630

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Document Type

Contribution to Book

Department

Biological Sciences

Book Title

Significance, Prevention and Control of Food Related Diseases

Editor(s)

Hussaini Anthony ed Makun

Description

Biomonitoring of food and environmental matrices is critical for the rapid and sensitive diagnosis, treatment, and prevention of diseases caused by toxins. The U.S. Centers for Disease Control and Prevention (CDC) has noted that toxins from bacteria, fungi, algae, and plants present an ongoing public health threat, especially since some of these toxins could compromise security of the food supply. Botulinum neurotoxins (BoNTs), produced by Clostridium spp., are among those bacterial toxins that pose life-threatening danger to humans. BoNTs inhibit the release of acetylcholine at peripheral cholinergic nerve terminals and cause flaccid paralysis. BoNTs are grouped in seven serotypes and many subtypes within these groups. Rapid and accurate identification of these toxins in contaminated food as well as in environmental matrices can help direct treatment. Herein, we discuss current methods to detect BoNTs with a focus on how these technologies have been used to identify toxins in various food and environmental matrices. We also discuss the emergence of new serotypes and subtypes of BoNTs and the increasing number of cases of botulism in wildlife. Finally, we consider how environmental changes impact food safety for humans and present new challenges for detection technology.

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https://www.worldcat.org/title/significance-prevention-and-control-of-food-related-diseases/oclc/1021308915

ISBN

978-9-53512-277-7

Publication Date

1-1-2016

Publisher

InTech Publishers

City

Rijeka, Croatia

First Page

125

Last Page

144

Keywords

botulism, toxins, food matrix, environmental detection, foodborne illness

Disciplines

Biology

Comments

Recommended Citation:

Luisa W. Cheng, Kirkwood M. Land, Christina Tam, David L. Brandon and Larry H. Stanker (April 13th 2016). Technologies for Detecting Botulinum Neurotoxins in Biological and Environmental Matrices, Significance, Prevention and Control of Food Related Diseases, Hussaini Anthony Makun, IntechOpen, DOI: 10.5772/63064. Available from: https://www.intechopen.com/books/significance-prevention-and-control-of-food-related-diseases/technologies-for-detecting-botulinum-neurotoxins-in-biological-and-environmental-matrices

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Creative Commons Attribution 3.0 License
This work is licensed under a Creative Commons Attribution 3.0 License.

https://www.intechopen.com/books/significance-prevention-and-control-of-food-related-diseases/technologies-for-detecting-botulinum-neurotoxins-in-biological-and-environmental-matrices

Technologies for Detecting Botulinum Neurotoxins in Biological and Environmental Matrices
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